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The map label for this gene is coaE

Identifier: 78065136

GI number: 78065136

Start: 546246

End: 546854

Strand: Reverse

Name: coaE

Synonym: Bcep18194_A3660

Alternate gene names: 78065136

Gene position: 546854-546246 (Counterclockwise)

Preceding gene: 78065137

Following gene: 78065135

Centisome position: 14.8

GC content: 67.98

Gene sequence:

>609_bases
ATGTTCGCAATCGGACTCACCGGCGGCATCGGCAGCGGCAAGACGACCGTCGCCGACCTGTTCGGCGCCCGCGGCGCGTC
GCTGGTCGATACCGATCTGATCGCCCATCGCATTACCGCACCGGGCGGCCTCGCGATGCCCGCGATCGAACAGGCATTCG
GTCGCGGCTTCGTTGCCGCCGACGGCTCGCTCGATCGTGCGAAGATGCGCACACTGATCTTCAGCGACGACGCCGCGCTC
CGCCGCCTCGAAGCGATCACGCACCCGCTGATCCGCGCGGAGACCGATCGCGAAGCGCGCGAAGCGCCGGGCCCGTACGT
GATGTTCGTCGTGCCGCTGCTCGTCGAGTCAGGCAACTGGAAGGCGCGCAGCGATCGCGTGCTCGTCGTCGATTGCCCGG
TCGAAACGCAGATTGCACGCGTGATGCGGCGCAACGGCTTCACGCGCGAGCAGGTCGAAGCGATCATCGCGAAACAGGCA
ACGCGCGAAGCCCGTCTCGCGGCGGCCGACGACGTGATCGTCAACGACGCGACGACACCCGACGCGCTCGCCGCGCAAGT
CGATGCATTGCACCAACGCTATCTCGGGTTTGCGGCCGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
CGCTTCGAGGAGCCGATTCCGTTCGGCCCGTTCCTCGCGGCAGGCGGCGTCGCGACGCTGTTTTTCGGCACCCCTTTCTA
TTCGGCGCTCGGAGGCTGAC

Downstream 100 bases:

>100_bases
ACCTCGCGCCCAATCGTGATGGTGTACGAAATTGGCGCGTTGCTAGGGTAGAGAGTGAGCATTAGAATGTCCTGCATTGT
TTCAATCCCTACCCAAGAGG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MFAIGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGRGFVAADGSLDRAKMRTLIFSDDAAL
RRLEAITHPLIRAETDREAREAPGPYVMFVVPLLVESGNWKARSDRVLVVDCPVETQIARVMRRNGFTREQVEAIIAKQA
TREARLAAADDVIVNDATTPDALAAQVDALHQRYLGFAAAAR

Sequences:

>Translated_202_residues
MFAIGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGRGFVAADGSLDRAKMRTLIFSDDAAL
RRLEAITHPLIRAETDREAREAPGPYVMFVVPLLVESGNWKARSDRVLVVDCPVETQIARVMRRNGFTREQVEAIIAKQA
TREARLAAADDVIVNDATTPDALAAQVDALHQRYLGFAAAAR
>Mature_202_residues
MFAIGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGRGFVAADGSLDRAKMRTLIFSDDAAL
RRLEAITHPLIRAETDREAREAPGPYVMFVVPLLVESGNWKARSDRVLVVDCPVETQIARVMRRNGFTREQVEAIIAKQA
TREARLAAADDVIVNDATTPDALAAQVDALHQRYLGFAAAAR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=34.6938775510204, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=34.6938775510204, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI110227607, Length=193, Percent_Identity=28.4974093264249, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI110227605, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227603, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227601, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI205277394, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=49.4949494949495, Blast_Score=179, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17554944, Length=208, Percent_Identity=30.2884615384615, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320402, Length=201, Percent_Identity=32.8358208955224, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24658602, Length=176, Percent_Identity=30.6818181818182, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=25.9459459459459, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_BURS3 (Q39JV5)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_367905.1
- ProteinModelPortal:   Q39JV5
- SMR:   Q39JV5
- STRING:   Q39JV5
- GeneID:   3748843
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A3660
- NMPDR:   fig|269483.3.peg.5202
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- ProtClustDB:   PRK00081
- BioCyc:   BSP36773:BCEP18194_A3660-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 21597; Mature: 21597

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAIGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGRGFVAA
CEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEE
DGSLDRAKMRTLIFSDDAALRRLEAITHPLIRAETDREAREAPGPYVMFVVPLLVESGNW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEHHHHHCCCCC
KARSDRVLVVDCPVETQIARVMRRNGFTREQVEAIIAKQATREARLAAADDVIVNDATTP
CCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
DALAAQVDALHQRYLGFAAAAR
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFAIGLTGGIGSGKTTVADLFGARGASLVDTDLIAHRITAPGGLAMPAIEQAFGRGFVAA
CEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEE
DGSLDRAKMRTLIFSDDAALRRLEAITHPLIRAETDREAREAPGPYVMFVVPLLVESGNW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEHHHHHCCCCC
KARSDRVLVVDCPVETQIARVMRRNGFTREQVEAIIAKQATREARLAAADDVIVNDATTP
CCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
DALAAQVDALHQRYLGFAAAAR
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA