Click here to switch to the map view.

The map label for this gene is cobO [H]

Identifier: 78066270

GI number: 78066270

Start: 1814370

End: 1814972

Strand: Reverse

Name: cobO [H]

Synonym: Bcep18194_A4800

Alternate gene names: 78066270

Gene position: 1814972-1814370 (Counterclockwise)

Preceding gene: 78066271

Following gene: 78066269

Centisome position: 49.13

GC content: 65.51

Gene sequence:

>603_bases
ATGAAAACCGACGCCGAATCCCATCAACGGATGACCGAACGCCGCCGTGCGGGCCACGAGAAGAAGCAGGCCGCCGCCGT
CAACGAAAAGGGCCTGCTGATCGTCAATACCGGCAACGGCAAGGGCAAGAGCACGGCCGCGTTCGGCATGGCCGTGCGCG
TACTCGGCCACGGCATGCGGCTCGGCGTCGTGCAGTTCATCAAGGGCGCGCTGCACACGTCCGAGCGCGACTTCCTCGGC
GCGGTGGCCGAATGCGATTTCGTGACGATGGGCGACGGCTATACGTGGAACACGCAGAACCGCGACGCCGACATCGCGAC
CGCGCGCAAGGGCTGGGACGAGGCGCGCCGGATGATCGAGAGCGGCGACTACCGGATGGTGATCCTCGACGAGCTGAACA
CGGTGCTGAAGTACGAATACCTGCCGCTCGACGAAGTGCTCGCGACGCTCACCGCACGTCCGGACTCGGTGCACGTCGTC
GTGACCGGGCGGCATGCGCCCGATGCGCTGATCGATGCGGCCGACCTCGTCACCGAAATGCGGCTTGTCAAGCATCCGTA
CAAGGAACAAGGCGTGAAGGCGCAGCGCGGCGTGGAGTTCTGA

Upstream 100 bases:

>100_bases
GCCTGCTCGGCCCCAAATCCATCCGGGACGGCGTGACGGTCGCACTCGCCGGCCCGCTCTGAACCCTTTTGTTTCGCTTT
CTTTCGACAGGACGAATCCG

Downstream 100 bases:

>100_bases
GCATGCTCGCCTGCCCCGCGCTGTTCGTCAGTGCGCCCGCGTCGGGCCAGGGCAAGACGTCGGTGACGGCGGGCCTCGCG
CGGCTGCACCGCCGGCTCGG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKTDAESHQRMTERRRAGHEKKQAAAVNEKGLLIVNTGNGKGKSTAAFGMAVRVLGHGMRLGVVQFIKGALHTSERDFLG
AVAECDFVTMGDGYTWNTQNRDADIATARKGWDEARRMIESGDYRMVILDELNTVLKYEYLPLDEVLATLTARPDSVHVV
VTGRHAPDALIDAADLVTEMRLVKHPYKEQGVKAQRGVEF

Sequences:

>Translated_200_residues
MKTDAESHQRMTERRRAGHEKKQAAAVNEKGLLIVNTGNGKGKSTAAFGMAVRVLGHGMRLGVVQFIKGALHTSERDFLG
AVAECDFVTMGDGYTWNTQNRDADIATARKGWDEARRMIESGDYRMVILDELNTVLKYEYLPLDEVLATLTARPDSVHVV
VTGRHAPDALIDAADLVTEMRLVKHPYKEQGVKAQRGVEF
>Mature_200_residues
MKTDAESHQRMTERRRAGHEKKQAAAVNEKGLLIVNTGNGKGKSTAAFGMAVRVLGHGMRLGVVQFIKGALHTSERDFLG
AVAECDFVTMGDGYTWNTQNRDADIATARKGWDEARRMIESGDYRMVILDELNTVLKYEYLPLDEVLATLTARPDSVHVV
VTGRHAPDALIDAADLVTEMRLVKHPYKEQGVKAQRGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=195, Percent_Identity=44.6153846153846, Blast_Score=174, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22168; Mature: 22168

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDAESHQRMTERRRAGHEKKQAAAVNEKGLLIVNTGNGKGKSTAAFGMAVRVLGHGMR
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHH
LGVVQFIKGALHTSERDFLGAVAECDFVTMGDGYTWNTQNRDADIATARKGWDEARRMIE
HHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCEEECCCCCCCCHHHHHCCHHHHHHHHH
SGDYRMVILDELNTVLKYEYLPLDEVLATLTARPDSVHVVVTGRHAPDALIDAADLVTEM
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHH
RLVKHPYKEQGVKAQRGVEF
HHHHCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MKTDAESHQRMTERRRAGHEKKQAAAVNEKGLLIVNTGNGKGKSTAAFGMAVRVLGHGMR
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHH
LGVVQFIKGALHTSERDFLGAVAECDFVTMGDGYTWNTQNRDADIATARKGWDEARRMIE
HHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCEEECCCCCCCCHHHHHCCHHHHHHHHH
SGDYRMVILDELNTVLKYEYLPLDEVLATLTARPDSVHVVVTGRHAPDALIDAADLVTEM
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHH
RLVKHPYKEQGVKAQRGVEF
HHHHCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]