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The map label for this gene is yafC [H]

Identifier: 78066378

GI number: 78066378

Start: 1926744

End: 1927643

Strand: Direct

Name: yafC [H]

Synonym: Bcep18194_A4908

Alternate gene names: 78066378

Gene position: 1926744-1927643 (Clockwise)

Preceding gene: 78066374

Following gene: 78066379

Centisome position: 52.16

GC content: 64.44

Gene sequence:

>900_bases
ATGGACAGCTTCGCGCTGAACGTTTTTGTACAGGCTGCGGATACGCGCAGTTTCGTTGCGGCCGGCCGTGTGCTCGGCAT
CTCCGCTTCGGGTATCGGCAAGAGCGTGACGCGGCTCGAACAGAGCCTCGGGGTACGACTGTTTCATCGCAGCACGCGCA
GCGTCGCGTTGACGACGGAAGGCGCGCTATTTCTCGAACGCGCGCGGCGGATCCTCGCCGAATTCGATGCGGCGCAGGCT
GAGCTTTCGGAGGCGAGCTCGGTGCCGAGAGGGCGGTTGCGGATCGGTTTGCCGATGGTGGGCGATCCGTTTTTGCCGGT
GTTTTCGGCGTTTCGACAGCGCTATCCGGAGATCGAGCTCGATCTCGATTTCGACAACCGCATGGCGGACATCATCGAGG
AGGGCTATGACGCGGTCGTGCGCAGCGGCGACGTCGACGATTCCCGCCTGACGGCGCGGCCGCTGGGGCGCTTCCGGATG
ATGCTGGTGGGGGCACCCGACTATTTCGCGCGGCGGGGCACGCCTTCGCACCCGCGCGAGCTCGTCGAACACGACTGCAT
CCAGTTCCGGATGCCGAACACGGGGAAGCTGCAAACGTGGCAACTGCGGTGCGACGCGGGCGACGAGCCGGAGCTGCGGC
TGCCGACCGCGATTACCTGCAATACCAACGAGGCGCGCATGTACTTCGCGATCACGGGCGTCGGCATTGCGTACGCGTCG
GAATTTTCCGCGAAGCAGGCGCTCGAGGCGGGGCAACTGGTGACGGTGCTCGATGACTACACGGCCGAACAGAATACGTT
CCAGTTGCTCTGGCCGTCAGGCCGTCACGTGACGCCGCGGCTGCGCGCCTTCATCGATTTTGTCTCCGAGCACGTGCAGC
TCGACAAGACTCGTTCCTGA

Upstream 100 bases:

>100_bases
GGGATGACAGCGAAGTTATCGCCTTTCCCAACAGGAATTAAGTACGGTAGAGTTCCCGGCTGAACGGACAATCTGTCCGC
TATTCAAGGAGCGTCGCTTC

Downstream 100 bases:

>100_bases
CGAGGACGGGGTGCGTAAGTCTAGACTGGATCTCTCTGTCAGAGTCAGATCAGTTAGTGATTGCTTGGACGCCACTTCGT
CTATGGTCGTGATCGACGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDSFALNVFVQAADTRSFVAAGRVLGISASGIGKSVTRLEQSLGVRLFHRSTRSVALTTEGALFLERARRILAEFDAAQA
ELSEASSVPRGRLRIGLPMVGDPFLPVFSAFRQRYPEIELDLDFDNRMADIIEEGYDAVVRSGDVDDSRLTARPLGRFRM
MLVGAPDYFARRGTPSHPRELVEHDCIQFRMPNTGKLQTWQLRCDAGDEPELRLPTAITCNTNEARMYFAITGVGIAYAS
EFSAKQALEAGQLVTVLDDYTAEQNTFQLLWPSGRHVTPRLRAFIDFVSEHVQLDKTRS

Sequences:

