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The map label for this gene is ychM [C]

Identifier: 78066149

GI number: 78066149

Start: 1670759

End: 1672489

Strand: Direct

Name: ychM [C]

Synonym: Bcep18194_A4679

Alternate gene names: 78066149

Gene position: 1670759-1672489 (Clockwise)

Preceding gene: 78066148

Following gene: 78066156

Centisome position: 45.23

GC content: 68.92

Gene sequence:

>1731_bases
ATGACGACCGCCCCGATCCGCCCCGATGCCGGCCCGCAGCATGCCGACCATTTCGCCGCGCTCGACGCGGCCTCGCCGCC
GCCCACGCGACGTATCGGCCTCGATGCGCTGGCCGGCTTGTCGATCGCGGGCCTGCTGATCCCCGAGGCGGTCGCGTATG
CGGGGCTGGCGAACCTGCCGCCGCAGGCCGGTCTCATCGCGTTGCTGTCGGGGCTCGTCGTCTATGCGCTCACCGGCAGC
AGCCGCTTCGCGATCGTGTCGTCGACGTCGTCGTCGGCCGCCGTGCTCGCGGCGACCGTGCTCGCGGAATCGGGGATGGC
GCTTGCCGCACAGCTCGCGCTCGCCGCCGCGCTCGTCGCAATGACGGGCGTGCTGTTCATCCTGGCGGGTGCCGCGCGGC
TCGGCGGCATGTCGGATTTCGTCGCGCGGCCGGTGCTGCGCGGCTTCACGTTCGGCCTCGCGCTGACGATCGTCATCAAG
CAGTTGCCGAAGATTCTCGCGATCTCCGTGCAGCACAGCGATGCGCCGCATGTCGCGCTCGACCTGATCACCGGCGCACC
GCATGCGAATCTCGCGAGCGTCGTGCTCGGCGCGATCGCACTGGCGTTGCTGTTCGCGCTCGGGCGGAGCTCGCGCGTGC
CCGCGACGCTCGTCGTGATCGTGCTGTCGATCGCGGCCGGCTATGCGATCGACTGGCAGCGATACGGGATCGCGATCGTC
GGCCATATCGATTTCAAGCATATCGAGTTCGGCCTGCCGACCCTCGACCGCAACGCGTGGATGCAGACCATCGAGCTTGC
ATTCGCGCTGATGCTGATCCTGTACGCGGAATCGTACGGATCGATCCGCAACTTCGCGTTGAAGCACGGCGACAGCGTGT
CGCCGAACCGCGACCTCGTCGCGCTCGGCTGTGCGAATCTCGTATCGGGCCTGCTGCACGGGATGCCGGTCGGCGCCGGG
TATTCGGCGACCTCGGCGAACGAAGCGGCCGGTGCGCAGTCGCGCTTTGCCGGCCTGTGGGCGGCGGGTGTGGTCGCGCT
GATCGTCTGGCTGCTGCTGCCGCAGCTCGCGCGCACGCCGGAGCCCGTGCTCGCGGCGATCGTGATCTTCGCGGTCAGCC
ACTCGCTGCATCCGTCGGTATTCCGGCCGTACTGGGCCTGGCATCGCGACCGGCTCGTCGTGATCGCCGCGCTGCTCGCG
GTGCTCGTGCTCGGGGTGCTGCACGGGCTGCTCGCGGCCATCGGCGTGAGCCTGCTGCTGACGCTGCGCAAGCTGTCCGA
ACCGAACGTCAGCGTGCTCGGCAGGCTGCGCGACAGTCACGATTTCGTCGACGTGGCGAGCCATGCCGATGCGAAGCCGG
TGCCGGGCGTGCTGATCGTACGGCCCGAGGCGCAACTGTTCTTCGCGAATGCGGACCGGATGCTGAACCGCGTGCGTGCG
CTGATGAAGGCCGCGCCTGACGCGCATACCGTGATGCTGAGCCTCGAGGAAACGCCGGATGTCGACAGCACGACGATCGA
ATCGTTGCGCACGTTCGCAGCCGAATGCACGGCGCGCGGGTTGCGGCTCGCCATCGTGCGGCTCAAGGTGCACGCACTGC
ATGCGTTGCGCCGGGCGGCCGACGATACGCTGCACGACAATGCAATGTCCGAACTGAGCGTCGACGAGAGCCTGCAACTG
CTGCAGGCCGGGATGCCGCCGGACGGCAGCGACGGCACGACCGCCGCGTGA

Upstream 100 bases:

>100_bases
GCGAAGGCGCTCGATATCGCATTGCATCGTGCGCATGAGCAGGATGCACGCTATCTGCCCGGCTGGTCGGGCGTCATCGC
CGTCAAGCCCTGACCCCCTC

Downstream 100 bases:

>100_bases
CGAGGCGGCGCGCCGGCCCGTGCTATTGCGAAACTGCGGCGTCGGCGGAGCGATCGATCATGTCGGTCACTTCGGCCGCT
GTCGGCGCATAGGCGCCTGC

Product: Sulfate transporter/antisigma-factor antagonist STAS

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MTTAPIRPDAGPQHADHFAALDAASPPPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGS
SRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVAMTGVLFILAGAARLGGMSDFVARPVLRGFTFGLALTIVIK
QLPKILAISVQHSDAPHVALDLITGAPHANLASVVLGAIALALLFALGRSSRVPATLVVIVLSIAAGYAIDWQRYGIAIV
GHIDFKHIEFGLPTLDRNAWMQTIELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQSRFAGLWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLA
VLVLGVLHGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
LMKAAPDAHTVMLSLEETPDVDSTTIESLRTFAAECTARGLRLAIVRLKVHALHALRRAADDTLHDNAMSELSVDESLQL
LQAGMPPDGSDGTTAA

Sequences:

>Translated_576_residues
MTTAPIRPDAGPQHADHFAALDAASPPPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGS
SRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVAMTGVLFILAGAARLGGMSDFVARPVLRGFTFGLALTIVIK
QLPKILAISVQHSDAPHVALDLITGAPHANLASVVLGAIALALLFALGRSSRVPATLVVIVLSIAAGYAIDWQRYGIAIV
GHIDFKHIEFGLPTLDRNAWMQTIELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQSRFAGLWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLA
VLVLGVLHGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
LMKAAPDAHTVMLSLEETPDVDSTTIESLRTFAAECTARGLRLAIVRLKVHALHALRRAADDTLHDNAMSELSVDESLQL
LQAGMPPDGSDGTTAA
>Mature_575_residues
TTAPIRPDAGPQHADHFAALDAASPPPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGSS
RFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVAMTGVLFILAGAARLGGMSDFVARPVLRGFTFGLALTIVIKQ
LPKILAISVQHSDAPHVALDLITGAPHANLASVVLGAIALALLFALGRSSRVPATLVVIVLSIAAGYAIDWQRYGIAIVG
HIDFKHIEFGLPTLDRNAWMQTIELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLVALGCANLVSGLLHGMPVGAGY
SATSANEAAGAQSRFAGLWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLAV
LVLGVLHGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRAL
MKAAPDAHTVMLSLEETPDVDSTTIESLRTFAAECTARGLRLAIVRLKVHALHALRRAADDTLHDNAMSELSVDESLQLL
QAGMPPDGSDGTTAA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721255, Length=459, Percent_Identity=27.2331154684096, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI94721253, Length=459, Percent_Identity=27.2331154684096, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI94721257, Length=459, Percent_Identity=27.2331154684096, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI94721259, Length=459, Percent_Identity=27.2331154684096, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI217272867, Length=509, Percent_Identity=24.3614931237721, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI16418413, Length=509, Percent_Identity=24.3614931237721, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI39752683, Length=481, Percent_Identity=23.0769230769231, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI45827800, Length=481, Percent_Identity=23.0769230769231, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI47131207, Length=506, Percent_Identity=26.4822134387352, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI20336272, Length=506, Percent_Identity=26.4822134387352, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI269784651, Length=478, Percent_Identity=22.8033472803347, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4557535, Length=515, Percent_Identity=24.4660194174757, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI45827802, Length=439, Percent_Identity=22.3234624145786, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI100913030, Length=491, Percent_Identity=22.6069246435845, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4505697, Length=485, Percent_Identity=21.2371134020619, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI20336282, Length=490, Percent_Identity=21.8367346938776, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI16306483, Length=490, Percent_Identity=21.8367346938776, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI262206105, Length=138, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI262206075, Length=138, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI262206069, Length=138, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI262206063, Length=138, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI16418457, Length=530, Percent_Identity=21.6981132075472, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI301601599, Length=530, Percent_Identity=21.6981132075472, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI65506789, Length=375, Percent_Identity=27.2, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081859, Length=217, Percent_Identity=26.7281105990783, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17551690, Length=510, Percent_Identity=24.7058823529412, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI86564196, Length=495, Percent_Identity=22.2222222222222, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17566848, Length=572, Percent_Identity=24.6503496503496, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI86565215, Length=505, Percent_Identity=23.3663366336634, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86564876, Length=524, Percent_Identity=20.9923664122137, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193203292, Length=493, Percent_Identity=22.920892494929, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562578, Length=518, Percent_Identity=21.6216216216216, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325260, Length=555, Percent_Identity=21.6216216216216, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319771, Length=449, Percent_Identity=22.9398663697105, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24649801, Length=540, Percent_Identity=24.2592592592593, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24651449, Length=446, Percent_Identity=25.5605381165919, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24666186, Length=516, Percent_Identity=25.1937984496124, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922482, Length=505, Percent_Identity=22.5742574257426, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24663084, Length=441, Percent_Identity=26.0770975056689, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357695, Length=441, Percent_Identity=26.0770975056689, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21358633, Length=569, Percent_Identity=22.3198594024605, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358229, Length=168, Percent_Identity=31.547619047619, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85815873, Length=142, Percent_Identity=31.6901408450704, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24647160, Length=283, Percent_Identity=20.1413427561837, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60175; Mature: 60044

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPIRPDAGPQHADHFAALDAASPPPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVA
CCCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MTGVLFILAGAARLGGMSDFVARPVLRGFTFGLALTIVIKQLPKILAISVQHSDAPHVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
DLITGAPHANLASVVLGAIALALLFALGRSSRVPATLVVIVLSIAAGYAIDWQRYGIAIV
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEE
GHIDFKHIEFGLPTLDRNAWMQTIELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLV
EECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQSRFAGLWAAGVVALIVWLLLPQLARTP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLAVLVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
HHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LMKAAPDAHTVMLSLEETPDVDSTTIESLRTFAAECTARGLRLAIVRLKVHALHALRRAA
HHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DDTLHDNAMSELSVDESLQLLQAGMPPDGSDGTTAA
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTAPIRPDAGPQHADHFAALDAASPPPTRRIGLDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVA
CCCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MTGVLFILAGAARLGGMSDFVARPVLRGFTFGLALTIVIKQLPKILAISVQHSDAPHVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
DLITGAPHANLASVVLGAIALALLFALGRSSRVPATLVVIVLSIAAGYAIDWQRYGIAIV
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEE
GHIDFKHIEFGLPTLDRNAWMQTIELAFALMLILYAESYGSIRNFALKHGDSVSPNRDLV
EECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQSRFAGLWAAGVVALIVWLLLPQLARTP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLAVLVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
HHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LMKAAPDAHTVMLSLEETPDVDSTTIESLRTFAAECTARGLRLAIVRLKVHALHALRRAA
HHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DDTLHDNAMSELSVDESLQLLQAGMPPDGSDGTTAA
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]