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The map label for this gene is fecC [C]

Identifier: 78065963

GI number: 78065963

Start: 1458167

End: 1459207

Strand: Direct

Name: fecC [C]

Synonym: Bcep18194_A4492

Alternate gene names: 78065963

Gene position: 1458167-1459207 (Clockwise)

Preceding gene: 78065962

Following gene: 78065966

Centisome position: 39.47

GC content: 73.39

Gene sequence:

>1041_bases
ATGAGCGTGCACGTGCGTGCATCGCGGCCCGGCATGCGCGTGGTGCTGCCGGCGCTGACGCTGCTGTTGATCGTGTCGAT
CGTCGCGTCGGCCGCGTTCGGCCCGGCGCCGATCGCGATGCCGGCGGCGGTGAGGATCGTCGCCACGCACATCGTGTCGG
CGTTCGGCGACGCGGGCGCATTCGCGGCAGGGGCGGGCGACGACAGCATCGTCTGGCTGATCCGGATGCCGCGCGCGCTG
CTGGCCGCGATCGTCGGCGCGACGCTGGCCGCGGTCGGCGTGGCGCTGCAGGCGGCGACCGCGAACTGCCTGGCCGATCC
GCACCTGCTCGGCGTGAGCGCGGGCGCAATGCTCGGCGCCGTCGCGGTCACGGTGATGGCCGGCGCGGCATTCGGCCCGT
TCACGCTGTCGGCTGCCGCGTTCGCGGGCGCGCTCGCGGCGACTGCCTGCGTCGTCGCGCTTGCTTACCGGCGCGGCCGG
CTCGAGTCGGACCGGCTGCTGCTCGCCGGCGTATCGGTGTCGTTCATGATGGCCGCGTTCGGCAACCTGCTGCTGTATCT
CGGCGACCAACGCGCCGCGTCGTCGGTGCTGTTCTGGATGCTCGGCGGCGTCGGGCTCGCGCGCTGGGACCTGCTGCCGG
TGCCGGCCGTATGCGCGGTGCTCGCTGGCGGCGCGTTGTACGCGCGCCGGCGCGAACTGAATGCGCTGATGTCGGGCGAT
GTTGCCGCGGCTACGCTCGGCGTGCCGAGCGCGCGGATGCGGCGCGAGGTCTTCGTCGTCGCGTCGTTCGCGACCGGCGC
GATGGTGGCGGTGAGCGGGGCGATCGGCTTCGTCGGGCTCGTGACGCCGCACCTGTGCCGTCGTGTCGTCGGCGCCGAGC
ACGGCAGGCTGCTGCCGGTGGCCGCGCTGACCGGTGCGATCCTGCTCGTCTGGGCCGATGTGGCCGCTCGCACGCTCGCG
GCACCGGAGGATCTGCCGATCGGGATCGTGACCGCGATGTTCGGCAGCCTGTTCTTCGTCGCGCTGCTGCGCCGCCACTG
A

Upstream 100 bases:

>100_bases
TGATTCCGTACGATGCGGCGACGCCGGGCCCCGAGAACGTCGCGGCCGTCGAGACGCTCGCGCGCGCGCTGTATCCGGCC
GCGTTCGCGGGGCCGGCGCG

Downstream 100 bases:

>100_bases
GCGGCGCGCAGGTCAGGCGAGGGCGGCCAGGGCGCGTCCTGCCGCGCGCTTCATTGCCGCGGGATGGCCATGCCGGCGCT
GCCGCCGAACGTGTCGAGAT

Product: ABC Fe3+ siderophore transporter, inner membrane subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSVHVRASRPGMRVVLPALTLLLIVSIVASAAFGPAPIAMPAAVRIVATHIVSAFGDAGAFAAGAGDDSIVWLIRMPRAL
LAAIVGATLAAVGVALQAATANCLADPHLLGVSAGAMLGAVAVTVMAGAAFGPFTLSAAAFAGALAATACVVALAYRRGR
LESDRLLLAGVSVSFMMAAFGNLLLYLGDQRAASSVLFWMLGGVGLARWDLLPVPAVCAVLAGGALYARRRELNALMSGD
VAAATLGVPSARMRREVFVVASFATGAMVAVSGAIGFVGLVTPHLCRRVVGAEHGRLLPVAALTGAILLVWADVAARTLA
APEDLPIGIVTAMFGSLFFVALLRRH

Sequences:

>Translated_346_residues
MSVHVRASRPGMRVVLPALTLLLIVSIVASAAFGPAPIAMPAAVRIVATHIVSAFGDAGAFAAGAGDDSIVWLIRMPRAL
LAAIVGATLAAVGVALQAATANCLADPHLLGVSAGAMLGAVAVTVMAGAAFGPFTLSAAAFAGALAATACVVALAYRRGR
LESDRLLLAGVSVSFMMAAFGNLLLYLGDQRAASSVLFWMLGGVGLARWDLLPVPAVCAVLAGGALYARRRELNALMSGD
VAAATLGVPSARMRREVFVVASFATGAMVAVSGAIGFVGLVTPHLCRRVVGAEHGRLLPVAALTGAILLVWADVAARTLA
APEDLPIGIVTAMFGSLFFVALLRRH
>Mature_345_residues
SVHVRASRPGMRVVLPALTLLLIVSIVASAAFGPAPIAMPAAVRIVATHIVSAFGDAGAFAAGAGDDSIVWLIRMPRALL
AAIVGATLAAVGVALQAATANCLADPHLLGVSAGAMLGAVAVTVMAGAAFGPFTLSAAAFAGALAATACVVALAYRRGRL
ESDRLLLAGVSVSFMMAAFGNLLLYLGDQRAASSVLFWMLGGVGLARWDLLPVPAVCAVLAGGALYARRRELNALMSGDV
AAATLGVPSARMRREVFVVASFATGAMVAVSGAIGFVGLVTPHLCRRVVGAEHGRLLPVAALTGAILLVWADVAARTLAA
PEDLPIGIVTAMFGSLFFVALLRRH

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=35.4838709677419, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=36.7132867132867, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=36.5853658536585, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1786805, Length=282, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1786804, Length=274, Percent_Identity=32.4817518248175, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786347, Length=315, Percent_Identity=31.1111111111111, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35065; Mature: 34934

Theoretical pI: Translated: 11.23; Mature: 11.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHVRASRPGMRVVLPALTLLLIVSIVASAAFGPAPIAMPAAVRIVATHIVSAFGDAGA
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
FAAGAGDDSIVWLIRMPRALLAAIVGATLAAVGVALQAATANCLADPHLLGVSAGAMLGA
EECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VAVTVMAGAAFGPFTLSAAAFAGALAATACVVALAYRRGRLESDRLLLAGVSVSFMMAAF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
GNLLLYLGDQRAASSVLFWMLGGVGLARWDLLPVPAVCAVLAGGALYARRRELNALMSGD
HHHHEEECCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCC
VAAATLGVPSARMRREVFVVASFATGAMVAVSGAIGFVGLVTPHLCRRVVGAEHGRLLPV
HHHHHCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
AALTGAILLVWADVAARTLAAPEDLPIGIVTAMFGSLFFVALLRRH
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVHVRASRPGMRVVLPALTLLLIVSIVASAAFGPAPIAMPAAVRIVATHIVSAFGDAGA
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
FAAGAGDDSIVWLIRMPRALLAAIVGATLAAVGVALQAATANCLADPHLLGVSAGAMLGA
EECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VAVTVMAGAAFGPFTLSAAAFAGALAATACVVALAYRRGRLESDRLLLAGVSVSFMMAAF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
GNLLLYLGDQRAASSVLFWMLGGVGLARWDLLPVPAVCAVLAGGALYARRRELNALMSGD
HHHHEEECCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCC
VAAATLGVPSARMRREVFVVASFATGAMVAVSGAIGFVGLVTPHLCRRVVGAEHGRLLPV
HHHHHCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
AALTGAILLVWADVAARTLAAPEDLPIGIVTAMFGSLFFVALLRRH
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]