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The map label for this gene is argD

Identifier: 78065763

GI number: 78065763

Start: 1229573

End: 1230805

Strand: Direct

Name: argD

Synonym: Bcep18194_A4291

Alternate gene names: 78065763

Gene position: 1229573-1230805 (Clockwise)

Preceding gene: 78065762

Following gene: 78065764

Centisome position: 33.28

GC content: 66.02

Gene sequence:

>1233_bases
ATGACGACCTCGACCGTGAACCGCCAGACATTCGATGAAGTGATGGTGCCGGTATTTTCCCCCGCGCCGTTCGTGCCGGA
TCGCGCAGAGGGCTCCCGCGTGTGGGACACGGCCGGCCGCGAATACATCGATTTCGCGTGCGGCATCGCCGTGACGTCGC
TCGGCCACGGCCACCCGGAACTGCTGAAAGTCCTGGACGAACAAAGCCGCAAGCTCTGGCACATCGGCAACGGCTACACG
AACGAGCCGGTGCTGCGCCTCGCGCAGCGCCTCGAATCGCTGACCTTCGCCGATCGCGCATTCTTCGCGAACTCGGGCGC
GGAAGCGAACGAAGCCGCACTGAAGCTCGCGCGCCGCGTCGCGTTCGATCGCCACGGCGCGGATAAAGCCGAAATCATCT
CGTTCGTGCAGTCGTTCCACGGCCGCACGTTCTTCACGGTCAGCGTCGGTGGCCAGCCGAAGTACTCGGAAGGCTTCGGC
CCCGTGCCGGCTGGCATCAAGCACCTGCCGTACAACGACATCGACGCCGCGAAGGCCGCGATCGGCCCGCAAACCTGCGC
CGTGATCGTCGAGCCCGTGCAAGGCGAAGGCGGCGTGATCCCGGCCGATCCGGCCTTCCTGAAGGCGCTGCGCGAAGCCT
GCGACGCACACGGCGCACTGCTGATTTTCGACGAAGTGCAAACGGGCGTCGGCCGCACGGGCCAGTTCTACGCTTACATG
GATACCGGCGTCACGCCGGACATCCTGACGACCGCCAAGGCGCTCGGCAACGGCTTCCCGATCGGCGCGATGCTGACGAC
GAACGAACTGGCCGCGCACTTCAAGGTCGGTGTGCACGGCACGACGTACGGCGGTAACCCGCTCGCATCGGCCATCGCCG
ACAAGGTCGTCGAACTGATCGGCGACCCGGCGCTGCTCGAAGGCGTGCGCGAACGCAGTGTGCGCCTGAAAGGCGCGCTC
GAACGCATCAACGCGCGCTTCGGCATCTTCAAGGACGTGCGCGGCAAGGGCCTGCTCGTCGGCGCCGAACTCACCGCCGC
ATTCGACGGCCGCGCGAAGGACTTCGTCACCGCAGCAGCAGAAAACGGCCTGATCATGCTGATCGCCGGCCCGAACGTGC
TGCGCTTCGTGCCGTCGCTGGTGATCCCGTTCGACCTGCTCGACGAAGGCATGAAACGCTTCGAGAAGGCAGTCGAACAA
GTGCTCGCCGCTCAGGAAGCCACCGCGCGCTGA

Upstream 100 bases:

>100_bases
CGCTTCCGATAGAACCCGTCGCAATTCCGCAAGACGCTTGCGTCACCCGTACCTAAACTTGATCCTGTTGAACCCTCTTA
CGAAACCGAAAGGAACGACC

Downstream 100 bases:

>100_bases
TCGGCGCACCCATCGCAGACAGGAACGACGATGCTATTTGTTCGCCCCGGCAAACTCACGGATCTCGATGCGCTCGCGCA
CATGGCGCGCACCGCGCAGC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTTSTVNRQTFDEVMVPVFSPAPFVPDRAEGSRVWDTAGREYIDFACGIAVTSLGHGHPELLKVLDEQSRKLWHIGNGYT
NEPVLRLAQRLESLTFADRAFFANSGAEANEAALKLARRVAFDRHGADKAEIISFVQSFHGRTFFTVSVGGQPKYSEGFG
PVPAGIKHLPYNDIDAAKAAIGPQTCAVIVEPVQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGQFYAYM
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLASAIADKVVELIGDPALLEGVRERSVRLKGAL
ERINARFGIFKDVRGKGLLVGAELTAAFDGRAKDFVTAAAENGLIMLIAGPNVLRFVPSLVIPFDLLDEGMKRFEKAVEQ
VLAAQEATAR

Sequences:

>Translated_410_residues
MTTSTVNRQTFDEVMVPVFSPAPFVPDRAEGSRVWDTAGREYIDFACGIAVTSLGHGHPELLKVLDEQSRKLWHIGNGYT
NEPVLRLAQRLESLTFADRAFFANSGAEANEAALKLARRVAFDRHGADKAEIISFVQSFHGRTFFTVSVGGQPKYSEGFG
PVPAGIKHLPYNDIDAAKAAIGPQTCAVIVEPVQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGQFYAYM
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLASAIADKVVELIGDPALLEGVRERSVRLKGAL
ERINARFGIFKDVRGKGLLVGAELTAAFDGRAKDFVTAAAENGLIMLIAGPNVLRFVPSLVIPFDLLDEGMKRFEKAVEQ
VLAAQEATAR
>Mature_409_residues
TTSTVNRQTFDEVMVPVFSPAPFVPDRAEGSRVWDTAGREYIDFACGIAVTSLGHGHPELLKVLDEQSRKLWHIGNGYTN
EPVLRLAQRLESLTFADRAFFANSGAEANEAALKLARRVAFDRHGADKAEIISFVQSFHGRTFFTVSVGGQPKYSEGFGP
VPAGIKHLPYNDIDAAKAAIGPQTCAVIVEPVQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGQFYAYMD
TGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLASAIADKVVELIGDPALLEGVRERSVRLKGALE
RINARFGIFKDVRGKGLLVGAELTAAFDGRAKDFVTAAAENGLIMLIAGPNVLRFVPSLVIPFDLLDEGMKRFEKAVEQV
LAAQEATAR

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=33.8541666666667, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=36.4548494983278, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI13994255, Length=446, Percent_Identity=29.372197309417, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI37574042, Length=427, Percent_Identity=27.1662763466042, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI24119277, Length=397, Percent_Identity=27.2040302267003, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI226442705, Length=427, Percent_Identity=26.2295081967213, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=27.0408163265306, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI188536080, Length=415, Percent_Identity=24.0963855421687, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI38679950, Length=415, Percent_Identity=24.0963855421687, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI38679946, Length=415, Percent_Identity=24.0963855421687, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1788044, Length=401, Percent_Identity=60.3491271820449, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789759, Length=401, Percent_Identity=56.857855361596, Blast_Score=486, Evalue=1e-139,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=35.9605911330049, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=34.4913151364764, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI145693181, Length=321, Percent_Identity=35.8255451713396, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786991, Length=418, Percent_Identity=30.1435406698565, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786349, Length=340, Percent_Identity=33.2352941176471, Blast_Score=118, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=388, Percent_Identity=34.5360824742268, Blast_Score=227, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=31.322505800464, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=258, Percent_Identity=35.2713178294574, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=28.538283062645, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=446, Percent_Identity=27.3542600896861, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71981843, Length=182, Percent_Identity=31.8681318681319, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=39.8009950248756, Blast_Score=279, Evalue=6e-76,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=32.3383084577114, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=316, Percent_Identity=28.1645569620253, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=377, Percent_Identity=26.525198938992, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21357415, Length=384, Percent_Identity=33.0729166666667, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI28574759, Length=411, Percent_Identity=30.9002433090024, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=29.9065420560748, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21356575, Length=420, Percent_Identity=29.5238095238095, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281366494, Length=439, Percent_Identity=23.9179954441913, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=439, Percent_Identity=23.9179954441913, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=439, Percent_Identity=23.9179954441913, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43865; Mature: 43733

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSTVNRQTFDEVMVPVFSPAPFVPDRAEGSRVWDTAGREYIDFACGIAVTSLGHGHPE
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCHH
LLKVLDEQSRKLWHIGNGYTNEPVLRLAQRLESLTFADRAFFANSGAEANEAALKLARRV
HHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFDRHGADKAEIISFVQSFHGRTFFTVSVGGQPKYSEGFGPVPAGIKHLPYNDIDAAKAA
HHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
IGPQTCAVIVEPVQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGQFYAYM
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEE
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLASAIADKVVELI
CCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHEEEECCEECCCCCHHHHHHHHHHHHHH
GDPALLEGVRERSVRLKGALERINARFGIFKDVRGKGLLVGAELTAAFDGRAKDFVTAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEECEEHHHCCCCHHHHHHHHC
ENGLIMLIAGPNVLRFVPSLVIPFDLLDEGMKRFEKAVEQVLAAQEATAR
CCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTSTVNRQTFDEVMVPVFSPAPFVPDRAEGSRVWDTAGREYIDFACGIAVTSLGHGHPE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCHH
LLKVLDEQSRKLWHIGNGYTNEPVLRLAQRLESLTFADRAFFANSGAEANEAALKLARRV
HHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFDRHGADKAEIISFVQSFHGRTFFTVSVGGQPKYSEGFGPVPAGIKHLPYNDIDAAKAA
HHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
IGPQTCAVIVEPVQGEGGVIPADPAFLKALREACDAHGALLIFDEVQTGVGRTGQFYAYM
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEE
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLASAIADKVVELI
CCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHEEEECCEECCCCCHHHHHHHHHHHHHH
GDPALLEGVRERSVRLKGALERINARFGIFKDVRGKGLLVGAELTAAFDGRAKDFVTAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEECEEHHHCCCCHHHHHHHHC
ENGLIMLIAGPNVLRFVPSLVIPFDLLDEGMKRFEKAVEQVLAAQEATAR
CCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]