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The map label for this gene is hemA

Identifier: 78065074

GI number: 78065074

Start: 470701

End: 471999

Strand: Reverse

Name: hemA

Synonym: Bcep18194_A3598

Alternate gene names: 78065074

Gene position: 471999-470701 (Counterclockwise)

Preceding gene: 78065075

Following gene: 78065073

Centisome position: 12.78

GC content: 66.44

Gene sequence:

>1299_bases
ATGCAACTCCTCACGATCGGAATCAATCACCACACTGCGCCTGTCGCCCTGCGCGAACGCGTGGCGTTTCCGCTCGAGCA
GATCAAGCCGGCTCTCGTCACGTTCAAGAACGTGTTTCTCGGCCCGCAGGCACCCAATACGCCCGAAGCGGCGATCCTCT
CCACCTGCAACCGCACCGAACTGTATTGCGCGACAGACGATCGCGCGGCACGCGAAGGCGCGGTCCGCTGGCTGTCGGAG
TATCACCGGATTCCGGTCGACGAGCTCGCGCCGCACGTCTATGCACTGCCGCAATCGGAAGCGGTCCGGCACGCATTCCG
CGTCGCATCCGGCCTCGATTCGATGGTGCTCGGCGAAACCCAGATTCTGGGCCAGATGAAGGACGCCGTCCGCACCGCGA
CGGAAGCCGGCGCACTCGGCACCTATCTGAACCAGCTGTTCCAGCGCACGTTCGCGGTGGCGAAGGAAGTGCGCGGCACG
ACCGAAATCGGCACGCAGTCGGTGTCGATGGCCGCCGCCGCGGTGCGCCTCGCGCAACGGATCTTCGAAAAAGTGTCCGA
TCAGCGCGTGCTGTTCATCGGCGCCGGCGAGATGATCGAGCTGTGCGCCACGCACTTCGCTGCGCAAGGCCCGCGCGAAC
TCGTCGTCGCGAACCGTACGGCCGAACGCGGCCAGCGGCTTGCCGAACGCTTCAACGGCCGTGCAATGCCGCTCGCCGAT
CTGCCGACCCGCATGCACGAATTCGACATCATCGTGTCGTGCACGGCGTCGACGCTGCCGATCATCGGCCTCGGCGCAGT
CGAGCGCGCGGTGAAGGCGCGCCGCCACCGCCCGATCTTCATGGTCGACCTCGCGGTGCCGCGCGACATCGAGCCCGAAG
TCGGCAAGCTGAAGGACGTGTTCCTCTATACCGTCGACGATCTCGGCGCGATCGTGCGCGAAGGCAACGCATCGCGCCAG
GCCGCGGTCGCGCAGGCCGAAGCGATCATCGAAACGCGCGTGCAGAATTTCATGCAATGGCTCGACACGCGCAGCGTCGT
GCCGGTGATCCGTCACATGCATACGCAGGCCGACGCGCTGCGCCGCGCCGAAGTCGACAAGGCGCAGAAGCTGCTCGCGC
GCGGCGACGATCCGGCCGCCGTACTCGAAGCGCTGTCGCAGGCGCTGACCAACAAGCTGATCCACGGCCCGACGAGCGCG
CTCAACCGCGTGAACGGCGCCGATCGCGATTCGCTGATCGACCTGATGCGCGGCTTCTACCAGCACGCACCGCGCTCGAA
CGACCAGTCCGGCCACTAG

Upstream 100 bases:

>100_bases
AGCCCCCAAATTCGCGGCCCCGGCACGCTGATGCCCGGTATGCGGCGAGTGAGGAAATCGCTGAAACGCTATAATATGGG
GCTAAACGATAGCCCTCGAT

Downstream 100 bases:

>100_bases
CGCCGGCCGCTCGCCCTGCCGCCGGCCGCGTGCCGGCCTATCCTTTCCGAATACCCCTTGCCCGGGAGCGCCGCTCCACA
CCATGAAGACGAGCATGCAA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNTPEAAILSTCNRTELYCATDDRAAREGAVRWLSE
YHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRGT
TEIGTQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLAD
LPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRAEVDKAQKLLARGDDPAAVLEALSQALTNKLIHGPTSA
LNRVNGADRDSLIDLMRGFYQHAPRSNDQSGH

Sequences:

>Translated_432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNTPEAAILSTCNRTELYCATDDRAAREGAVRWLSE
YHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRGT
TEIGTQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLAD
LPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRAEVDKAQKLLARGDDPAAVLEALSQALTNKLIHGPTSA
LNRVNGADRDSLIDLMRGFYQHAPRSNDQSGH
>Mature_432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNTPEAAILSTCNRTELYCATDDRAAREGAVRWLSE
YHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRGT
TEIGTQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLAD
LPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRAEVDKAQKLLARGDDPAAVLEALSQALTNKLIHGPTSA
LNRVNGADRDSLIDLMRGFYQHAPRSNDQSGH

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=404, Percent_Identity=45.049504950495, Blast_Score=342, Evalue=4e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 47478; Mature: 47478

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNTPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCE
LYCATDDRAAREGAVRWLSEYHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCEECCCHHHHHHHHHHHHCCHHHHHHHH
QILGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRGTTEIGTQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHH
IFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLAD
HHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHCCCCCCHHH
LPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDV
CCHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHH
FLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADAL
HEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RRAEVDKAQKLLARGDDPAAVLEALSQALTNKLIHGPTSALNRVNGADRDSLIDLMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHH
QHAPRSNDQSGH
HHCCCCCCCCCC
>Mature Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNTPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCE
LYCATDDRAAREGAVRWLSEYHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCEECCCHHHHHHHHHHHHCCHHHHHHHH
QILGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRGTTEIGTQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHH
IFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLAD
HHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHCCCCCCHHH
LPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDV
CCHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHH
FLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADAL
HEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RRAEVDKAQKLLARGDDPAAVLEALSQALTNKLIHGPTSALNRVNGADRDSLIDLMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHH
QHAPRSNDQSGH
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA