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The map label for this gene is speB [H]

Identifier: 78065850

GI number: 78065850

Start: 1337072

End: 1338040

Strand: Direct

Name: speB [H]

Synonym: Bcep18194_A4379

Alternate gene names: 78065850

Gene position: 1337072-1338040 (Clockwise)

Preceding gene: 78065848

Following gene: 78065851

Centisome position: 36.19

GC content: 66.25

Gene sequence:

>969_bases
ATGAGCCAGAACGATTTCGCATTCACGCGCGACAGCCTCTACGGCACGCAGGCCGAGCCGACCTTCGCGGGCGCGACGAG
CTTCATGCGCCGGCGCTTCAGCCGCGACCTCGACGGCGTCGATCTCGCGATCACCGGCGTGCCGTTCGATTCCGCCGCAT
CGCACCGGCCCGGCACGCGCTTCGGCCCGCGCGGGTTGCGGATCGCGTCGACGGGCATCGCGTGGGAGCGCCCGTGGCCG
TGGTCGTTCGATCCGTTCGACGTGCTGGCCGCGGTCGACTACGGCGATTGCGCATTCGATCTCGGGCAGCCCGAATCGGT
GCCGGGCGCGATCGAGCGGCATGCCGATGCGATCCTCGCGCGCGGCTGCGCGATGCTGACGCTCGGCGGCGATCACTTCA
TCACGTATCCGCTGCTGAAAGCGCATGCGAAGGTGCACGGGCCGCTGTCGCTCGTGCATTTCGATGCGCATACCGACACG
TGGCCCGATCGCGACGTGAAGCGCATCGATCACGGCACGATGTTCTATCACGCGGCGCGAGAAGGGTGGGTCGTGCCCGA
ACGATCCGCGCAGATCGGCATCCGGACGACCAACGACGAGCCGATGGGCTTCGATATCCAGGATGCGCGCCAGGTGCATG
CATCGACGCCCGCTGCGATCGCCTCACGTATTCGCGAGCGGGTCGGCGATCATCCCGTGTATCTGACGTTCGACATCGAC
TGCCTCGATCCGGCGTTCGCGCCGGGCACGGGCACGCCGGTCTCGGGTGGGCTGTCGAGCCATCAGGCATTCGAGATCCT
GCGTCACCTCGAAGGCATCAACCTGGTCGGCATGGATGTGGTCGAAGTGTCGCCGCCGTATGATCATGCGGAAATCACGT
CGCTGGCCGGCGCGACGATCGCGCTGGAGCTGATCTGCCTGTATGCATCGCGCCGGCGGCAGACCATGGAAAAATCGAAC
GATGACTGA

Upstream 100 bases:

>100_bases
GCTTATGTTAGTTCATATTTTTCGTCGGATGTCGTGACGGCAGAATCGGGCACGAGGTCGCCAGCCGCGCGGCCGTCCCC
CACCCGACAGGAATCCGACG

Downstream 100 bases:

>100_bases
ACTCACCTGGCGCAAGGCCGTTCCCGACGATGCGGCCGCGTGCATCGCACTGCGCGGCAGGACGCGCGAGAACGCATTCA
CCGAGGCACAGTTGCGCGAC

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSQNDFAFTRDSLYGTQAEPTFAGATSFMRRRFSRDLDGVDLAITGVPFDSAASHRPGTRFGPRGLRIASTGIAWERPWP
WSFDPFDVLAAVDYGDCAFDLGQPESVPGAIERHADAILARGCAMLTLGGDHFITYPLLKAHAKVHGPLSLVHFDAHTDT
WPDRDVKRIDHGTMFYHAAREGWVVPERSAQIGIRTTNDEPMGFDIQDARQVHASTPAAIASRIRERVGDHPVYLTFDID
CLDPAFAPGTGTPVSGGLSSHQAFEILRHLEGINLVGMDVVEVSPPYDHAEITSLAGATIALELICLYASRRRQTMEKSN
DD

Sequences:

>Translated_322_residues
MSQNDFAFTRDSLYGTQAEPTFAGATSFMRRRFSRDLDGVDLAITGVPFDSAASHRPGTRFGPRGLRIASTGIAWERPWP
WSFDPFDVLAAVDYGDCAFDLGQPESVPGAIERHADAILARGCAMLTLGGDHFITYPLLKAHAKVHGPLSLVHFDAHTDT
WPDRDVKRIDHGTMFYHAAREGWVVPERSAQIGIRTTNDEPMGFDIQDARQVHASTPAAIASRIRERVGDHPVYLTFDID
CLDPAFAPGTGTPVSGGLSSHQAFEILRHLEGINLVGMDVVEVSPPYDHAEITSLAGATIALELICLYASRRRQTMEKSN
DD
>Mature_321_residues
SQNDFAFTRDSLYGTQAEPTFAGATSFMRRRFSRDLDGVDLAITGVPFDSAASHRPGTRFGPRGLRIASTGIAWERPWPW
SFDPFDVLAAVDYGDCAFDLGQPESVPGAIERHADAILARGCAMLTLGGDHFITYPLLKAHAKVHGPLSLVHFDAHTDTW
PDRDVKRIDHGTMFYHAAREGWVVPERSAQIGIRTTNDEPMGFDIQDARQVHASTPAAIASRIRERVGDHPVYLTFDIDC
LDPAFAPGTGTPVSGGLSSHQAFEILRHLEGINLVGMDVVEVSPPYDHAEITSLAGATIALELICLYASRRRQTMEKSND
D

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=40.5498281786942, Blast_Score=221, Evalue=9e-58,
Organism=Escherichia coli, GI1789306, Length=273, Percent_Identity=52.3809523809524, Blast_Score=271, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 35316; Mature: 35185

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNDFAFTRDSLYGTQAEPTFAGATSFMRRRFSRDLDGVDLAITGVPFDSAASHRPGTR
CCCCCCEEEHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCC
FGPRGLRIASTGIAWERPWPWSFDPFDVLAAVDYGDCAFDLGQPESVPGAIERHADAILA
CCCCCEEEEECCCCCCCCCCCCCCHHHHEEECCCCCEEECCCCCCCCCHHHHHHHHHHHH
RGCAMLTLGGDHFITYPLLKAHAKVHGPLSLVHFDAHTDTWPDRDVKRIDHGTMFYHAAR
CCEEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHCCCEEEEEECC
EGWVVPERSAQIGIRTTNDEPMGFDIQDARQVHASTPAAIASRIRERVGDHPVYLTFDID
CCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEC
CLDPAFAPGTGTPVSGGLSSHQAFEILRHLEGINLVGMDVVEVSPPYDHAEITSLAGATI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECEEEEECCCCCCHHHHHHHHHHHH
ALELICLYASRRRQTMEKSNDD
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQNDFAFTRDSLYGTQAEPTFAGATSFMRRRFSRDLDGVDLAITGVPFDSAASHRPGTR
CCCCCEEEHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCC
FGPRGLRIASTGIAWERPWPWSFDPFDVLAAVDYGDCAFDLGQPESVPGAIERHADAILA
CCCCCEEEEECCCCCCCCCCCCCCHHHHEEECCCCCEEECCCCCCCCCHHHHHHHHHHHH
RGCAMLTLGGDHFITYPLLKAHAKVHGPLSLVHFDAHTDTWPDRDVKRIDHGTMFYHAAR
CCEEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHCCCEEEEEECC
EGWVVPERSAQIGIRTTNDEPMGFDIQDARQVHASTPAAIASRIRERVGDHPVYLTFDID
CCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEC
CLDPAFAPGTGTPVSGGLSSHQAFEILRHLEGINLVGMDVVEVSPPYDHAEITSLAGATI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECEEEEECCCCCCHHHHHHHHHHHH
ALELICLYASRRRQTMEKSNDD
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]