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The map label for this gene is yafC [H]

Identifier: 78066418

GI number: 78066418

Start: 1971380

End: 1972306

Strand: Direct

Name: yafC [H]

Synonym: Bcep18194_A4949

Alternate gene names: 78066418

Gene position: 1971380-1972306 (Clockwise)

Preceding gene: 78066410

Following gene: 78066419

Centisome position: 53.37

GC content: 60.41

Gene sequence:

>927_bases
GTGGACAAGCTACTCGCCTTGCGGGCATTCATTGACGTCGCAGAAACGGGGGGCTTTTCAAAGGCGGCTCGCCGCATGGG
GGTTGCCACTTCGTCGGTGACTCGCCTGATGGACGCGTTGGAGCAGTCGCTTGGAAGCGCGTTACTGACTCGGACGACAC
GTCAGGTGACGTTGACGGATGCCGGTGCTGCGTATCTGGAGCAGATCACACGCGTGCTGTCGGACCTCGACGAAGCCGAT
GGCAGTGTGTCCGACACGGGCATTGACGCAGTTGGACCGCTGCGTGTTTCCATGCCGGTGACTTTCGGGCGCCTGTGCCT
GGGGCCGCACATAGCAAGCTTCCTGCAGCAGCATCCCCGCGTGTCCCTGGACCTGGTGCTGTCGGATTCGACTCTCGATC
TGGCTGCCGAGCGAATTGACGTTGCGGTCCGCATCGGCTCACCTGCAAACCAGCCCAATCTGATCGTCAATCGCCTGGCG
GAGCATCATCGCTATGTGGTCGCGAGCCATGACTATCTGCAGAGCAACGGGGTGCCCGCCTCACCGGAAGATCTGCGACA
CCATCAATGCCTGCGTTTTGCGTACGAAGCTGCTTTGCAGCGGTGGTCGTTCACTCGCACAGACGGCACCGTACATGTCG
AGATCAATGGCAGGCTTTCGGTGAACAACTCGGACGTGCTGCGCGAGGCGGTTATCAGCGGGTTTGGTATTGCGCTGCTG
CCCCAATGGCTCGTCGAAGAGGATGTGGTGGCGGGGCGGCTGAGGCGGCTTTTCGAAGACTACTCGGTCAACCCGCTCGA
CCAGACCGTCTGCGTTTATGCCGCCTATCTTCCGAATCGCCGCCACTCACGCAAAGTGCATGCGTTGCTGGATTTTCTTC
GACATCGCATCACGAACTCCGGTGCGTTCTCGGATGCTTCGAGCTAG

Upstream 100 bases:

>100_bases
GCGTTGACGGTACGAGTACTTTAGGCTTTGCGTCAGAGTAAGTGAATATGAGTCAATCGCAAACCAGCGTTGCGGTGTGT
GCAAAGGGAAAGGACATAAC

Downstream 100 bases:

>100_bases
GTAGCGATACTGCGCGCCGGCGTGAGCGGATCGCTGGGAAATGGATCCGCGCATGGCTGTGATCGGCCGCGCACCAAGAC
TTGCTCTACGACGCACTCAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDKLLALRAFIDVAETGGFSKAARRMGVATSSVTRLMDALEQSLGSALLTRTTRQVTLTDAGAAYLEQITRVLSDLDEAD
GSVSDTGIDAVGPLRVSMPVTFGRLCLGPHIASFLQQHPRVSLDLVLSDSTLDLAAERIDVAVRIGSPANQPNLIVNRLA
EHHRYVVASHDYLQSNGVPASPEDLRHHQCLRFAYEAALQRWSFTRTDGTVHVEINGRLSVNNSDVLREAVISGFGIALL
PQWLVEEDVVAGRLRRLFEDYSVNPLDQTVCVYAAYLPNRRHSRKVHALLDFLRHRITNSGAFSDASS

Sequences:

