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The map label for this gene is glk [H]

Identifier: 78065221

GI number: 78065221

Start: 635606

End: 636454

Strand: Reverse

Name: glk [H]

Synonym: Bcep18194_A3745

Alternate gene names: 78065221

Gene position: 636454-635606 (Counterclockwise)

Preceding gene: 78065226

Following gene: 78065211

Centisome position: 17.23

GC content: 69.61

Gene sequence:

>849_bases
ATGCTGCCCCGCATTGAAGCGATCCGCGCCGAGTTGCGCCCGTCCGAGCGCAAGCTCGCCGACTACATCCTCGCCGCGCC
GCGCGAGGTGCTCGACCTCGCGATGACCGAGCTGTCGACGCGCGCGGGCGTCAGCCAGCCGACGATCGCCCGGTTCTGCC
AGGCGCTCGGCTGCAGCGGCTTTCGCGAGTTCAAGATCCGGCTCGCACAGAGCGTCGCGCCCGGCGTGTCGTCGGTCTAT
CGCGACGTCGAGCCCGACGAGCCGGCGCCCGGCATCATCGGCAAGGTGTTCGACCGCACGATCGGCGCACTGATCGAGGT
GCGCAACAGCCTGTCCGCGGGCAGCGTCGCCGATGCGATCGCGCTGCTGTCGAACGCATCGCGGATCGAGTTCTACGGCG
CCGGCGGCTCGGGCATCGCCGCGCAGGACATCCAGCACAAGTTCTTCCGGCTCGGCGTGCCGAGCGTCGCCTATTCGGAT
CCGCACACGTTCTCGATGTCGTCCGCACTGCTCGGGCCACACGACGTCGTCGTCGCGATCTCGAACACCGGCCGCACGCG
CGACATCGTCGACGCCGCACGCTCCGCGCTCGCATGCGGCGCGAAGGTCGTCGCGATCACGCAGAGCCATTCGCCGCTCG
CGAAGCTCGCGACGGTCAGTCTCGCGTCGAACGTTGCGGAGGAAACGGACGTGTTCTCGCCGATGACGTCGCGGATGTCG
CATCTCGCGATCGGCGACATCCTCGCGGTCGGCGTCGCGCTGTCGCGCGGCCCTGCGCTGATGGAACGGGTCGGCCGCGC
GAAGGAAGCGATCACGCGCCGCCGGATCGACGACGGCGCGAAGGACTGA

Upstream 100 bases:

>100_bases
ATAAAAAGCATCGCGTCAGCGCTAGCATTTTCTTGTAGATTTTCTACAATTCGATTGCGATACACTCGCTCATCCGAACC
CGATTTCTGCCTGCCGTCCC

Downstream 100 bases:

>100_bases
GCCGGCACCGCGCCGACCACGTCGAGCGCGCGTAAACGACAAACGGCGCCCCGCGGGGCGCCGTTTTGCATCAGGCGACG
CCTGCAACCTCGCAGGCCTT

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Glucokinase; Glucose kinase; Putative HTH-type transcriptional regulator [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MLPRIEAIRAELRPSERKLADYILAAPREVLDLAMTELSTRAGVSQPTIARFCQALGCSGFREFKIRLAQSVAPGVSSVY
RDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVADAIALLSNASRIEFYGAGGSGIAAQDIQHKFFRLGVPSVAYSD
PHTFSMSSALLGPHDVVVAISNTGRTRDIVDAARSALACGAKVVAITQSHSPLAKLATVSLASNVAEETDVFSPMTSRMS
HLAIGDILAVGVALSRGPALMERVGRAKEAITRRRIDDGAKD

Sequences:

>Translated_282_residues
MLPRIEAIRAELRPSERKLADYILAAPREVLDLAMTELSTRAGVSQPTIARFCQALGCSGFREFKIRLAQSVAPGVSSVY
RDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVADAIALLSNASRIEFYGAGGSGIAAQDIQHKFFRLGVPSVAYSD
PHTFSMSSALLGPHDVVVAISNTGRTRDIVDAARSALACGAKVVAITQSHSPLAKLATVSLASNVAEETDVFSPMTSRMS
HLAIGDILAVGVALSRGPALMERVGRAKEAITRRRIDDGAKD
>Mature_282_residues
MLPRIEAIRAELRPSERKLADYILAAPREVLDLAMTELSTRAGVSQPTIARFCQALGCSGFREFKIRLAQSVAPGVSSVY
RDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVADAIALLSNASRIEFYGAGGSGIAAQDIQHKFFRLGVPSVAYSD
PHTFSMSSALLGPHDVVVAISNTGRTRDIVDAARSALACGAKVVAITQSHSPLAKLATVSLASNVAEETDVFSPMTSRMS
HLAIGDILAVGVALSRGPALMERVGRAKEAITRRRIDDGAKD

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=278, Percent_Identity=39.568345323741, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI87082369, Length=252, Percent_Identity=29.7619047619048, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082130, Length=210, Percent_Identity=31.9047619047619, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788767, Length=280, Percent_Identity=26.7857142857143, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836
- InterPro:   IPR000843
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02685 Glucokinase; PF01418 HTH_6; PF01380 SIS [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 29808; Mature: 29808

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRIEAIRAELRPSERKLADYILAAPREVLDLAMTELSTRAGVSQPTIARFCQALGCSG
CCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
FREFKIRLAQSVAPGVSSVYRDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVADAI
HHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALLSNASRIEFYGAGGSGIAAQDIQHKFFRLGVPSVAYSDPHTFSMSSALLGPHDVVVAI
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEEE
SNTGRTRDIVDAARSALACGAKVVAITQSHSPLAKLATVSLASNVAEETDVFSPMTSRMS
CCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAIGDILAVGVALSRGPALMERVGRAKEAITRRRIDDGAKD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLPRIEAIRAELRPSERKLADYILAAPREVLDLAMTELSTRAGVSQPTIARFCQALGCSG
CCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
FREFKIRLAQSVAPGVSSVYRDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVADAI
HHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALLSNASRIEFYGAGGSGIAAQDIQHKFFRLGVPSVAYSDPHTFSMSSALLGPHDVVVAI
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEEE
SNTGRTRDIVDAARSALACGAKVVAITQSHSPLAKLATVSLASNVAEETDVFSPMTSRMS
CCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAIGDILAVGVALSRGPALMERVGRAKEAITRRRIDDGAKD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA