BacMap

Definition	Burkholderia sp. 383 chromosome 1, complete genome.
Accession	NC_007510
Length	3,694,126

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The map label for this gene is ydfG [H]

Identifier: 78065368

GI number: 78065368

Start: 809985

End: 810731

Strand: Reverse

Name: ydfG [H]

Synonym: Bcep18194_A3894

Alternate gene names: 78065368

Gene position: 810731-809985 (Counterclockwise)

Preceding gene: 78065376

Following gene: 78065367

Centisome position: 21.95

GC content: 68.27

Gene sequence:

>747_bases
ATGATCGTGTTCGTCACAGGCGCGTCCGCCGGCTTCGGCGCCGCCATCGCCCGTGCCTTCGTCAAGGGAGGCCACCGCGT
CGTCGCGACCGCGCGCCGCAAGGATCGCCTCGATGCGCTCGCCGCCGAACTCGGCGATTCCCTTCTGCCGCTCGAGCTCG
ACGTCCGCGATCGCGCGGCCGTCGAGGCCGTGCCGGCCGCCCTTCCCGCCGAATTCGCGGCGCTCGACGTGCTCGTCAAC
AACGCCGGCCTCGCGCTCGGCGTCGAGCCGGCCCAAAAGGCCAGCCTCGACGAATGGCACACGATGATCGACACGAACTG
CACGGGCCTCGTCACGGTCACGCACGCGCTGCTGCCCGGCATGATCGATCGCGGCCGCGGTCACGTCTTCAATATCGGCT
CGGTCGCGGGTTCGTACCCTTATGCGGGCGGCAACGTCTACGGCGCGACCAAGGCTTTCGTCAGACAATTCAGCCTGAAC
CTGCGCGCCGACCTGCTCGGCACGCCGCTGCGCGTCACCGACATCGAGCCTGGCCTGTGCGGCGGCACCGAATTCTCGAA
CATCCGCTATCGCGGCGACGACGCCAAAGCGGCGAACGTCTACAACAATGTCCAGCCGCTGATGCCCGAGGACATCGCCG
ACACGATCTACTGGATCGCGACGCGTCCGGCGCATGTGAACGTCAACACGATCGAGCTGATGCCGATCGCGCAAGCCCCG
GGCGGCCCGACCGTCCACCGCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCCCGTGCGGGAACGCTTTGCCGCCTTGCCGCGGTGCGGCAATCTCAGTAGGCTTGCGGGATACCACTCGCTATTTT
GTTATCGACCAGGAGCAGCA

Downstream 100 bases:

>100_bases
AGCCACGCGGGCCGGCCCCTTCCGGGCCGGCCCGCAGTGTGCTACGGCATACTACATTCCGTTACGAATCGGTTACGAAT
CAGGCTCCTGCCTTCCGGTA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIVFVTGASAGFGAAIARAFVKGGHRVVATARRKDRLDALAAELGDSLLPLELDVRDRAAVEAVPAALPAEFAALDVLVN
NAGLALGVEPAQKASLDEWHTMIDTNCTGLVTVTHALLPGMIDRGRGHVFNIGSVAGSYPYAGGNVYGATKAFVRQFSLN
LRADLLGTPLRVTDIEPGLCGGTEFSNIRYRGDDAKAANVYNNVQPLMPEDIADTIYWIATRPAHVNVNTIELMPIAQAP
GGPTVHRG

Sequences:

>Translated_248_residues
MIVFVTGASAGFGAAIARAFVKGGHRVVATARRKDRLDALAAELGDSLLPLELDVRDRAAVEAVPAALPAEFAALDVLVN
NAGLALGVEPAQKASLDEWHTMIDTNCTGLVTVTHALLPGMIDRGRGHVFNIGSVAGSYPYAGGNVYGATKAFVRQFSLN
LRADLLGTPLRVTDIEPGLCGGTEFSNIRYRGDDAKAANVYNNVQPLMPEDIADTIYWIATRPAHVNVNTIELMPIAQAP
GGPTVHRG
>Mature_248_residues
MIVFVTGASAGFGAAIARAFVKGGHRVVATARRKDRLDALAAELGDSLLPLELDVRDRAAVEAVPAALPAEFAALDVLVN
NAGLALGVEPAQKASLDEWHTMIDTNCTGLVTVTHALLPGMIDRGRGHVFNIGSVAGSYPYAGGNVYGATKAFVRQFSLN
LRADLLGTPLRVTDIEPGLCGGTEFSNIRYRGDDAKAANVYNNVQPLMPEDIADTIYWIATRPAHVNVNTIELMPIAQAP
GGPTVHRG

Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=32.258064516129, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=34.5744680851064, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI40548397, Length=179, Percent_Identity=33.5195530726257, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI214010158, Length=179, Percent_Identity=33.5195530726257, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI214010156, Length=179, Percent_Identity=33.5195530726257, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI22758144, Length=179, Percent_Identity=33.5195530726257, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI7657478, Length=183, Percent_Identity=36.6120218579235, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI150247226, Length=178, Percent_Identity=34.8314606741573, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=31.7204301075269, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI22507405, Length=178, Percent_Identity=32.5842696629214, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=30.0518134715026, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI157739938, Length=186, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI19743808, Length=178, Percent_Identity=28.6516853932584, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI4557649, Length=178, Percent_Identity=28.6516853932584, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI19923817, Length=188, Percent_Identity=26.063829787234, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI10190704, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI32483357, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI40254992, Length=178, Percent_Identity=28.6516853932584, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI50726952, Length=180, Percent_Identity=32.7777777777778, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787820, Length=247, Percent_Identity=63.5627530364373, Blast_Score=347, Evalue=3e-97,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=32.6530612244898, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786812, Length=240, Percent_Identity=27.9166666666667, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082100, Length=180, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082160, Length=179, Percent_Identity=27.3743016759777, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=239, Percent_Identity=25.9414225941423, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=246, Percent_Identity=26.0162601626016, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=243, Percent_Identity=25.5144032921811, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=245, Percent_Identity=26.9387755102041, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=246, Percent_Identity=27.6422764227642, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=239, Percent_Identity=26.7782426778243, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=246, Percent_Identity=27.2357723577236, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=238, Percent_Identity=23.9495798319328, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=184, Percent_Identity=27.7173913043478, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=188, Percent_Identity=27.1276595744681, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=236, Percent_Identity=24.1525423728814, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17557780, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=190, Percent_Identity=28.4210526315789, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=26.5560165975104, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=36.1788617886179, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=25.6281407035176, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=33.8645418326693, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI281364494, Length=248, Percent_Identity=31.8548387096774, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21358495, Length=184, Percent_Identity=32.0652173913043, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=36.0215053763441, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=241, Percent_Identity=30.2904564315353, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643142, Length=176, Percent_Identity=32.9545454545455, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357041, Length=182, Percent_Identity=30.2197802197802, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI116007234, Length=251, Percent_Identity=31.8725099601594, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=30.1960784313725, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI161076933, Length=179, Percent_Identity=29.608938547486, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24584748, Length=179, Percent_Identity=29.608938547486, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24663911, Length=247, Percent_Identity=28.3400809716599, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=29.7435897435897, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=29.6, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571387, Length=250, Percent_Identity=28, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648693, Length=249, Percent_Identity=28.1124497991968, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355889, Length=249, Percent_Identity=28.1124497991968, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574402, Length=180, Percent_Identity=29.4444444444444, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=180, Percent_Identity=29.4444444444444, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=29.4736842105263, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI116007232, Length=186, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26167; Mature: 26167

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFVTGASAGFGAAIARAFVKGGHRVVATARRKDRLDALAAELGDSLLPLELDVRDRAA
CEEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCHHH
VEAVPAALPAEFAALDVLVNNAGLALGVEPAQKASLDEWHTMIDTNCTGLVTVTHALLPG
HHHHCCCCCHHHHHEEEEECCCCEEEECCCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHH
MIDRGRGHVFNIGSVAGSYPYAGGNVYGATKAFVRQFSLNLRADLLGTPLRVTDIEPGLC
HHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCC
GGTEFSNIRYRGDDAKAANVYNNVQPLMPEDIADTIYWIATRPAHVNVNTIELMPIAQAP
CCCCCCCEEEECCCCCHHHHHCCCCCCCCHHHHHHEEEEEECCCEECCEEEEEEEECCCC
GGPTVHRG
CCCCCCCC
>Mature Secondary Structure
MIVFVTGASAGFGAAIARAFVKGGHRVVATARRKDRLDALAAELGDSLLPLELDVRDRAA
CEEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCHHH
VEAVPAALPAEFAALDVLVNNAGLALGVEPAQKASLDEWHTMIDTNCTGLVTVTHALLPG
HHHHCCCCCHHHHHEEEEECCCCEEEECCCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHH
MIDRGRGHVFNIGSVAGSYPYAGGNVYGATKAFVRQFSLNLRADLLGTPLRVTDIEPGLC
HHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCC
GGTEFSNIRYRGDDAKAANVYNNVQPLMPEDIADTIYWIATRPAHVNVNTIELMPIAQAP
CCCCCCCEEEECCCCCHHHHHCCCCCCCCHHHHHHEEEEEECCCEECCEEEEEEEECCCC
GGPTVHRG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]