>Translated_299_residues
MDSFALNVFVQAADTRSFVAAGRVLGISASGIGKSVTRLEQSLGVRLFHRSTRSVALTTEGALFLERARRILAEFDAAQA
ELSEASSVPRGRLRIGLPMVGDPFLPVFSAFRQRYPEIELDLDFDNRMADIIEEGYDAVVRSGDVDDSRLTARPLGRFRM
MLVGAPDYFARRGTPSHPRELVEHDCIQFRMPNTGKLQTWQLRCDAGDEPELRLPTAITCNTNEARMYFAITGVGIAYAS
EFSAKQALEAGQLVTVLDDYTAEQNTFQLLWPSGRHVTPRLRAFIDFVSEHVQLDKTRS
>Mature_299_residues
MDSFALNVFVQAADTRSFVAAGRVLGISASGIGKSVTRLEQSLGVRLFHRSTRSVALTTEGALFLERARRILAEFDAAQA
ELSEASSVPRGRLRIGLPMVGDPFLPVFSAFRQRYPEIELDLDFDNRMADIIEEGYDAVVRSGDVDDSRLTARPLGRFRM
MLVGAPDYFARRGTPSHPRELVEHDCIQFRMPNTGKLQTWQLRCDAGDEPELRLPTAITCNTNEARMYFAITGVGIAYAS
EFSAKQALEAGQLVTVLDDYTAEQNTFQLLWPSGRHVTPRLRAFIDFVSEHVQLDKTRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=35.0515463917526, Blast_Score=180, Evalue=8e-47,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=33.9041095890411, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1787589, Length=284, Percent_Identity=32.7464788732394, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=28.4246575342466, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=29.6296296296296, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=26.6211604095563, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=26.643598615917, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=25.5892255892256, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789173, Length=286, Percent_Identity=24.1258741258741, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693105, Length=194, Percent_Identity=27.319587628866, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788706, Length=301, Percent_Identity=24.5847176079734, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI157672245, Length=173, Percent_Identity=31.2138728323699, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=29.3706293706294, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=139, Percent_Identity=33.8129496402878, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082132, Length=284, Percent_Identity=24.6478873239437, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33364; Mature: 33364

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSFALNVFVQAADTRSFVAAGRVLGISASGIGKSVTRLEQSLGVRLFHRSTRSVALTTE
CCCEEEEEEEEECCCHHHHHHCEEEEEECCCCCHHHHHHHHHHCEEEEECCCCEEEEEEC
GALFLERARRILAEFDAAQAELSEASSVPRGRLRIGLPMVGDPFLPVFSAFRQRYPEIEL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEE
DLDFDNRMADIIEEGYDAVVRSGDVDDSRLTARPLGRFRMMLVGAPDYFARRGTPSHPRE
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCHHH
LVEHDCIQFRMPNTGKLQTWQLRCDAGDEPELRLPTAITCNTNEARMYFAITGVGIAYAS
HHHHHHEEEECCCCCCEEEEEEEECCCCCCCEECCEEEEECCCCCEEEEEEEECHHHHHH
EFSAKQALEAGQLVTVLDDYTAEQNTFQLLWPSGRHVTPRLRAFIDFVSEHVQLDKTRS
HHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDSFALNVFVQAADTRSFVAAGRVLGISASGIGKSVTRLEQSLGVRLFHRSTRSVALTTE
CCCEEEEEEEEECCCHHHHHHCEEEEEECCCCCHHHHHHHHHHCEEEEECCCCEEEEEEC
GALFLERARRILAEFDAAQAELSEASSVPRGRLRIGLPMVGDPFLPVFSAFRQRYPEIEL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEE
DLDFDNRMADIIEEGYDAVVRSGDVDDSRLTARPLGRFRMMLVGAPDYFARRGTPSHPRE
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCHHH
LVEHDCIQFRMPNTGKLQTWQLRCDAGDEPELRLPTAITCNTNEARMYFAITGVGIAYAS
HHHHHHEEEECCCCCCEEEEEEEECCCCCCCEECCEEEEECCCCCEEEEEEEECHHHHHH
EFSAKQALEAGQLVTVLDDYTAEQNTFQLLWPSGRHVTPRLRAFIDFVSEHVQLDKTRS
HHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]