Click here to switch to the map view.

The map label for this gene is mmlH [H]

Identifier: 78064982

GI number: 78064982

Start: 373100

End: 374362

Strand: Reverse

Name: mmlH [H]

Synonym: Bcep18194_A3505

Alternate gene names: 78064982

Gene position: 374362-373100 (Counterclockwise)

Preceding gene: 78064983

Following gene: 78064981

Centisome position: 10.13

GC content: 67.54

Gene sequence:

>1263_bases
ATGCAGGCATTCCAGTGGTTCAACGAACTGTCGACGCGCGAGCGCAGGACGCTGTACGCCGGCTTCGGCGGCTACGCGGT
CGATGCGTTCGACTTCATGATCTATTCGTTCCTGATTCCGACGCTGATCGCCACCTGGGGTATGACGAAGAGCGAGGCCG
GGATGATCGCGACGAGCTCGCTGATCTCGTCGGCGCTCGGCGGCTGGGTCGCCGGCATCCTCGCCGACCGCTACGGCCGC
GTGCGCGTGCTGCAGTGGACCATCGCGACGTTCGCGCTGTTCACGTGCCTGTCCGGTTTCACCCACTCGTTCTGGCAGTT
GCTCGCGACGCGTACGCTGCAGGGCTTCGGCTTCGGCGGCGAATGGTCGGTCGTGACGATCATGATGGCCGAGACGATCC
GCTCGCCCGAGCATCGCGGGAAGGCGGTCGGCACCGTGCAGAGCAGCTGGTCGTTCGGCTGGGGCGCGGCCGCGATCCTC
TACTGGGCGTTCTTCGCACTGCTGCCCGAGCAGGTCGCCTGGCGCGCGTGCTTCTGGATCGGCATCCTGCCCGCGCTGTG
GATCCTGTACATCCGCCGCAACGTCAGCGATCCCGACGTCTATACGGCCACCCGCCGCGCGCGCGACGAAGGCCGCGTGT
CAGGCCACTTCCTCGAGATCTTCTCGCCGCCGCACCTGCGCGCGACGCTGTTCGGCAGCGCGCTGTGCACCGGCATGCTC
GGCGGCTACTACGCGATCACGACGTGGCTGCCCACCTACCTGAAAACCGTCCGCCACCTGTCGGTGTTCAACACGAGCGG
CTATCTCGTCGTGTTGATCGTCGGCTCGTTCGTCGGCTATGTGGTCGGCGCGATCCTGTCCGACCGGCTCGGCCGCCGCG
CGTCGTTCATCCTGTTCGCGATCGGCTCGTTCTCGCTCGGCATGGCGTACACGATGCTGCCGATCACCGATACCGCGATG
CTGCTGCTCGGCTTCCCGCTCGGCATCGTCGTGCAGGGGATCTTCGCGGGCGTCGGCGCGTACCTGTCGGAGCTGTATCC
GGGCGCGATCCGCGGGTCGGGCCAGGGCTTCTGCTACAACCTCGGGCGCGGGCTCGGCTCGTTCTTCCCGATCCTCGTCG
GCTCGCTGTCGCAGTCGATGTCGCTCGTGAAGGCGATCGGCCTCGTCGCGGGCGGCGGCTACCTGCTCGTGATCGTCGCC
GCGCTCGTGCTGCCGGAAACGCGCGGCAAGTCGCTCGTCGACGATCCGGCCGTCGCGTCGTGA

Upstream 100 bases:

>100_bases
GCCGCGCACCTGCACTCACCTTTTTGGCACCCCGCATCCCGCCCGTAAAATAGCCGCCAGACGGCAAGCGCGAGACGGGA
CAAAAGAGGGGGCGGCAAGC

Downstream 100 bases:

>100_bases
GCCACCGCTTCGTTCCGGAAACCGCATGCACGTGATCGTTCTCGGCGCCGGCGTGATCGGCGTCGCCACCGCCTGGCACC
TGCGCGAAGCAGGCTGCGAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSALGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRGKAVGTVQSSWSFGWGAAAIL
YWAFFALLPEQVAWRACFWIGILPALWILYIRRNVSDPDVYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAIGSFSLGMAYTMLPITDTAM
LLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGSLSQSMSLVKAIGLVAGGGYLLVIVA
ALVLPETRGKSLVDDPAVAS

Sequences:

>Translated_420_residues
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSALGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRGKAVGTVQSSWSFGWGAAAIL
YWAFFALLPEQVAWRACFWIGILPALWILYIRRNVSDPDVYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAIGSFSLGMAYTMLPITDTAM
LLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGSLSQSMSLVKAIGLVAGGGYLLVIVA
ALVLPETRGKSLVDDPAVAS
>Mature_420_residues
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSALGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRGKAVGTVQSSWSFGWGAAAIL
YWAFFALLPEQVAWRACFWIGILPALWILYIRRNVSDPDVYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAIGSFSLGMAYTMLPITDTAM
LLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGSLSQSMSLVKAIGLVAGGGYLLVIVA
ALVLPETRGKSLVDDPAVAS

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=378, Percent_Identity=27.5132275132275, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87082231, Length=442, Percent_Identity=24.8868778280543, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790550, Length=438, Percent_Identity=25.5707762557078, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082159, Length=365, Percent_Identity=27.9452054794521, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081723, Length=337, Percent_Identity=26.1127596439169, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789152, Length=380, Percent_Identity=24.4736842105263, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=445, Percent_Identity=24.4943820224719, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45610; Mature: 45610

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSS
CCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LISSALGGWVAGILADRYGRVRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EWSVVTIMMAETIRSPEHRGKAVGTVQSSWSFGWGAAAILYWAFFALLPEQVAWRACFWI
CHHHHHHHHHHHHCCHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILPALWILYIRRNVSDPDVYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHEEE
IGSFSLGMAYTMLPITDTAMLLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYN
CCCHHHHHHHEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGRGLGSFFPILVGSLSQSMSLVKAIGLVAGGGYLLVIVAALVLPETRGKSLVDDPAVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQAFQWFNELSTRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSS
CCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LISSALGGWVAGILADRYGRVRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EWSVVTIMMAETIRSPEHRGKAVGTVQSSWSFGWGAAAILYWAFFALLPEQVAWRACFWI
CHHHHHHHHHHHHCCHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILPALWILYIRRNVSDPDVYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHEEE
IGSFSLGMAYTMLPITDTAMLLLGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYN
CCCHHHHHHHEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGRGLGSFFPILVGSLSQSMSLVKAIGLVAGGGYLLVIVAALVLPETRGKSLVDDPAVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]