Click here to switch to the map view.

The map label for this gene is qseC [H]

Identifier: 78066345

GI number: 78066345

Start: 1893191

End: 1894576

Strand: Reverse

Name: qseC [H]

Synonym: Bcep18194_A4875

Alternate gene names: 78066345

Gene position: 1894576-1893191 (Counterclockwise)

Preceding gene: 78066346

Following gene: 78066344

Centisome position: 51.29

GC content: 68.9

Gene sequence:

>1386_bases
ATGAAGTCGCTACGCGTGCGCCTGCTCGCGACCGTGATGGCGGCGGTCGTCGTGTTCTGGGCGAGCTGGGGGGCGTTTCT
CGGTATCGGCCTGTGGCGTGAACAGCGCGGCTGGCGCGACGGCATGCTTGAAAGTGCCGCGCAACTGCTGCTCTTGTCGC
TGCCCGATGCGATCGATCGCCTGCCCGCCGCGAACGCCCAGGCGGTGGTGTCGAACACCGCGTATGGCAAATACGACGTC
GCGTTCCAGGTCTGGGTCGATGGCCGCAACGTGATGCACAGCGCGGATGCGCCGGGGCCGGCACTCAAGGCCGACCTGCA
GGACGGATACGGGGTGAGCACCGGGCGCGGCGTCGCGCACGACGAGACCTGGCGGGTGTACTCGCTGTCGGATCCGGCGG
GCCGGATTCACGTTCAGACGGGCGGGCCGGCCACGACCTGGCAGGAGAAGGCGAACAATGCGCTGCAACTCGGCCTGTTC
AATACGGCGGTGATGCTCGGGATGCTGGGCGTCGTGATCTGGTGGGTGATCCGCTGGTCGTTCGGGCCGGTGCGCGACGT
CCAGCATGCGATCCAGCGCAAGGCCGCGTTCGATTTCTCGCCGTTGCCGCTGGTGACGCTGCCGCGCGAACTCCGCCCGC
TCGTCGAATCGTTCAATCGCTTGCTCGCACGGTTGAGTCAGGCCGTCGACACCGAGCGTCGTTTCATCGGCGATGCGGCG
CACGAGTTGCGCACGCCGCTCGCGGCGTTGTCGGCCCAGGCGGAAGTGGCATTGCAGGCGGACAGTCTGGCGGACAAGAA
CGACGCATTGCGTCGGCTGGCAACGGGCGTCGAGCGCAGCGCGCGGCTATCCGGGCAATTGCTCGAACTGGCGCGGCTGG
ATGCCGGATCGCGTGCCGACCAGCATGGGCCGGTCGACCTGTCGCGGCTCGTTGCACTGATCGCGAGCGACTTCGACGCG
GCCGCCCATGCGCGCCGGCAGACGATGCGGATCGCGGTCGAACCGGTGCGCGTCTGGGGTGACCTGGACGAGATTGCGAT
CGCGGTGCGCAACCTGATCGACAACGCGCTGCGTTACGGCCGTGACGGCGGGCGGGTCGAGATCACGTGCGACAGCCCTG
CCGATGCGGACGGCGGGCGGGTCAGGCTGCGGATCGCGGACGACGGGCCCGGTGTGCCGCTCGGCGAGCGCGAGCGGATC
TTCGAACGCTTTTACCGGGTGCCGGGGACGGTACAGCCGGGCAGCGGCATCGGCCTGTCGCTCGTTGCACGGATCGCCGA
GTCGCACGGCGGGTCGGTCGAGGTGGCGGCCGGTATCGAGGGAAACGGGCTGGCGGTGATCCTGTCGTTCCCGATCTGGG
TGGATCCGGCGCGCTGGCAGCGTTAG

Upstream 100 bases:

>100_bases
ACACGATCGCGGTGTACATCCATCAACTTCGGCGCAAGCTCGGCGACGAACTGATCGTGACGGTGCATGGCTTCGGCTAT
CGCGTCGGGGAGAGCCCGGC

Downstream 100 bases:

>100_bases
TGTGCTGCGCCGCGCCCTGCCCGACCGATCCCGGTCTATGCTGTGCGATCGAAACCGTCAATCGAGGAGCAGCCGATGTC
CGATGCAACGACCGGAAACG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MKSLRVRLLATVMAAVVVFWASWGAFLGIGLWREQRGWRDGMLESAAQLLLLSLPDAIDRLPAANAQAVVSNTAYGKYDV
AFQVWVDGRNVMHSADAPGPALKADLQDGYGVSTGRGVAHDETWRVYSLSDPAGRIHVQTGGPATTWQEKANNALQLGLF
NTAVMLGMLGVVIWWVIRWSFGPVRDVQHAIQRKAAFDFSPLPLVTLPRELRPLVESFNRLLARLSQAVDTERRFIGDAA
HELRTPLAALSAQAEVALQADSLADKNDALRRLATGVERSARLSGQLLELARLDAGSRADQHGPVDLSRLVALIASDFDA
AAHARRQTMRIAVEPVRVWGDLDEIAIAVRNLIDNALRYGRDGGRVEITCDSPADADGGRVRLRIADDGPGVPLGERERI
FERFYRVPGTVQPGSGIGLSLVARIAESHGGSVEVAAGIEGNGLAVILSFPIWVDPARWQR

Sequences:

