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The map label for this gene is pdxJ

Identifier: 78065721

GI number: 78065721

Start: 1183585

End: 1184361

Strand: Direct

Name: pdxJ

Synonym: Bcep18194_A4249

Alternate gene names: 78065721

Gene position: 1183585-1184361 (Clockwise)

Preceding gene: 78065720

Following gene: 78065722

Centisome position: 32.04

GC content: 67.05

Gene sequence:

>777_bases
ATGAGCTTCTTCCTGACAACGCCCACCGCCATCGACCTCGGCGTGAACATCGACCACGTCGCGACGCTGCGCAATGTGCG
CGGCACGACCTATCCCGATCCGATCCGCGCGGCGCTCGCTGCGGAAGAAGCCGGTGCGGATGCGATCACGCTGCACCTGC
GCGAGGATCGCCGCCACATCGTCGACGCGGATGTGCGCAAGCTGCGTCCGCTGCTGAAGACGCGCATGAACCTCGAATGC
GCGGTGACGACCGAGATGCTCGATATCGCATGCGAAGTGCGCCCGCACGACGCGTGCCTCGTGCCTGAGAAGCGCGAGGA
ACTGACGACCGAAGGCGGTCTCGATGTCGCCGGCCACTTCGAGGCCGTGCGTGCGGCATGCAAGCAGCTTGCCGACGTGG
GCGTGCGCGTGTCGCTGTTCATCGACCCGGACGAGACGCAGATCCGTGCCGCGCACGAAGCAGGCGCGCCGGTGATCGAG
CTGCATACGGGCCGTTACGCGGAAGCGCACGACGAAGCCGAGCAGCAGCGCGAATACGAGCGCATCGTCGCGGGCGTTCA
GGCCGGCGCGCAGCTCGGCCTGAAGGTCAATGCCGGTCACGGCCTGCACTACACGAACGTGCAGCAGATCGCCGCGATCG
ACGGCATCGTCGAACTGAACATCGGCCACGCGATCGTCGCGCACGCGATTTTCGCGGGCTGGGACAACGCGGTGCGCGAA
ATGAAGGCGATCATGGTTGCCGCACGCGTAGCCGCGCTGCACGGCGGCGCGCGCTGA

Upstream 100 bases:

>100_bases
CGGTTGCGCAAAGCAAGACGCTGATGCGCTTCCTGCTGAACACCTATCTCGGCGGTACGCCGCTTGCCACGCGTCAGATC
CTGATCGACCTGCAAAATCT

Downstream 100 bases:

>100_bases
AGATGAAGTGCCGCCGCGCGTCGCGCGTCATGCCTGACCCGGCCCGGCCGGGTCGCACCGGCGCGTACTGACATGGCGAT
CTATGGCATCGGTACCGACA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSFFLTTPTAIDLGVNIDHVATLRNVRGTTYPDPIRAALAAEEAGADAITLHLREDRRHIVDADVRKLRPLLKTRMNLEC
AVTTEMLDIACEVRPHDACLVPEKREELTTEGGLDVAGHFEAVRAACKQLADVGVRVSLFIDPDETQIRAAHEAGAPVIE
LHTGRYAEAHDEAEQQREYERIVAGVQAGAQLGLKVNAGHGLHYTNVQQIAAIDGIVELNIGHAIVAHAIFAGWDNAVRE
MKAIMVAARVAALHGGAR

Sequences:

>Translated_258_residues
MSFFLTTPTAIDLGVNIDHVATLRNVRGTTYPDPIRAALAAEEAGADAITLHLREDRRHIVDADVRKLRPLLKTRMNLEC
AVTTEMLDIACEVRPHDACLVPEKREELTTEGGLDVAGHFEAVRAACKQLADVGVRVSLFIDPDETQIRAAHEAGAPVIE
LHTGRYAEAHDEAEQQREYERIVAGVQAGAQLGLKVNAGHGLHYTNVQQIAAIDGIVELNIGHAIVAHAIFAGWDNAVRE
MKAIMVAARVAALHGGAR
>Mature_257_residues
SFFLTTPTAIDLGVNIDHVATLRNVRGTTYPDPIRAALAAEEAGADAITLHLREDRRHIVDADVRKLRPLLKTRMNLECA
VTTEMLDIACEVRPHDACLVPEKREELTTEGGLDVAGHFEAVRAACKQLADVGVRVSLFIDPDETQIRAAHEAGAPVIEL
HTGRYAEAHDEAEQQREYERIVAGVQAGAQLGLKVNAGHGLHYTNVQQIAAIDGIVELNIGHAIVAHAIFAGWDNAVREM
KAIMVAARVAALHGGAR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=237, Percent_Identity=65.4008438818565, Blast_Score=306, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_BURS3 (Q39I70)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_368490.1
- ProteinModelPortal:   Q39I70
- SMR:   Q39I70
- STRING:   Q39I70
- GeneID:   3749444
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A4249
- NMPDR:   fig|269483.3.peg.5469
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BioCyc:   BSP36773:BCEP18194_A4249-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 27944; Mature: 27813

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: ACT_SITE 52-52 ACT_SITE 79-79 ACT_SITE 200-200 BINDING 16-16 BINDING 27-27 BINDING 54-54 BINDING 59-59 BINDING 109-109 BINDING 201-201

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFLTTPTAIDLGVNIDHVATLRNVRGTTYPDPIRAALAAEEAGADAITLHLREDRRHI
CCEEEECCCEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHH
VDADVRKLRPLLKTRMNLECAVTTEMLDIACEVRPHDACLVPEKREELTTEGGLDVAGHF
HHHHHHHHHHHHHHHCCCEEEEHHHHHHHHEECCCCCCEECCCHHHHHCCCCCCCHHHHH
EAVRAACKQLADVGVRVSLFIDPDETQIRAAHEAGAPVIELHTGRYAEAHDEAEQQREYE
HHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
RIVAGVQAGAQLGLKVNAGHGLHYTNVQQIAAIDGIVELNIGHAIVAHAIFAGWDNAVRE
HHHHHHHCCCEECEEEECCCCCEECCHHHHHHHCCEEEECCCHHHHHHHHHHCHHHHHHH
MKAIMVAARVAALHGGAR
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFFLTTPTAIDLGVNIDHVATLRNVRGTTYPDPIRAALAAEEAGADAITLHLREDRRHI
CEEEECCCEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHH
VDADVRKLRPLLKTRMNLECAVTTEMLDIACEVRPHDACLVPEKREELTTEGGLDVAGHF
HHHHHHHHHHHHHHHCCCEEEEHHHHHHHHEECCCCCCEECCCHHHHHCCCCCCCHHHHH
EAVRAACKQLADVGVRVSLFIDPDETQIRAAHEAGAPVIELHTGRYAEAHDEAEQQREYE
HHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
RIVAGVQAGAQLGLKVNAGHGLHYTNVQQIAAIDGIVELNIGHAIVAHAIFAGWDNAVRE
HHHHHHHCCCEECEEEECCCCCEECCHHHHHHHCCEEEECCCHHHHHHHHHHCHHHHHHH
MKAIMVAARVAALHGGAR
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA