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The map label for this gene is mraY

Identifier: 78065118

GI number: 78065118

Start: 526140

End: 527309

Strand: Direct

Name: mraY

Synonym: Bcep18194_A3642

Alternate gene names: 78065118

Gene position: 526140-527309 (Clockwise)

Preceding gene: 78065117

Following gene: 78065119

Centisome position: 14.24

GC content: 62.91

Gene sequence:

>1170_bases
ATGCTGCTGGCGCTGGCGCAATGGCTGCAAGGAGACGCAAGCTTTTTGCGCTTGTTCACGTACCTCACGTTCCGTGCGGT
GATGGCCACCATCACCGCGCTCGGGATCGGGCTCGTGTGCGGACCGTGGGTGATCCGCAAGCTGACGCAAATGAAGGTCG
GTCAGGCCGTGCGCAAGGACGGCCCGCAGACGCACCTGGTCAAGTCCGGCACGCCGACAATGGGCGGCGTGCTGATCCTG
ATCGGTATCGCGGTCGCGACGCTGCTGTGGGGCGACCTGACGAACCGTTTCATCTGGATCGTGATGCTCGTGACGTTCGG
TTTCGGCGTGATCGGCTGGGTCGATGATTACCGCAAGGTCGTCCACAAGGACCCGCGCGGGATGTCGTCGCGCGAGAAGT
ATTTCTGGCAATCGGTGATCGGGCTGTTCGCGGCCGTCTACCTCGCCTTCAGCGTGTCCGAGGCGAACAACGTGCGCGTG
TTCGACCTGTTCATGGCATGGGTGAGGAGCGGCCTGTCGATGGGCTTGCCGGCACGCGCCGACCTGATGCTGCCGTTCCT
GAAGTCGATCAGCTATCCGCTCGGCGTGTGGGGCTTCATCGTGCTGACGTACTTCGTGATCGTCGGCGCGAGCAACGCGG
TGAACCTGACCGACGGCCTCGACGGCCTCGTGATCATGCCGGTCGTGCTGGTCGGTGCGTCGCTGGGTGTGTTCGCGTAC
GTGATGGGCAGCGCGGTCTATTCAAAATACCTGCTGTTCCCGCACATTCCGGGCGCGGGCGAATTGCTGATCTTCTGTTC
CGCGATGGGTGGGGCAGGGCTCGCGTTCCTCTGGTACAACACGCACCCCGCGCAGGTGTTCATGGGCGACGTCGGCGCGC
TGGCGCTCGGCGGCGCGCTCGGCACGGTCGCGGTGATCGTGCGCCAGGAAATCGTGCTGTTCATCATGGGCGGCATCTTC
GTCGCGGAAACGCTGTCGGTGATGCTGCAGGTTTCGTGGTTCAAGTACACGAAGAAGCGCTACGGCGAAGGGCGTCGCCT
GCTGAAGATGGCGCCGCTGCATCACCATTTCGAATTGTCCGGCTGGAAGGAAACGCAAGTGGTCGTGCGTTTCTGGATCA
TCACGCTGATGCTGTGCCTGTTCGGTCTGACCACCCTCAAGCTGCGGTAA

Upstream 100 bases:

>100_bases
GGCTCGCGGTACATGAAGATGGAGCGCGTGGTCGACGCGCTGACGAACCAACCCGCGGCGGGCACTGCGCCCGCTGCACA
CTGAGTAGAAGGAAGGAAGC

Downstream 100 bases:

>100_bases
AGGAAAGGTAACAAGGATGTCTGGCGAGATGTTTGGAGATCGGCAACGGCCGATGGTGCTCGTACTGGGGCTCGGGGAAT
CGGGTCTCGCGATCGCGCGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVHKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLTTLKLR

Sequences:

>Translated_389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVHKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLTTLKLR
>Mature_389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVHKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLTTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=389, Percent_Identity=51.6709511568123, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 42809; Mature: 42809

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA