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The map label for this gene is otsB [H]

Identifier: 78065741

GI number: 78065741

Start: 1201752

End: 1202504

Strand: Direct

Name: otsB [H]

Synonym: Bcep18194_A4269

Alternate gene names: 78065741

Gene position: 1201752-1202504 (Clockwise)

Preceding gene: 78065737

Following gene: 78065742

Centisome position: 32.53

GC content: 69.19

Gene sequence:

>753_bases
ATGCAATCCGTTCCGGCTTCCCTGTCCCTGACCGATACCGCGTTCTTCTTCGACTTCGACGGCACGCTCGTCGAGTTGGC
GCCGACGCCCGACAGCATTCATGTTCCGCCGTCGCTGCTGACGCTGCTCGACGAGCTGCAGCGCCGCTCGCACGGCGCGG
TCGCGATCGTGTCCGGGCGCGGGATCGACAACATCGACACGTTCCTGAAGATGCCCGACATGCCGATCGCCGGCCTGCAC
GGCGCGGAGCGTCGCGATGCGAACGGCGACACGCAACGTATCGGCTTCAACGACGAACGCCTGCTGCGCATCGAGCGCGA
GCTGGCGGCCGTCGTCGACCGTCATCCGGGCATGCTGCTCGAAATCAAGGGCGCGGCCGTCGCGCTGCACTACCGCAACG
CGCCCGAGCGCGAGGCGGCGGCGCGCGCGGCCACCGAGCGCCTCGTCGCCGACTATGCCGATGCGTATGTGCTGCAGCCC
GGCAAGATGGTGTTCGAGATCAAGCCGAAAGGCGTCGACAAGGGGCGCGCGCTCGCCGCGTTCCTCGACGAGCCGCCGTT
TGCCGGCCGCGTGCCGGTGTTCGCGGGCGACGACCTGACCGACGAGAAGGGCTTCGCGGTGGTCAACGCGCGCGGCGGCC
TGTCGATCAAGGTCGGCGCGGGCGAGACGTCCGCCCGCATGCGGCTCGATTCGGTCGACGCGCTGCATGAGCAGATCGCG
TGCTGGCTTGGTGCGGGGCAGTCGGACGCATGA

Upstream 100 bases:

>100_bases
TTTCGCCCATCTCGATGCGCAGGCGCGGTAAGATGCGCACAATTCCATTCGCGCAGCGGCCGCCCGGCGTTTGCCGGCCG
GCCCTCACACTATCGAATCG

Downstream 100 bases:

>100_bases
GTCGCCTCATCATTGTTTCAAACCGCGTTGCGCCGATTTCGGAAGGCGAACCGGCGGCGGGTGGTCTCGCGATCGGCGTC
TACGATGCGCTGAAGGAGAC

Product: HAD family hydrolase

Products: NA

Alternate protein names: TPP; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDSIHVPPSLLTLLDELQRRSHGAVAIVSGRGIDNIDTFLKMPDMPIAGLH
GAERRDANGDTQRIGFNDERLLRIERELAAVVDRHPGMLLEIKGAAVALHYRNAPEREAAARAATERLVADYADAYVLQP
GKMVFEIKPKGVDKGRALAAFLDEPPFAGRVPVFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
CWLGAGQSDA

Sequences:

>Translated_250_residues
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDSIHVPPSLLTLLDELQRRSHGAVAIVSGRGIDNIDTFLKMPDMPIAGLH
GAERRDANGDTQRIGFNDERLLRIERELAAVVDRHPGMLLEIKGAAVALHYRNAPEREAAARAATERLVADYADAYVLQP
GKMVFEIKPKGVDKGRALAAFLDEPPFAGRVPVFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
CWLGAGQSDA
>Mature_250_residues
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDSIHVPPSLLTLLDELQRRSHGAVAIVSGRGIDNIDTFLKMPDMPIAGLH
GAERRDANGDTQRIGFNDERLLRIERELAAVVDRHPGMLLEIKGAAVALHYRNAPEREAAARAATERLVADYADAYVLQP
GKMVFEIKPKGVDKGRALAAFLDEPPFAGRVPVFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
CWLGAGQSDA

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=219, Percent_Identity=49.3150684931507, Blast_Score=206, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320279, Length=223, Percent_Identity=26.9058295964126, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920676, Length=233, Percent_Identity=28.755364806867, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221473368, Length=236, Percent_Identity=27.5423728813559, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20129307, Length=236, Percent_Identity=27.5423728813559, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24582490, Length=236, Percent_Identity=27.5423728813559, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 26870; Mature: 26870

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDSIHVPPSLLTLLDELQRRSHGAVAIVSGR
CCCCCCCEEEECEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECC
GIDNIDTFLKMPDMPIAGLHGAERRDANGDTQRIGFNDERLLRIERELAAVVDRHPGMLL
CCCCHHHHHCCCCCCEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEE
EIKGAAVALHYRNAPEREAAARAATERLVADYADAYVLQPGKMVFEIKPKGVDKGRALAA
EECCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCEEEE
FLDEPPFAGRVPVFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
ECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCEEEHHHHHHHHHHHH
CWLGAGQSDA
HHHCCCCCCC
>Mature Secondary Structure
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDSIHVPPSLLTLLDELQRRSHGAVAIVSGR
CCCCCCCEEEECEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECC
GIDNIDTFLKMPDMPIAGLHGAERRDANGDTQRIGFNDERLLRIERELAAVVDRHPGMLL
CCCCHHHHHCCCCCCEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEE
EIKGAAVALHYRNAPEREAAARAATERLVADYADAYVLQPGKMVFEIKPKGVDKGRALAA
EECCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCEEEE
FLDEPPFAGRVPVFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
ECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCEEEHHHHHHHHHHHH
CWLGAGQSDA
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]