Click here to switch to the map view.

The map label for this gene is rocA [H]

Identifier: 78065106

GI number: 78065106

Start: 504183

End: 505889

Strand: Reverse

Name: rocA [H]

Synonym: Bcep18194_A3630

Alternate gene names: 78065106

Gene position: 505889-504183 (Counterclockwise)

Preceding gene: 78065110

Following gene: 78065105

Centisome position: 13.69

GC content: 66.55

Gene sequence:

>1707_bases
ATGACCCATGCACTGTTCACGAAGCACGAAGACACGCTGAAACACGCACTCGCCGCCATCGAGAGCCGCGGGTACTGGAG
CCCGTTCGCCGAAATGCCGAGCCCCAAAGTGTACGGGGAAAGCGCGAACGCAGATGGCGAGGCCGCGTTCAAGTCGCACC
TCGACAAGACGTTCGCGCTCGACCAGCCAGCGTCCGGAGAAACGGTCGGCGCAGAGCGGTCGCCGTACGGCGTTGCACTG
GGCATCCGGTATCCGAAGTCGACGCCCGACGAACTGATCGCCGCCGCTGCCGCCGCGCAACGCTCGTGGCGCGAAGCCGG
CCCGAGCGCCTGGATCGGCGTCAGCCTCGAAATCCTCGCGCGCCTGAATCGGGCCAGCTTCGAAATCGCCTACAGCGTGA
TGCACACCACGGGGCAGGCATTCATGATGGCGTTCCAGGCCGGCGGCCCGCACGCGCAAGATCGCGCGCTCGAGGCAGTC
GCCTATGCATGGGACGAACTGCGCCGCATCCCCGCCGAAGCACACTGGGAAAAGCCGCAAGGCAAGAACCCGCCGCTCGC
GATGCACAAGCGCTATACGATCGTCCCGCGCGGCACCGGGCTCGTGCTCGGCTGCTGCACGTTCCCGACCTGGAACGGCT
ACCCCGGCCTGTTCGCCGATCTCGCAACCGGCAACACCGTGATCGTCAAACCGCATCCGGGCGCGATCCTGCCCCTCGCC
GTCACCGTCCGGATCGCTCGCGACGTGCTGCGCGAAGCCGGTTTCGATCCGAACGTCGTCACGCTCCTCGCGACCGAACC
CAACGACGGCGCACTCGTTCAGGATCTCGCGCTGCGCCCCGAGATCAAGTTGATCGACTTCACCGGCAGCACGCAAAACG
GCACGTGGCTCGAACGCCATGCTCACCAGGCACAGGTCTATACGGAGAAGGCTGGCGTCAACCAGATCGTGATCGACTCG
ACCGACGACCTGAAGGCCGCCGCCAAAAACATCGCGTTCTCGCTGGCGCTGTACTCCGGCCAGATGTGCACGGCACCGCA
GAACATCTACGTGCCGCGCGACGGCATCCGGACGGCGGACGGCCATGCGAGCTTCGACGAGGTCGCACAGGCAATCGCCC
TTTCCGTGCAAAAACTCACCGGCGACCCGGCACGCTCGGTCGAACTGATCGGCGCAATCCAGAACGAAGGCGTGACCGCA
CGCATCGACGATGCCCGCCAGCTCGGCCGCGTGCTCGCCGACAGCCTGACCCTCCAACACCCTGCGTTCCCCGATGCCCG
CGTGCGCACGCCGCTCGTGCTGCAACTCGACGTGGCCGATCGCGAGAAATTCACGCAGGAATGGTTCGGCCCGATCTCGT
TCGTGATCGCGACCGACTCGACCGTGCAATCGCTCGACCTCGCCGGGGAAATCGCGGCGGAACATGGCGCGCTGACGCTC
TCCGTCTACAGCACCGACGATGCGATCGTCGACGCCGCCCACGACGCGGCGGTGCGCGGTGGCGTCGCGCTGTCGATCAA
CCTGACGGGCGGTGTGTTCGTGAACCAGTCGGCAGCGTTCTCGGATTTCCACGGCACGGGCGCGAACCCTGCAGCCAACG
CGGCGCTGGCCGACCCGGCGTTCGTCGCCAACCGGTTCCGCGTGGTGCAAAGCCGCGTCCATGTTGCCCCGAAGGCTGCA
CCTGTGGAAGCCGGCCAGCCGGCATAA

Upstream 100 bases:

>100_bases
ACGCCTCGCACATGCGAATAGTTTGATGCTACCATTCTCCGACCAACCGGTCGGTTAATTAATCGATCCAACCCCTCTCA
ACGTCCATCAGGCTGCCGCC

Downstream 100 bases:

>100_bases
CCCGAATGGCCGACGTGCAAACGCCGCCACGTTCTCTACCATGAACGAATCCGCCACCTGGCGGGTTCGTTGCTCATCGA
TACGCCCATGACAGACGCCT

Product: phenylacetic acid degradation protein paaN2

Products: NA

Alternate protein names: P5C dehydrogenase [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTHALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESANADGEAAFKSHLDKTFALDQPASGETVGAERSPYGVAL
GIRYPKSTPDELIAAAAAAQRSWREAGPSAWIGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWDELRRIPAEAHWEKPQGKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
VTVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERHAHQAQVYTEKAGVNQIVIDS
TDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRDGIRTADGHASFDEVAQAIALSVQKLTGDPARSVELIGAIQNEGVTA
RIDDARQLGRVLADSLTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTVQSLDLAGEIAAEHGALTL
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPAFVANRFRVVQSRVHVAPKAA
PVEAGQPA

Sequences:

>Translated_568_residues
MTHALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESANADGEAAFKSHLDKTFALDQPASGETVGAERSPYGVAL
GIRYPKSTPDELIAAAAAAQRSWREAGPSAWIGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWDELRRIPAEAHWEKPQGKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
VTVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERHAHQAQVYTEKAGVNQIVIDS
TDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRDGIRTADGHASFDEVAQAIALSVQKLTGDPARSVELIGAIQNEGVTA
RIDDARQLGRVLADSLTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTVQSLDLAGEIAAEHGALTL
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPAFVANRFRVVQSRVHVAPKAA
PVEAGQPA
>Mature_567_residues
THALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESANADGEAAFKSHLDKTFALDQPASGETVGAERSPYGVALG
IRYPKSTPDELIAAAAAAQRSWREAGPSAWIGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVA
YAWDELRRIPAEAHWEKPQGKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLAV
TVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERHAHQAQVYTEKAGVNQIVIDST
DDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRDGIRTADGHASFDEVAQAIALSVQKLTGDPARSVELIGAIQNEGVTAR
IDDARQLGRVLADSLTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTVQSLDLAGEIAAEHGALTLS
VYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPAFVANRFRVVQSRVHVAPKAAP
VEAGQPA

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17564084, Length=421, Percent_Identity=22.8028503562945, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=192, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323822, Length=327, Percent_Identity=28.1345565749235, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=341, Percent_Identity=26.6862170087977, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 60597; Mature: 60466

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESANADGEAAFKSHLDKTFAL
CCCCEECCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEECCCCCCCCHHHHHHHCCHHEEC
DQPASGETVGAERSPYGVALGIRYPKSTPDELIAAAAAAQRSWREAGPSAWIGVSLEILA
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDELRRIPAEAHWEKPQ
HHCCCHHHEEHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCC
GKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHEECCCCCEEEECCCCCCEEHHH
VTVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERH
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHH
AHQAQVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAD
HHHHHEEHHHCCCCEEEEECCHHHHHHHHHHEEEEEEECCCEECCCCCEEECCCCCCCCC
GHASFDEVAQAIALSVQKLTGDPARSVELIGAIQNEGVTARIDDARQLGRVLADSLTLQH
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCC
PAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTVQSLDLAGEIAAEHGALTL
CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEE
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPA
EEEECCCHHHCCHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH
FVANRFRVVQSRVHVAPKAAPVEAGQPA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
THALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESANADGEAAFKSHLDKTFAL
CCCEECCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEECCCCCCCCHHHHHHHCCHHEEC
DQPASGETVGAERSPYGVALGIRYPKSTPDELIAAAAAAQRSWREAGPSAWIGVSLEILA
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDELRRIPAEAHWEKPQ
HHCCCHHHEEHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCC
GKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHEECCCCCEEEECCCCCCEEHHH
VTVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERH
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHH
AHQAQVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAD
HHHHHEEHHHCCCCEEEEECCHHHHHHHHHHEEEEEEECCCEECCCCCEEECCCCCCCCC
GHASFDEVAQAIALSVQKLTGDPARSVELIGAIQNEGVTARIDDARQLGRVLADSLTLQH
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCC
PAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTVQSLDLAGEIAAEHGALTL
CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEE
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPA
EEEECCCHHHCCHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH
FVANRFRVVQSRVHVAPKAAPVEAGQPA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA