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The map label for this gene is yfeR [H]

Identifier: 78066106

GI number: 78066106

Start: 1615843

End: 1616745

Strand: Direct

Name: yfeR [H]

Synonym: Bcep18194_A4635

Alternate gene names: 78066106

Gene position: 1615843-1616745 (Clockwise)

Preceding gene: 78066103

Following gene: 78066107

Centisome position: 43.74

GC content: 68.66

Gene sequence:

>903_bases
ATGAACGTCACGCTGCGCCAGCTTCGCGTCTTCATCGAGGTAGCGCGGCTCAAGAGCTTCAGTCGCGCGGGCGACGAGAT
CGGGCTCACGCAGTCCGCGGTCAGTCGCTGCGTGCGCGAGCTCGAGGCCGAGCTCGGGTTGAAGCTGATCGATCGCACGA
CGCGCGACGTGCAGCTGACCGATGTTGGGGCGAACCTGATCGCGAGCGTGTCCCGTCTGCTCGACGATCTCGACGACACG
CTGCGCGAGATTCGCGAGATCGGTGAGCAGCGCCGCGGGCGGGTGATCGTCGCGGCCAGCCCGACGATCGCGTGCCGGCT
GATGCCGCGCGTGGTTGCGTCGTGCGAGCGCCAGTTTCCGTTCGTGACGTTGGGTTTACGCGACGACGTGCAGAGCGACG
TGTTGCGCAAGGTGAAGTCGAGCGAGGTCGACTTCGGCGTCGTGATCGGTCCGCTCGCGGTGGCCGATCTCGTCTGCGAA
TCGTTGATGACCGATTCGTTCTGCCTTGTTGCGCGCGCCGACCATCCGCTCGCGGCGCGTGCCGAGGTGCCCTGGACGGC
GCTGGACGGCGAGCGCCTCGTGCTCCTCGATCATGCGTCGGGAAGCCGGCCGCTGATCGATGCCGCGCTGGCCGCCCATC
GTGTCAACGCGACGGTCATGCAGGAGCTCGGGCATTCGGCGACCGTGTTCGGCCTCGTCGAGGCCGGCGTCGGTGTAAGC
GTGCAGCCGTGGCTGTCGCTGCCGCTACCTGCCGGCTCGACGCTCGTTGCACGGCCGCTCACGCCGCGCACCGAGCGCAC
GGTCGAACTCGTGCGCCGCCGCGACCGGTCGTTGTCGCCCGCTGCGCAAGCGATCTGGGAACTCGTGCGGCAGATGCCGG
CGAGGGCGGAGGACCTCGACTGA

Upstream 100 bases:

>100_bases
CCGCAGCGAAACATGTGGGGCAGGTGCCTGATTCGTACATCGAAGCCGGATTCGCGCATTAAAATCGCGCATCGATATCG
ACGATTGATGAGGTCAGGAA

Downstream 100 bases:

>100_bases
CGCCCGCCGACGTGCGCCTCTCCGGCTTGCGGGCCGGTACACTACGCGGATCGTGTTCCTCGAAGGTGGTGCTCGATGGC
GTATTCCGCAGATTCTTTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNVTLRQLRVFIEVARLKSFSRAGDEIGLTQSAVSRCVRELEAELGLKLIDRTTRDVQLTDVGANLIASVSRLLDDLDDT
LREIREIGEQRRGRVIVAASPTIACRLMPRVVASCERQFPFVTLGLRDDVQSDVLRKVKSSEVDFGVVIGPLAVADLVCE
SLMTDSFCLVARADHPLAARAEVPWTALDGERLVLLDHASGSRPLIDAALAAHRVNATVMQELGHSATVFGLVEAGVGVS
VQPWLSLPLPAGSTLVARPLTPRTERTVELVRRRDRSLSPAAQAIWELVRQMPARAEDLD

Sequences:

>Translated_300_residues
MNVTLRQLRVFIEVARLKSFSRAGDEIGLTQSAVSRCVRELEAELGLKLIDRTTRDVQLTDVGANLIASVSRLLDDLDDT
LREIREIGEQRRGRVIVAASPTIACRLMPRVVASCERQFPFVTLGLRDDVQSDVLRKVKSSEVDFGVVIGPLAVADLVCE
SLMTDSFCLVARADHPLAARAEVPWTALDGERLVLLDHASGSRPLIDAALAAHRVNATVMQELGHSATVFGLVEAGVGVS
VQPWLSLPLPAGSTLVARPLTPRTERTVELVRRRDRSLSPAAQAIWELVRQMPARAEDLD
>Mature_300_residues
MNVTLRQLRVFIEVARLKSFSRAGDEIGLTQSAVSRCVRELEAELGLKLIDRTTRDVQLTDVGANLIASVSRLLDDLDDT
LREIREIGEQRRGRVIVAASPTIACRLMPRVVASCERQFPFVTLGLRDDVQSDVLRKVKSSEVDFGVVIGPLAVADLVCE
SLMTDSFCLVARADHPLAARAEVPWTALDGERLVLLDHASGSRPLIDAALAAHRVNATVMQELGHSATVFGLVEAGVGVS
VQPWLSLPLPAGSTLVARPLTPRTERTVELVRRRDRSLSPAAQAIWELVRQMPARAEDLD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=51.3793103448276, Blast_Score=286, Evalue=8e-79,
Organism=Escherichia coli, GI145693105, Length=290, Percent_Identity=31.3793103448276, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=30.1038062283737, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788481, Length=284, Percent_Identity=30.9859154929577, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=28.6852589641434, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788887, Length=289, Percent_Identity=23.8754325259516, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790399, Length=296, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788297, Length=295, Percent_Identity=25.7627118644068, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787601, Length=195, Percent_Identity=27.6923076923077, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786401, Length=176, Percent_Identity=34.0909090909091, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=29.9435028248588, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789204, Length=285, Percent_Identity=27.719298245614, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=238, Percent_Identity=25.2100840336134, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787128, Length=186, Percent_Identity=26.8817204301075, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786508, Length=146, Percent_Identity=26.7123287671233, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=244, Percent_Identity=27.0491803278689, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=165, Percent_Identity=27.8787878787879, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=168, Percent_Identity=26.7857142857143, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790011, Length=112, Percent_Identity=29.4642857142857, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=26.2295081967213, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787589, Length=152, Percent_Identity=28.2894736842105, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787530, Length=209, Percent_Identity=24.8803827751196, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081978, Length=245, Percent_Identity=25.7142857142857, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788626, Length=248, Percent_Identity=27.0161290322581, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788296, Length=242, Percent_Identity=23.9669421487603, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32793; Mature: 32793

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTLRQLRVFIEVARLKSFSRAGDEIGLTQSAVSRCVRELEAELGLKLIDRTTRDVQLT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCEEEE
DVGANLIASVSRLLDDLDDTLREIREIGEQRRGRVIVAASPTIACRLMPRVVASCERQFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCC
FVTLGLRDDVQSDVLRKVKSSEVDFGVVIGPLAVADLVCESLMTDSFCLVARADHPLAAR
EEEECCHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
AEVPWTALDGERLVLLDHASGSRPLIDAALAAHRVNATVMQELGHSATVFGLVEAGVGVS
CCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCE
VQPWLSLPLPAGSTLVARPLTPRTERTVELVRRRDRSLSPAAQAIWELVRQMPARAEDLD
ECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNVTLRQLRVFIEVARLKSFSRAGDEIGLTQSAVSRCVRELEAELGLKLIDRTTRDVQLT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCEEEE
DVGANLIASVSRLLDDLDDTLREIREIGEQRRGRVIVAASPTIACRLMPRVVASCERQFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCC
FVTLGLRDDVQSDVLRKVKSSEVDFGVVIGPLAVADLVCESLMTDSFCLVARADHPLAAR
EEEECCHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
AEVPWTALDGERLVLLDHASGSRPLIDAALAAHRVNATVMQELGHSATVFGLVEAGVGVS
CCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCE
VQPWLSLPLPAGSTLVARPLTPRTERTVELVRRRDRSLSPAAQAIWELVRQMPARAEDLD
ECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]