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The map label for this gene is aroB

Identifier: 78064967

GI number: 78064967

Start: 353341

End: 354420

Strand: Direct

Name: aroB

Synonym: Bcep18194_A3490

Alternate gene names: 78064967

Gene position: 353341-354420 (Clockwise)

Preceding gene: 78064966

Following gene: 78064968

Centisome position: 9.56

GC content: 67.78

Gene sequence:

>1080_bases
ATGATTACTGTCAACGTCGATCTGGGCGACCGCGCCTATCCGATTCACATTGGCGCCGGCCTGATCGGCCGCGCCGAGTT
GTTCGCGCCTCACATCAAGGGCTCGTCCGTCACGATCGTCACGAACACGACGGTCGATCCGCTTTACGGCGACGCGCTGC
GCGCGGCGCTCGCGCCGCTCGGCAAGCGCGTGTCGACGGTCGTGCTGCCGGACGGCGAGGCGTACAAGAACTGGGAAACG
CTGAACCTGATCTTCGACGGCCTGCTGACCGACCGCGCGGACCGCAAGACGACGCTCGTCGCACTCGGCGGCGGCGTGGT
CGGCGACATGACGGGCTTTGCGGCCGCGTGCTACATGCGCGGCGTGCCGTTCATCCAGGTGCCGACGACGCTGCTGTCGC
AGGTCGACTCGTCGGTCGGCGGCAAGACGGGCATCAACCACCCGCTCGGCAAGAACATGATCGGCGCGTTCTACCAGCCG
CAGGCCGTAATCGCGGACATCGGTGCGCTCACGACCCTGCCCGACCGCGAACTGGCGGCCGGTGTTGCCGAGATCATCAA
GACCGGCGCAATTGCCGATGCGGAATTCTTCGACTGGATCGAGGCGAACGTCGACGCGCTGAACCGTCGCGACCCGGCTG
CGCTCGCGCACGCTGTGAAGCGCTCGTGCGAGATCAAGGCGAGCGTGGTGGCGGCCGACGAACGCGAAGGCGGCCTGCGC
GCGATCCTGAACTTCGGCCACACGTTCGGCCATGCGATCGAGGCCGGGCTCGGCTACGGCGAGTGGCTGCACGGCGAAGC
GGTCGGCTGCGGAATGGTGATGGCGGGCGACCTGTCGGTGCGGCTCGGCCTGCTCGACGAAGCGTCGCGGCAGCGCCTCG
ATGCGGTGATCGCGGCCGCGCACCTGCCGACCCGCGGGCCTGCACTCGGCGACGCGCGCTACCTGGACCTGATGCGCGTC
GACAAGAAGGCGGAAGCCGGCGCGATCAAGTTCATCCTGCTGAAGCGATTCGGCGATACGCTGATCACGCAGGCGCCGGA
CGAAGCCGTGTTCGCTACACTGGCGCAGACGACCCACTAA

Upstream 100 bases:

>100_bases
ATTTCGTCATCGAGACCGGCCGTCCGTCGGTCAACGGTCTCGTCAACATGGTGCTGATGCAACTCGAACTGGCCGGCGTC
ATCGCCAAGCCGCTACAAGC

Downstream 100 bases:

>100_bases
CGGCCGCCCGGATGCCCCGGCGCCCCTGACATGGAGGAGACGTGAGCGAGACATCCAGCAGCACACTGCCCGAAGCCGGC
CGCGCATCCGCTGCGCCGGT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLTDRADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPDRELAAGVAEIIKTGAIADAEFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAAHLPTRGPALGDARYLDLMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTH

Sequences:

>Translated_359_residues
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLTDRADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPDRELAAGVAEIIKTGAIADAEFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAAHLPTRGPALGDARYLDLMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTH
>Mature_359_residues
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLTDRADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPDRELAAGVAEIIKTGAIADAEFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAAHLPTRGPALGDARYLDLMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=334, Percent_Identity=58.3832335329341, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6320332, Length=368, Percent_Identity=39.1304347826087, Blast_Score=223, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 37875; Mature: 37875

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPL
CEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GKRVSTVVLPDGEAYKNWETLNLIFDGLLTDRADRKTTLVALGGGVVGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALTTLPDRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
GVAEIIKTGAIADAEFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
HHHHHHHHCCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAA
HHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHH
HLPTRGPALGDARYLDLMRVDKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTH
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPL
CEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GKRVSTVVLPDGEAYKNWETLNLIFDGLLTDRADRKTTLVALGGGVVGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALTTLPDRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
GVAEIIKTGAIADAEFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
HHHHHHHHCCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAA
HHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHH
HLPTRGPALGDARYLDLMRVDKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTH
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA