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The map label for this gene is rbsK [H]

Identifier: 78066219

GI number: 78066219

Start: 1740760

End: 1741689

Strand: Direct

Name: rbsK [H]

Synonym: Bcep18194_A4749

Alternate gene names: 78066219

Gene position: 1740760-1741689 (Clockwise)

Preceding gene: 78066218

Following gene: 78066220

Centisome position: 47.12

GC content: 73.44

Gene sequence:

>930_bases
ATGACGGCGCCCGCAGCACACACCGGCCGCGTGACGGTGGTCGGCAGCCTCAACATGGATCTGGTCGTGCGCGCGCCGCG
TCTGCCGCTGCCGGGCGAAACGCTCGCCGGTCATGCGTTCGCGCAGGCGGCGGGCGGCAAGGGCGGCAACCAGGCCGTCG
CGGCCGCACGGCTCGGCGCGCAGGTCGCGATGATCGGCTGCGTCGGCGCGGATGCACACGGCGCGGCGCTGCGCGCGAGC
CTCGAAGCCGAGGGGATCGACTGCGCGGGGCTCGCGACGAGCGCGTCGGCGTCGACCGGCGTCGCGCTGATCGTCGTCGA
CGATGCGAGCCAGAACGCGATCGTGATCGTCGCGGGCGGCAATGGCGAGGTCACGACCGAGACGGTCGCACGGCACGAAG
CCGCACTGGCGTCGGCCGATGTGCTGATCTGCCAGCTCGAGACGCCGCCGGAGGCCGTGTTCGCGGCGCTGTCGGCCGGA
CGTCGGCTCGGCCGCACTGTGGTGCTCAATCCGGCCCCGGCCGTCGCACCACTGCCGGACGGCTGGCTGCCGCTCGTCGA
TTACCTGATCCCGAACGAGGTCGAGGCGGCCGCGCTGACCGCGCTGCCGGTACGCGATCCGGCAGAGGCGGAAGCCGCCG
CACGCGTGCTGCAGGCCGGCGGCGCATGCAATGTGCTGGTGACGCTGGGCGCGCGCGGCGTGCTTGCGCTGACGGCCGAT
GGCGCGGCACGGCATTATCCGGCGCCGGCCGTGCAGGCCGTCGACACGACGGCGGCCGGCGATACCTTCATCGGCGGTTT
TTCCGCGCGCCTCGCGGCCGGCGCGGATGTCGACACGGCCATCCGCTTCGCGCAACGCGCAGCGGCCCTGTCGGTCACGC
GCGCGGGCGCGCAGCCGTCAATTCCAACGCTTGCCGAACTGACCGAATAG

Upstream 100 bases:

>100_bases
CGACCGCCGTGCCGAGCCGCCGTCGCGTCGTGTCGCCGCGCCTCGTGCTGCGCGAATCGACGGCGATCTACCGCGAGCCG
CCGGCATCGGGCGGTCGCGC

Downstream 100 bases:

>100_bases
GGCTGGATCACGCGTCGCGGCTGGTTCGTCGCCAACGACGGCCGGCCGCGTATCTGCGACGCTCGCCGGCAGCGGAGCAC
CTCCCATCACCTCGCTTCCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTAPAAHTGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRAS
LEAEGIDCAGLATSASASTGVALIVVDDASQNAIVIVAGGNGEVTTETVARHEAALASADVLICQLETPPEAVFAALSAG
RRLGRTVVLNPAPAVAPLPDGWLPLVDYLIPNEVEAAALTALPVRDPAEAEAAARVLQAGGACNVLVTLGARGVLALTAD
GAARHYPAPAVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQRAAALSVTRAGAQPSIPTLAELTE

Sequences:

>Translated_309_residues
MTAPAAHTGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRAS
LEAEGIDCAGLATSASASTGVALIVVDDASQNAIVIVAGGNGEVTTETVARHEAALASADVLICQLETPPEAVFAALSAG
RRLGRTVVLNPAPAVAPLPDGWLPLVDYLIPNEVEAAALTALPVRDPAEAEAAARVLQAGGACNVLVTLGARGVLALTAD
GAARHYPAPAVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQRAAALSVTRAGAQPSIPTLAELTE
>Mature_308_residues
TAPAAHTGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRASL
EAEGIDCAGLATSASASTGVALIVVDDASQNAIVIVAGGNGEVTTETVARHEAALASADVLICQLETPPEAVFAALSAGR
RLGRTVVLNPAPAVAPLPDGWLPLVDYLIPNEVEAAALTALPVRDPAEAEAAARVLQAGGACNVLVTLGARGVLALTADG
AARHYPAPAVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQRAAALSVTRAGAQPSIPTLAELTE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=40.2027027027027, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=44.1860465116279, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082343, Length=293, Percent_Identity=31.3993174061433, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789775, Length=261, Percent_Identity=29.1187739463602, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=38.1107491856677, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=31.3253012048193, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322565, Length=276, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=39.8671096345515, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24583886, Length=298, Percent_Identity=33.2214765100671, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30483; Mature: 30352

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPAAHTGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGA
CCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHCC
QVAMIGCVGADAHGAALRASLEAEGIDCAGLATSASASTGVALIVVDDASQNAIVIVAGG
EEEEEEEECCCCCCCEEEEECCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEEECC
NGEVTTETVARHEAALASADVLICQLETPPEAVFAALSAGRRLGRTVVLNPAPAVAPLPD
CCCEEHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
GWLPLVDYLIPNEVEAAALTALPVRDPAEAEAAARVLQAGGACNVLVTLGARGVLALTAD
CHHHHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEC
GAARHYPAPAVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQRAAALSVTRAGAQPS
CCCCCCCCCHHHHCCCCCCCCCEECCCHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCC
IPTLAELTE
CCCHHHHCC
>Mature Secondary Structure 
TAPAAHTGRVTVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGA
CCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHCC
QVAMIGCVGADAHGAALRASLEAEGIDCAGLATSASASTGVALIVVDDASQNAIVIVAGG
EEEEEEEECCCCCCCEEEEECCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEEECC
NGEVTTETVARHEAALASADVLICQLETPPEAVFAALSAGRRLGRTVVLNPAPAVAPLPD
CCCEEHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
GWLPLVDYLIPNEVEAAALTALPVRDPAEAEAAARVLQAGGACNVLVTLGARGVLALTAD
CHHHHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEC
GAARHYPAPAVQAVDTTAAGDTFIGGFSARLAAGADVDTAIRFAQRAAALSVTRAGAQPS
CCCCCCCCCHHHHCCCCCCCCCEECCCHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCC
IPTLAELTE
CCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]