Click here to switch to the map view.

The map label for this gene is appY [C]

Identifier: 78065846

GI number: 78065846

Start: 1330821

End: 1331858

Strand: Direct

Name: appY [C]

Synonym: Bcep18194_A4375

Alternate gene names: 78065846

Gene position: 1330821-1331858 (Clockwise)

Preceding gene: 78065844

Following gene: 78065848

Centisome position: 36.03

GC content: 68.02

Gene sequence:

>1038_bases
ATGAATGTCTGGAACTTTGCCCGCAGCCCGGCTTCCGTCCTGCTGATGATCGACTTCGGTCGCGACCGCAAGATCGCGCC
GCCGGCGTTGCTCAAGGGGTCGCAGCTCACGCTGAAGCAGCTCGCCGACCCGGATTTCACAGTGCTGGCCGCGCAGGAGC
TGGCGGTGGCGTCGAACCTGCTCGACCTGACCGCCGGCGAGGCCGGCGTCGGCCTCAAGGTCGGGCTGTCGTACCAGCTG
TCGGCTTACGGGCTGCTCGGGTACGGGCTGCTGAGCAGCGCGACCGGCATGGACGCGATCGCGCTCGCGGGCCGCTACCT
GGCGCTGACCTATACGTTCGTCGGGATGACGTTCCACCGCGCCGGGCAGCGCGACGTGATTCAGTTCGACGCGTCGCCGG
AGCTTGCCGCGAACGTGCAGCGCTTCTTCGTCGAACGCGCGATGGGCGCGACGTGCCGGGTGCTGCGCGACGTGATCGGC
AGTGCGTTCGAACTCGCGACGTTCGATCTCGCGTATGGCGCCGGCCCCGGCGCTGACGCTGACGCTGACGCGAAGCAGCC
GGTGCTCGGCGCGATGATCCGGCACGGGCAGCCGGCCAGCACGCTCACGTTCGAGCATGCGCATCTCGAGCGGCCGTTGC
CGCAGGCGAATGCCGCGACCGCGGCGATGTGCGAGCGCATGTGTGCCGAGCTGATCACGCGCAGGCGGACGCGCGTCGAT
CTCGTTTCGTTCCTGAACGAATACCTGGCCACGCGCCCGTTCGACCGGCCGCCGCAGCTGAAGGACATCGCGACGCTGCT
CAACACCAGCGAGCGCACGTTGAAGCGCCGGCTGCAGGAAGAGGGCGCGTGCTTTCGGGACATTTCGAGCGCGGTGCGCA
AGACTCGCGCGCAGGCGCTGATCGCCGAAGGGCGGCTGTCGATCAAGGAAATCGCGCAGGAACTGGGATTCAGCGACATG
TCGTCGTTCTCGCAGGCGTACAAGCGCTGGACGGGTGTCGCGCCGAGCGTATCGCGACAGGAGACGGCCGGTTCGTAG

Upstream 100 bases:

>100_bases
TTGCGATGGCATCCATCATCGGCGCGCAGGCTCGCGCGATCCATGCTGGGGCAGGCCAACCGCTTTAGAATCTAGGCCAA
CCCACGTCGCGAGGCGTCTG

Downstream 100 bases:

>100_bases
CGCGCGTTCCGGCGGCCCGGCATCGCAGATACAGAAAAGCCCGTGAGCAAGCTGATGCTCACGGGCTTTTTCGTCGTCGC
GGCGGGGTGGGCCGGCACCG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNVWNFARSPASVLLMIDFGRDRKIAPPALLKGSQLTLKQLADPDFTVLAAQELAVASNLLDLTAGEAGVGLKVGLSYQL
SAYGLLGYGLLSSATGMDAIALAGRYLALTYTFVGMTFHRAGQRDVIQFDASPELAANVQRFFVERAMGATCRVLRDVIG
SAFELATFDLAYGAGPGADADADAKQPVLGAMIRHGQPASTLTFEHAHLERPLPQANAATAAMCERMCAELITRRRTRVD
LVSFLNEYLATRPFDRPPQLKDIATLLNTSERTLKRRLQEEGACFRDISSAVRKTRAQALIAEGRLSIKEIAQELGFSDM
SSFSQAYKRWTGVAPSVSRQETAGS

Sequences:

>Translated_345_residues
MNVWNFARSPASVLLMIDFGRDRKIAPPALLKGSQLTLKQLADPDFTVLAAQELAVASNLLDLTAGEAGVGLKVGLSYQL
SAYGLLGYGLLSSATGMDAIALAGRYLALTYTFVGMTFHRAGQRDVIQFDASPELAANVQRFFVERAMGATCRVLRDVIG
SAFELATFDLAYGAGPGADADADAKQPVLGAMIRHGQPASTLTFEHAHLERPLPQANAATAAMCERMCAELITRRRTRVD
LVSFLNEYLATRPFDRPPQLKDIATLLNTSERTLKRRLQEEGACFRDISSAVRKTRAQALIAEGRLSIKEIAQELGFSDM
SSFSQAYKRWTGVAPSVSRQETAGS
>Mature_345_residues
MNVWNFARSPASVLLMIDFGRDRKIAPPALLKGSQLTLKQLADPDFTVLAAQELAVASNLLDLTAGEAGVGLKVGLSYQL
SAYGLLGYGLLSSATGMDAIALAGRYLALTYTFVGMTFHRAGQRDVIQFDASPELAANVQRFFVERAMGATCRVLRDVIG
SAFELATFDLAYGAGPGADADADAKQPVLGAMIRHGQPASTLTFEHAHLERPLPQANAATAAMCERMCAELITRRRTRVD
LVSFLNEYLATRPFDRPPQLKDIATLLNTSERTLKRRLQEEGACFRDISSAVRKTRAQALIAEGRLSIKEIAQELGFSDM
SSFSQAYKRWTGVAPSVSRQETAGS

Specific function: Induces The Synthesis Of Acid Phosphatase (Appa) And Several Other Polypeptides (Such As Appbc) During The Deceleration Phase Of Growth. It Also Acts As A Transcriptional Repressor For One Group Of Proteins That Are Synthesized Preferentially In Exponenti

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786776, Length=165, Percent_Identity=29.6969696969697, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37395; Mature: 37395

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVWNFARSPASVLLMIDFGRDRKIAPPALLKGSQLTLKQLADPDFTVLAAQELAVASNL
CCCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCCCHHHHHHCCCCEEEHHHHHHHHHHHH
LDLTAGEAGVGLKVGLSYQLSAYGLLGYGLLSSATGMDAIALAGRYLALTYTFVGMTFHR
HHHCCCCCCCCEEECCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AGQRDVIQFDASPELAANVQRFFVERAMGATCRVLRDVIGSAFELATFDLAYGAGPGADA
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
DADAKQPVLGAMIRHGQPASTLTFEHAHLERPLPQANAATAAMCERMCAELITRRRTRVD
CCCCCCHHHHHHHHCCCCCCCEEECHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVSFLNEYLATRPFDRPPQLKDIATLLNTSERTLKRRLQEEGACFRDISSAVRKTRAQAL
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IAEGRLSIKEIAQELGFSDMSSFSQAYKRWTGVAPSVSRQETAGS
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure
MNVWNFARSPASVLLMIDFGRDRKIAPPALLKGSQLTLKQLADPDFTVLAAQELAVASNL
CCCCCCCCCCCEEEEEEECCCCCCCCCHHHCCCCCHHHHHHCCCCEEEHHHHHHHHHHHH
LDLTAGEAGVGLKVGLSYQLSAYGLLGYGLLSSATGMDAIALAGRYLALTYTFVGMTFHR
HHHCCCCCCCCEEECCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AGQRDVIQFDASPELAANVQRFFVERAMGATCRVLRDVIGSAFELATFDLAYGAGPGADA
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
DADAKQPVLGAMIRHGQPASTLTFEHAHLERPLPQANAATAAMCERMCAELITRRRTRVD
CCCCCCHHHHHHHHCCCCCCCEEECHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVSFLNEYLATRPFDRPPQLKDIATLLNTSERTLKRRLQEEGACFRDISSAVRKTRAQAL
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IAEGRLSIKEIAQELGFSDMSSFSQAYKRWTGVAPSVSRQETAGS
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12368430 [H]