BacMap

Definition	Burkholderia sp. 383 chromosome 1, complete genome.
Accession	NC_007510
Length	3,694,126

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The map label for this gene is fabG [H]

Identifier: 78066355

GI number: 78066355

Start: 1900611

End: 1901318

Strand: Reverse

Name: fabG [H]

Synonym: Bcep18194_A4885

Alternate gene names: 78066355

Gene position: 1901318-1900611 (Counterclockwise)

Preceding gene: 78066357

Following gene: 78066353

Centisome position: 51.47

GC content: 65.25

Gene sequence:

>708_bases
ATGAGCGCATCCAAAGTCATCATCGTCACCGGCGCATCGCAAGGCATCGGCGCGGCAACCGTCGACGCATTCCGGGCCCG
CGGCCATCGCGTCGTCGCCACGTCACGTTCGATCGGGCCGTCGAACGATCCCGATCTCGTCACCGTCGCGGGCGACATCG
GCGACGCGGCCGTCGCACGGCGCGTGGTCGACGCCGCCATCGAACGCTTCGGCCGCGTCGACACGCTCGTCAACAACGCG
GGTGTGTTCATCGCGAAGCCGTTCACGCAGTACACCGCGGACGACTATGCGCAGATCACGAGCGTCAACCTGAATGGCTT
CTTCCACGTCACGCAACATGCGATCGCCGCGATGCAGAAGCACGGTAGCGGCCACGTGGTCAGCATCACGACGAGCCTGA
TCGATCACGCGAACAGCAACGTGCCGTCGGTGCTCGCGTCGTTGACGAAAGGCGGATTGAATGCGGCGACGAAGTCGCTC
GCGATCGAGTATGCGAAGGCCGGCATTCGCGTGAATGCCGTGTCGCCCGGGATCATCAAGTCGCCGATGCATGCGCCCGA
AACGCACGCGACGCTCGCATCGCTGCATCCGGTCGGCCGCATGGGCGAGATGAGCGACATCGTCGACGCGATCCTGTACC
TGGACTCGGCGCCGTTCGTCACGGGCGAGATCCTGCATGTCGACGGCGGCCAGAGCGCCGGGCATTGA

Upstream 100 bases:

>100_bases
GGTGTTCGAGATCGTGACCGGCGCGCCTACAGTTCGCCCATCGGATTCACGGATCCGGTCGGCACTGAAGCCGAAAACCC
TTCACCTATCGAGGCAAATC

Downstream 100 bases:

>100_bases
GTCGCGGCGTCGAAACCGCGCGCCGGCGCGTCTAGCGCGATGCGCCGGCCCGTTTGGTGCGTGTGCCGGTCGCGGGCCTG
GCTGGCGCGCGTGCCAGATG

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSASKVIIVTGASQGIGAATVDAFRARGHRVVATSRSIGPSNDPDLVTVAGDIGDAAVARRVVDAAIERFGRVDTLVNNA
GVFIAKPFTQYTADDYAQITSVNLNGFFHVTQHAIAAMQKHGSGHVVSITTSLIDHANSNVPSVLASLTKGGLNAATKSL
AIEYAKAGIRVNAVSPGIIKSPMHAPETHATLASLHPVGRMGEMSDIVDAILYLDSAPFVTGEILHVDGGQSAGH

Sequences:

>Translated_235_residues
MSASKVIIVTGASQGIGAATVDAFRARGHRVVATSRSIGPSNDPDLVTVAGDIGDAAVARRVVDAAIERFGRVDTLVNNA
GVFIAKPFTQYTADDYAQITSVNLNGFFHVTQHAIAAMQKHGSGHVVSITTSLIDHANSNVPSVLASLTKGGLNAATKSL
AIEYAKAGIRVNAVSPGIIKSPMHAPETHATLASLHPVGRMGEMSDIVDAILYLDSAPFVTGEILHVDGGQSAGH
>Mature_234_residues
SASKVIIVTGASQGIGAATVDAFRARGHRVVATSRSIGPSNDPDLVTVAGDIGDAAVARRVVDAAIERFGRVDTLVNNAG
VFIAKPFTQYTADDYAQITSVNLNGFFHVTQHAIAAMQKHGSGHVVSITTSLIDHANSNVPSVLASLTKGGLNAATKSLA
IEYAKAGIRVNAVSPGIIKSPMHAPETHATLASLHPVGRMGEMSDIVDAILYLDSAPFVTGEILHVDGGQSAGH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=34.8547717842324, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=27.6679841897233, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=28.6919831223629, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=28.4, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=30.4, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=27.6, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4504505, Length=187, Percent_Identity=33.1550802139037, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4503301, Length=230, Percent_Identity=29.1304347826087, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.7959183673469, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=31.6872427983539, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=30.1204819277108, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788459, Length=190, Percent_Identity=32.6315789473684, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.4552845528455, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=29.3877551020408, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=29.9595141700405, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=27.8008298755187, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.9352226720648, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787820, Length=233, Percent_Identity=21.4592274678112, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=27.5193798449612, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=30.5019305019305, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=28.2945736434109, Blast_Score=113, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=31.5352697095436, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.9433962264151, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=30.9236947791165, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=26.2548262548263, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=27.5471698113208, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=26.5151515151515, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=30.2788844621514, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=28.4615384615385, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.4820717131474, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=27.6923076923077, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=25.2873563218391, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=29.277566539924, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.8973384030418, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=26.4591439688716, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=26, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=28.7449392712551, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=29.7619047619048, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.0676691729323, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=199, Percent_Identity=34.6733668341709, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=24.2537313432836, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=25.5725190839695, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=24.7104247104247, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=28.3400809716599, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=29.2553191489362, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=225, Percent_Identity=25.3333333333333, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=31.3725490196078, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.8725099601594, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.5555555555556, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=33.0612244897959, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=28.9795918367347, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=32.0987654320988, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24644337, Length=230, Percent_Identity=26.5217391304348, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007236, Length=232, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=31.7460317460317, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=26.2745098039216, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24663911, Length=237, Percent_Identity=28.2700421940928, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641232, Length=234, Percent_Identity=26.0683760683761, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24269; Mature: 24138

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASKVIIVTGASQGIGAATVDAFRARGHRVVATSRSIGPSNDPDLVTVAGDIGDAAVAR
CCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHH
RVVDAAIERFGRVDTLVNNAGVFIAKPFTQYTADDYAQITSVNLNGFFHVTQHAIAAMQK
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCEEEEEECCCEEHHHHHHHHHHHH
HGSGHVVSITTSLIDHANSNVPSVLASLTKGGLNAATKSLAIEYAKAGIRVNAVSPGIIK
CCCCCEEEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCHHC
SPMHAPETHATLASLHPVGRMGEMSDIVDAILYLDSAPFVTGEILHVDGGQSAGH
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
SASKVIIVTGASQGIGAATVDAFRARGHRVVATSRSIGPSNDPDLVTVAGDIGDAAVAR
CCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHH
RVVDAAIERFGRVDTLVNNAGVFIAKPFTQYTADDYAQITSVNLNGFFHVTQHAIAAMQK
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCEEEEEECCCEEHHHHHHHHHHHH
HGSGHVVSITTSLIDHANSNVPSVLASLTKGGLNAATKSLAIEYAKAGIRVNAVSPGIIK
CCCCCEEEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCHHC
SPMHAPETHATLASLHPVGRMGEMSDIVDAILYLDSAPFVTGEILHVDGGQSAGH
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]