>Translated_308_residues
MDKLLALRAFIDVAETGGFSKAARRMGVATSSVTRLMDALEQSLGSALLTRTTRQVTLTDAGAAYLEQITRVLSDLDEAD
GSVSDTGIDAVGPLRVSMPVTFGRLCLGPHIASFLQQHPRVSLDLVLSDSTLDLAAERIDVAVRIGSPANQPNLIVNRLA
EHHRYVVASHDYLQSNGVPASPEDLRHHQCLRFAYEAALQRWSFTRTDGTVHVEINGRLSVNNSDVLREAVISGFGIALL
PQWLVEEDVVAGRLRRLFEDYSVNPLDQTVCVYAAYLPNRRHSRKVHALLDFLRHRITNSGAFSDASS
>Mature_308_residues
MDKLLALRAFIDVAETGGFSKAARRMGVATSSVTRLMDALEQSLGSALLTRTTRQVTLTDAGAAYLEQITRVLSDLDEAD
GSVSDTGIDAVGPLRVSMPVTFGRLCLGPHIASFLQQHPRVSLDLVLSDSTLDLAAERIDVAVRIGSPANQPNLIVNRLA
EHHRYVVASHDYLQSNGVPASPEDLRHHQCLRFAYEAALQRWSFTRTDGTVHVEINGRLSVNNSDVLREAVISGFGIALL
PQWLVEEDVVAGRLRRLFEDYSVNPLDQTVCVYAAYLPNRRHSRKVHALLDFLRHRITNSGAFSDASS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=33.4437086092715, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=33.7837837837838, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1787589, Length=298, Percent_Identity=30.2013422818792, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=31.0344827586207, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789639, Length=304, Percent_Identity=27.3026315789474, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=26.4808362369338, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=26.2068965517241, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789173, Length=262, Percent_Identity=30.1526717557252, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI157672245, Length=168, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786448, Length=248, Percent_Identity=25.4032258064516, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=21.7821782178218, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790011, Length=305, Percent_Identity=20.983606557377, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786713, Length=71, Percent_Identity=50.7042253521127, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33839; Mature: 33839

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLALRAFIDVAETGGFSKAARRMGVATSSVTRLMDALEQSLGSALLTRTTRQVTLTD
CCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
AGAAYLEQITRVLSDLDEADGSVSDTGIDAVGPLRVSMPVTFGRLCLGPHIASFLQQHPR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCC
VSLDLVLSDSTLDLAAERIDVAVRIGSPANQPNLIVNRLAEHHRYVVASHDYLQSNGVPA
CEEEEEEECCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCEEEEECHHHHCCCCCC
SPEDLRHHQCLRFAYEAALQRWSFTRTDGTVHVEINGRLSVNNSDVLREAVISGFGIALL
CHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCEEECCCHHHHHHHHHHCCCHHHH
PQWLVEEDVVAGRLRRLFEDYSVNPLDQTVCVYAAYLPNRRHSRKVHALLDFLRHRITNS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GAFSDASS
CCCCCCCC
>Mature Secondary Structure
MDKLLALRAFIDVAETGGFSKAARRMGVATSSVTRLMDALEQSLGSALLTRTTRQVTLTD
CCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
AGAAYLEQITRVLSDLDEADGSVSDTGIDAVGPLRVSMPVTFGRLCLGPHIASFLQQHPR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCC
VSLDLVLSDSTLDLAAERIDVAVRIGSPANQPNLIVNRLAEHHRYVVASHDYLQSNGVPA
CEEEEEEECCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCEEEEECHHHHCCCCCC
SPEDLRHHQCLRFAYEAALQRWSFTRTDGTVHVEINGRLSVNNSDVLREAVISGFGIALL
CHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCEEECCCHHHHHHHHHHCCCHHHH
PQWLVEEDVVAGRLRRLFEDYSVNPLDQTVCVYAAYLPNRRHSRKVHALLDFLRHRITNS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GAFSDASS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]