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The map label for this gene is qseB [H]

Identifier: 78066346

GI number: 78066346

Start: 1894573

End: 1895238

Strand: Reverse

Name: qseB [H]

Synonym: Bcep18194_A4876

Alternate gene names: 78066346

Gene position: 1895238-1894573 (Counterclockwise)

Preceding gene: 78066349

Following gene: 78066345

Centisome position: 51.3

GC content: 66.67

Gene sequence:

>666_bases
ATGCATATCCTGCTGGTAGAAGACGATGTCATGCTGGCCGACGCCGTTTGCGCGGGCCTCAGGCAGAACGGCTGGCGCGC
GGACTGGTCGGCCGACGTGCCGGCCGCGCGGCTCGCGCTCGTCGGCCACGGCTACGACGCGGTGCTGCTCGACCTGCAAC
TGCCGGGTGCGTCCGGTTTCACGCTGCTCGCCGCGATGCGTGCGAACTACGACCCGACGCCGGTATTGATCGTGACCGCA
CGCGATCAGTTGAGCGACCGGATCCGCGGCCTCGACGCAGGCGCCGACGACTATCTCGTGAAGCCGTTCCAGCTCGACGA
ACTCTACGCACGGTTGCGCGCGCTGACGCGCCGCAGCCAGGGCCGCGTGTCGGAACGCCTGATCTACCGCGACGTGCACG
TCGATCCGGCTCGCAAGGAAGTCACGCGTGCCGGCGAACCCGTTGCGCTCAGCATTCACGAGTACCGCACGCTGCTCGCG
TTGATGGAGCGGCAAGGCCGCGTCGTCACGCGCACGCAGCTCGAAGAGCGCGTGTACGGCAACGACAGCGCAATCGAAAG
CAACACGATCGCGGTGTACATCCATCAACTTCGGCGCAAGCTCGGCGACGAACTGATCGTGACGGTGCATGGCTTCGGCT
ATCGCGTCGGGGAGAGCCCGGCATGA

Upstream 100 bases:

>100_bases
GCAATGCGGCGAATGGCCCGCATCGTGGCCCCCGGGCTTTAAGAAGTTTTTAATCGCGGTCGGTCAGATTGGCGACCTCG
ACATTCGAGGAGCGAAACCG

Downstream 100 bases:

>100_bases
AGTCGCTACGCGTGCGCCTGCTCGCGACCGTGATGGCGGCGGTCGTCGTGTTCTGGGCGAGCTGGGGGGCGTTTCTCGGT
ATCGGCCTGTGGCGTGAACA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MHILLVEDDVMLADAVCAGLRQNGWRADWSADVPAARLALVGHGYDAVLLDLQLPGASGFTLLAAMRANYDPTPVLIVTA
RDQLSDRIRGLDAGADDYLVKPFQLDELYARLRALTRRSQGRVSERLIYRDVHVDPARKEVTRAGEPVALSIHEYRTLLA
LMERQGRVVTRTQLEERVYGNDSAIESNTIAVYIHQLRRKLGDELIVTVHGFGYRVGESPA

Sequences:

>Translated_221_residues
MHILLVEDDVMLADAVCAGLRQNGWRADWSADVPAARLALVGHGYDAVLLDLQLPGASGFTLLAAMRANYDPTPVLIVTA
RDQLSDRIRGLDAGADDYLVKPFQLDELYARLRALTRRSQGRVSERLIYRDVHVDPARKEVTRAGEPVALSIHEYRTLLA
LMERQGRVVTRTQLEERVYGNDSAIESNTIAVYIHQLRRKLGDELIVTVHGFGYRVGESPA
>Mature_221_residues
MHILLVEDDVMLADAVCAGLRQNGWRADWSADVPAARLALVGHGYDAVLLDLQLPGASGFTLLAAMRANYDPTPVLIVTA
RDQLSDRIRGLDAGADDYLVKPFQLDELYARLRALTRRSQGRVSERLIYRDVHVDPARKEVTRAGEPVALSIHEYRTLLA
LMERQGRVVTRTQLEERVYGNDSAIESNTIAVYIHQLRRKLGDELIVTVHGFGYRVGESPA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=46.1187214611872, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1790552, Length=214, Percent_Identity=42.5233644859813, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=36.3636363636364, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=35.3211009174312, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=34.4036697247706, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=33.6363636363636, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=34.841628959276, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=31.1111111111111, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=31.5555555555556, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=31.6017316017316, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.4841628959276, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.2576419213974, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=33.4801762114537, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=26.9565217391304, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24630; Mature: 24630

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILLVEDDVMLADAVCAGLRQNGWRADWSADVPAARLALVGHGYDAVLLDLQLPGASGF
CEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCCCEEEEEEECCCCCCH
TLLAAMRANYDPTPVLIVTARDQLSDRIRGLDAGADDYLVKPFQLDELYARLRALTRRSQ
HHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
GRVSERLIYRDVHVDPARKEVTRAGEPVALSIHEYRTLLALMERQGRVVTRTQLEERVYG
CCHHHHHEEEECCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCEEEHHHHHHHHCC
NDSAIESNTIAVYIHQLRRKLGDELIVTVHGFGYRVGESPA
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCC
>Mature Secondary Structure
MHILLVEDDVMLADAVCAGLRQNGWRADWSADVPAARLALVGHGYDAVLLDLQLPGASGF
CEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCCCEEEEEEECCCCCCH
TLLAAMRANYDPTPVLIVTARDQLSDRIRGLDAGADDYLVKPFQLDELYARLRALTRRSQ
HHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
GRVSERLIYRDVHVDPARKEVTRAGEPVALSIHEYRTLLALMERQGRVVTRTQLEERVYG
CCHHHHHEEEECCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCEEEHHHHHHHHCC
NDSAIESNTIAVYIHQLRRKLGDELIVTVHGFGYRVGESPA
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]