>Translated_461_residues
MKSLRVRLLATVMAAVVVFWASWGAFLGIGLWREQRGWRDGMLESAAQLLLLSLPDAIDRLPAANAQAVVSNTAYGKYDV
AFQVWVDGRNVMHSADAPGPALKADLQDGYGVSTGRGVAHDETWRVYSLSDPAGRIHVQTGGPATTWQEKANNALQLGLF
NTAVMLGMLGVVIWWVIRWSFGPVRDVQHAIQRKAAFDFSPLPLVTLPRELRPLVESFNRLLARLSQAVDTERRFIGDAA
HELRTPLAALSAQAEVALQADSLADKNDALRRLATGVERSARLSGQLLELARLDAGSRADQHGPVDLSRLVALIASDFDA
AAHARRQTMRIAVEPVRVWGDLDEIAIAVRNLIDNALRYGRDGGRVEITCDSPADADGGRVRLRIADDGPGVPLGERERI
FERFYRVPGTVQPGSGIGLSLVARIAESHGGSVEVAAGIEGNGLAVILSFPIWVDPARWQR
>Mature_461_residues
MKSLRVRLLATVMAAVVVFWASWGAFLGIGLWREQRGWRDGMLESAAQLLLLSLPDAIDRLPAANAQAVVSNTAYGKYDV
AFQVWVDGRNVMHSADAPGPALKADLQDGYGVSTGRGVAHDETWRVYSLSDPAGRIHVQTGGPATTWQEKANNALQLGLF
NTAVMLGMLGVVIWWVIRWSFGPVRDVQHAIQRKAAFDFSPLPLVTLPRELRPLVESFNRLLARLSQAVDTERRFIGDAA
HELRTPLAALSAQAEVALQADSLADKNDALRRLATGVERSARLSGQLLELARLDAGSRADQHGPVDLSRLVALIASDFDA
AAHARRQTMRIAVEPVRVWGDLDEIAIAVRNLIDNALRYGRDGGRVEITCDSPADADGGRVRLRIADDGPGVPLGERERI
FERFYRVPGTVQPGSGIGLSLVARIAESHGGSVEVAAGIEGNGLAVILSFPIWVDPARWQR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=454, Percent_Identity=32.5991189427313, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786783, Length=350, Percent_Identity=29.1428571428571, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=31.5789473684211, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788279, Length=234, Percent_Identity=31.6239316239316, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790551, Length=285, Percent_Identity=28.4210526315789, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787374, Length=281, Percent_Identity=27.7580071174377, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=303, Percent_Identity=27.0627062706271, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=27.0758122743682, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=303, Percent_Identity=25.4125412541254, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=29.4605809128631, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=25.2100840336134, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=24.2553191489362, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786912, Length=277, Percent_Identity=29.2418772563177, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=268, Percent_Identity=26.1194029850746, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=22.9249011857708, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=22.1719457013575, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=27.0642201834862, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=22.9838709677419, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50080; Mature: 50080

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLRVRLLATVMAAVVVFWASWGAFLGIGLWREQRGWRDGMLESAAQLLLLSLPDAIDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
LPAANAQAVVSNTAYGKYDVAFQVWVDGRNVMHSADAPGPALKADLQDGYGVSTGRGVAH
CCCCCCHHEEECCCCCCEEEEEEEEECCCHHEECCCCCCCCHHHCCCCCCCCCCCCCCCC
DETWRVYSLSDPAGRIHVQTGGPATTWQEKANNALQLGLFNTAVMLGMLGVVIWWVIRWS
CCCEEEEEECCCCCEEEEECCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
FGPVRDVQHAIQRKAAFDFSPLPLVTLPRELRPLVESFNRLLARLSQAVDTERRFIGDAA
CCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPLAALSAQAEVALQADSLADKNDALRRLATGVERSARLSGQLLELARLDAGSRAD
HHHHHHHHHHHCHHHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QHGPVDLSRLVALIASDFDAAAHARRQTMRIAVEPVRVWGDLDEIAIAVRNLIDNALRYG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHHHHHHHHC
RDGGRVEITCDSPADADGGRVRLRIADDGPGVPLGERERIFERFYRVPGTVQPGSGIGLS
CCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHH
LVARIAESHGGSVEVAAGIEGNGLAVILSFPIWVDPARWQR
HHHHHHHCCCCCEEEEECCCCCCEEEEEECCEEECHHHCCC
>Mature Secondary Structure
MKSLRVRLLATVMAAVVVFWASWGAFLGIGLWREQRGWRDGMLESAAQLLLLSLPDAIDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
LPAANAQAVVSNTAYGKYDVAFQVWVDGRNVMHSADAPGPALKADLQDGYGVSTGRGVAH
CCCCCCHHEEECCCCCCEEEEEEEEECCCHHEECCCCCCCCHHHCCCCCCCCCCCCCCCC
DETWRVYSLSDPAGRIHVQTGGPATTWQEKANNALQLGLFNTAVMLGMLGVVIWWVIRWS
CCCEEEEEECCCCCEEEEECCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
FGPVRDVQHAIQRKAAFDFSPLPLVTLPRELRPLVESFNRLLARLSQAVDTERRFIGDAA
CCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPLAALSAQAEVALQADSLADKNDALRRLATGVERSARLSGQLLELARLDAGSRAD
HHHHHHHHHHHCHHHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QHGPVDLSRLVALIASDFDAAAHARRQTMRIAVEPVRVWGDLDEIAIAVRNLIDNALRYG
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHHHHHHHHC
RDGGRVEITCDSPADADGGRVRLRIADDGPGVPLGERERIFERFYRVPGTVQPGSGIGLS
CCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHH
LVARIAESHGGSVEVAAGIEGNGLAVILSFPIWVDPARWQR
HHHHHHHCCCCCEEEEECCCCCCEEEEEECCEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]