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The map label for this gene is tcp [H]

Identifier: 78066220

GI number: 78066220

Start: 1741896

End: 1743734

Strand: Direct

Name: tcp [H]

Synonym: Bcep18194_A4750

Alternate gene names: 78066220

Gene position: 1741896-1743734 (Clockwise)

Preceding gene: 78066219

Following gene: 78066221

Centisome position: 47.15

GC content: 67.92

Gene sequence:

>1839_bases
ATGCACCGGGTGAAGCAATGCTTCGAAGCGACGGGCCTGTCCCGTCCATCACGACGCAACACAGGAAGGATGATGGTGTT
CAAAAACCTGACGATTCGTGCGCGCATCGGTTTTACGATGGCGTTTCTGGCGGTGCTCCTGGCTGTGATAGGCGGGCTCG
GCGTGTACGGCATGACGCGCGCGAACGATACGACGCGCGATATTTTCACGAACCAGATGCCGAGCGCGGTCGACGTGTCG
GTGGCCGAGATCTACGCCGCACGCGAACGCCTGGCGCTCGACCGTGCGGCGCTCCTGGCCAGCACGCCGGACGCGGCAGC
CGCCGTCGAGCGAAGCCGCGCGATGCGCGCGCAGTCCGACACCTGGTGGCAGAAGTACCTTGCGTTGCCACGCGGCCCGG
AGGAAGACCGGCTTGCCCAGGACGTCGCCGCGAAGCGGCAGGCGCTGCAGCACGAGTGCGACGCGTTCGCGAGCGTGGTC
GGCGCGAATCAGGCCGACCGGATCGGCGAAGGCGCGAAGCAGCTCCAGGCGCGCTACAACGACCTTGCGACGGCGAGCGA
GGCGCTGCGCAACTTTCAGTTCACCGATGCGCAAGCCGGCTTCGATCATGCGGAATCGGCATACGACACGCTGCGCGTGC
TGGCGATCGTCGCGTTGTTGGCCGGCCTTGGCGCCGCGGTCGTGTCGTGGCTGACGCTGAGCCGCGCGATCGGCCGCCCG
ATTGCCGACGCGCTCGCGCATTTCGACGCCATTGCCGCCGGCGACCTGCGCCGGCCGATCGTCGTGGATCGCCATGACGA
GATGGGCCAGCTTCTCGAAGGCCTCGGCAAGATGCAGCGCGGGCTCGTCGACACGGTGCGCACCGTGCGCGGCGGCAGCG
AGTCGATCGCGACCGCGGCACGCCAGATTGCCGCCGGCAACATCGACCTGTCGTCGCGCACCGAGGAACAGGCCGCGGCG
CTGCAGGAAACCGCGTCGAGCATGGAGCAGCTGACCGGCACCGTGAAACAGAACGCGGACAATGCACGCCAGGCGAGTTC
GCTGGCCGCGAATGCGTCGGAGATTGCAAACAAGGGCAATACGGTAGTCGGCCAGGTGGTCGGCACGATGGGCGAGATCA
ACGACAGCTCGGCAAAGATCGCGGACATCATTGCGATCATCGAAGGAATCGCATTCCAGACCAACATTCTTGCGCTGAAT
GCAGCAGTCGAAGCTGCACGGGCAGGCGAGGAAGGCCGCGGTTTCGCGGTCGTCGCGGGCGAGGTGCGCAGCCTGGCCCA
GCGTTCGTCGACCGCGGCCAAGGAGATCAAGGTGCTGATCGACGCGTCGGTGGAGCGCATCCGGTCGGGTTCCACGCTGG
TCGACGAAGCAGGGCGCACGATGAGCGACGTGATCGGTGCGGTGCAGCGCGTGACCGACATCATGGGCGAGATCGCGGCG
GCGTCCGAGGAGCAGAGCGGCGGGATCGACCAGGTGGCGCGCGCGGTCGCGCAGATGGACGAAGTCACGCAGCAGAATGC
GGCGCTCGTCGAGGAAGCCGCGGCTGCCGCGCAATCGCTCGACGAACAGGCCGGGCGCCTGCGTGAAACGGCAGCGGTAT
TCCAGCTCAACGAAGACACGGCCCGCCCGGGTGCCGCGGCTCCGGTTGCGGTGCGTCACGCACCGCGTGCGCCCGCCGCA
GCGGTTGCGGTGCCCGTCCAGGCCGCTGCGCGCGACGAGCGCGATGCACCGCCGAGACGCGTGGCCGCAGCGGCGCCGGT
GCGCAAACCCGTCGCTGCTTCCGCTGCACCGGTGCAAACGGCCGCTACTGCTGACTCGGACGACTGGGAAACCTTCTGA

Upstream 100 bases:

>100_bases
GCTGAAGCGCGCATTTTTCATTCAGCTGTTTGTAATAAACAGACGAATAATTCGAAAAAATAGCGGAAACACCATCAAGT
TGTGCGGTGCATGGTCGTAA

Downstream 100 bases:

>100_bases
TCCGCGCGCGCCGCGCATCTATCCCCATTTGGTGACGAACGACGCCCGCGACATGCGGGCGTCGTCGTTTCTGCGTTGGA
AAAAATGTGACAGGCGACAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MHRVKQCFEATGLSRPSRRNTGRMMVFKNLTIRARIGFTMAFLAVLLAVIGGLGVYGMTRANDTTRDIFTNQMPSAVDVS
VAEIYAARERLALDRAALLASTPDAAAAVERSRAMRAQSDTWWQKYLALPRGPEEDRLAQDVAAKRQALQHECDAFASVV
GANQADRIGEGAKQLQARYNDLATASEALRNFQFTDAQAGFDHAESAYDTLRVLAIVALLAGLGAAVVSWLTLSRAIGRP
IADALAHFDAIAAGDLRRPIVVDRHDEMGQLLEGLGKMQRGLVDTVRTVRGGSESIATAARQIAAGNIDLSSRTEEQAAA
LQETASSMEQLTGTVKQNADNARQASSLAANASEIANKGNTVVGQVVGTMGEINDSSAKIADIIAIIEGIAFQTNILALN
AAVEAARAGEEGRGFAVVAGEVRSLAQRSSTAAKEIKVLIDASVERIRSGSTLVDEAGRTMSDVIGAVQRVTDIMGEIAA
ASEEQSGGIDQVARAVAQMDEVTQQNAALVEEAAAAAQSLDEQAGRLRETAAVFQLNEDTARPGAAAPVAVRHAPRAPAA
AVAVPVQAAARDERDAPPRRVAAAAPVRKPVAASAAPVQTAATADSDDWETF

Sequences:

>Translated_612_residues
MHRVKQCFEATGLSRPSRRNTGRMMVFKNLTIRARIGFTMAFLAVLLAVIGGLGVYGMTRANDTTRDIFTNQMPSAVDVS
VAEIYAARERLALDRAALLASTPDAAAAVERSRAMRAQSDTWWQKYLALPRGPEEDRLAQDVAAKRQALQHECDAFASVV
GANQADRIGEGAKQLQARYNDLATASEALRNFQFTDAQAGFDHAESAYDTLRVLAIVALLAGLGAAVVSWLTLSRAIGRP
IADALAHFDAIAAGDLRRPIVVDRHDEMGQLLEGLGKMQRGLVDTVRTVRGGSESIATAARQIAAGNIDLSSRTEEQAAA
LQETASSMEQLTGTVKQNADNARQASSLAANASEIANKGNTVVGQVVGTMGEINDSSAKIADIIAIIEGIAFQTNILALN
AAVEAARAGEEGRGFAVVAGEVRSLAQRSSTAAKEIKVLIDASVERIRSGSTLVDEAGRTMSDVIGAVQRVTDIMGEIAA
ASEEQSGGIDQVARAVAQMDEVTQQNAALVEEAAAAAQSLDEQAGRLRETAAVFQLNEDTARPGAAAPVAVRHAPRAPAA
AVAVPVQAAARDERDAPPRRVAAAAPVRKPVAASAAPVQTAATADSDDWETF
>Mature_612_residues
MHRVKQCFEATGLSRPSRRNTGRMMVFKNLTIRARIGFTMAFLAVLLAVIGGLGVYGMTRANDTTRDIFTNQMPSAVDVS
VAEIYAARERLALDRAALLASTPDAAAAVERSRAMRAQSDTWWQKYLALPRGPEEDRLAQDVAAKRQALQHECDAFASVV
GANQADRIGEGAKQLQARYNDLATASEALRNFQFTDAQAGFDHAESAYDTLRVLAIVALLAGLGAAVVSWLTLSRAIGRP
IADALAHFDAIAAGDLRRPIVVDRHDEMGQLLEGLGKMQRGLVDTVRTVRGGSESIATAARQIAAGNIDLSSRTEEQAAA
LQETASSMEQLTGTVKQNADNARQASSLAANASEIANKGNTVVGQVVGTMGEINDSSAKIADIIAIIEGIAFQTNILALN
AAVEAARAGEEGRGFAVVAGEVRSLAQRSSTAAKEIKVLIDASVERIRSGSTLVDEAGRTMSDVIGAVQRVTDIMGEIAA
ASEEQSGGIDQVARAVAQMDEVTQQNAALVEEAAAAAQSLDEQAGRLRETAAVFQLNEDTARPGAAAPVAVRHAPRAPAA
AVAVPVQAAARDERDAPPRRVAAAAPVRKPVAASAAPVQTAATADSDDWETF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=330, Percent_Identity=60.6060606060606, Blast_Score=351, Evalue=1e-97,
Organism=Escherichia coli, GI1788194, Length=534, Percent_Identity=44.5692883895131, Blast_Score=349, Evalue=4e-97,
Organism=Escherichia coli, GI2367378, Length=553, Percent_Identity=45.3887884267631, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1787690, Length=353, Percent_Identity=54.957507082153, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789453, Length=327, Percent_Identity=40.3669724770642, Blast_Score=218, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 64389; Mature: 64389

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRVKQCFEATGLSRPSRRNTGRMMVFKNLTIRARIGFTMAFLAVLLAVIGGLGVYGMTR
CCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC
ANDTTRDIFTNQMPSAVDVSVAEIYAARERLALDRAALLASTPDAAAAVERSRAMRAQSD
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCH
TWWQKYLALPRGPEEDRLAQDVAAKRQALQHECDAFASVVGANQADRIGEGAKQLQARYN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DLATASEALRNFQFTDAQAGFDHAESAYDTLRVLAIVALLAGLGAAVVSWLTLSRAIGRP
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
IADALAHFDAIAAGDLRRPIVVDRHDEMGQLLEGLGKMQRGLVDTVRTVRGGSESIATAA
HHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RQIAAGNIDLSSRTEEQAAALQETASSMEQLTGTVKQNADNARQASSLAANASEIANKGN
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCC
TVVGQVVGTMGEINDSSAKIADIIAIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
EVRSLAQRSSTAAKEIKVLIDASVERIRSGSTLVDEAGRTMSDVIGAVQRVTDIMGEIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ASEEQSGGIDQVARAVAQMDEVTQQNAALVEEAAAAAQSLDEQAGRLRETAAVFQLNEDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
ARPGAAAPVAVRHAPRAPAAAVAVPVQAAARDERDAPPRRVAAAAPVRKPVAASAAPVQT
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCHH
AATADSDDWETF
HCCCCCCCCCCC
>Mature Secondary Structure
MHRVKQCFEATGLSRPSRRNTGRMMVFKNLTIRARIGFTMAFLAVLLAVIGGLGVYGMTR
CCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC
ANDTTRDIFTNQMPSAVDVSVAEIYAARERLALDRAALLASTPDAAAAVERSRAMRAQSD
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCH
TWWQKYLALPRGPEEDRLAQDVAAKRQALQHECDAFASVVGANQADRIGEGAKQLQARYN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DLATASEALRNFQFTDAQAGFDHAESAYDTLRVLAIVALLAGLGAAVVSWLTLSRAIGRP
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
IADALAHFDAIAAGDLRRPIVVDRHDEMGQLLEGLGKMQRGLVDTVRTVRGGSESIATAA
HHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RQIAAGNIDLSSRTEEQAAALQETASSMEQLTGTVKQNADNARQASSLAANASEIANKGN
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCC
TVVGQVVGTMGEINDSSAKIADIIAIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
EVRSLAQRSSTAAKEIKVLIDASVERIRSGSTLVDEAGRTMSDVIGAVQRVTDIMGEIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ASEEQSGGIDQVARAVAQMDEVTQQNAALVEEAAAAAQSLDEQAGRLRETAAVFQLNEDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
ARPGAAAPVAVRHAPRAPAAAVAVPVQAAARDERDAPPRRVAAAAPVRKPVAASAAPVQT
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCHH
AATADSDDWETF
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]