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The map label for this gene is ttuB [H]

Identifier: 78050029

GI number: 78050029

Start: 5159252

End: 5160562

Strand: Reverse

Name: ttuB [H]

Synonym: XCV4473

Alternate gene names: 78050029

Gene position: 5160562-5159252 (Counterclockwise)

Preceding gene: 78050030

Following gene: 78050028

Centisome position: 99.65

GC content: 68.04

Gene sequence:

>1311_bases
ATGACCCAAGCCACCCGGCCCCTGCCGCCCTCCGATGACATGGGTCCGACCTACCGCAAGATCCTGTGGCGGCTGATCCC
GTTCCTGTTCGTCTGCTACCTGTTCAATTACCTGGACCGGGTCAACGTGGGCTTTGCCAAGCTGCAGATGCTGGGCGACC
TGGGCATGAGCGAGACCGTGTACGGGCTGGGCGCGGGCATTTTCTTCATCGGTTACCTGGCCTGCGGGGTGCCGAGCAAT
CTGATCCTGCAGCGCATCGGTGCCCGGCGCTGGGTGGCGATCATGATGGTCAGCTGGGGCCTGCTCTCCACCTGCCTGCT
GTTCGTGCGCACCCCGGCCGGGTTCTACACCCTGCGCCTGCTCACCGGTGCGGCCGAGGCGGGCTTCTTTCCCGGCATCG
TGCTGTACCTGACCCGCTGGTTCCCGCGTGCCCGGCATGGCCGGGTCATGACCGTGTTCATGTCGGCGATCCCGATCTCC
GGGGTGCTGGGCGGGCCGTTGTCCGGCTGGATCCTGGATCACTTCTCGGCCGGGCAGGGCGGCCTGGCCGGCTGGCAATG
GATGTTCCTGCTGCAGGGCCTGCCGACCGTGTTGCTGGGCATCGGGGTGTGGTTCCTGCTCAGCGACGGCGTGCAACAGG
CCAGCTGGCTCAACCCGCAGGAAAAACAGGCCTTGGCACGCGTGCTGGCCGAGGACGAAGCAGGCAAGCCAGCCGGCGCG
TCCACCTCGCTGGGCGCGGTGCTGCGCAATCCGGCGGTGTGGCTGCTGGGCACGGTGTACTTCTGCATCCAGAGCGGGGT
GTATGCGATCAACTTCTGGCTGCCGTCGATCATCCAGGGCAGCGGTGTCACCGACCCGATCCGCATCGGTCTGATGAGCG
CGATCCCGTACCTGGCCGCGGCGGTGTTCATGGTGCTGATGGGCCGTTCGGCCGACCGTCGCGGCGAGCGTCGCTGGCAC
TTGGTGATTCCGTTGCTGATGGGCGCGGCCGGCCTGTGCATCGCCGCCAGCGTCACCGACAACCTGGGCCTGGCGGTGTT
CGGCATGACCCTGGCCACGATGGGGGCGGTCAGCGGCTTGCCGCTGTTTTGGCCGCTGACCAACGGCTTTCTCACCGCCG
CCGCCGCCGCCGGTGGGCTGGCGCTGATCAATTCCACCGGCCAGGTGGCCGGTTTCCTCAGCCCGTATCTGGTGGGCTGG
ATCAAGGACACCACCCACAGCACCGAAGTGGCGCTGTACGTGCTGGCCGGCGCCATGGCGCTGGGCGCCGCGCTGGTGCT
GCGGGTGCCGGCGCGGGCGGTGAACCGGTGA

Upstream 100 bases:

>100_bases
ATTCCGGGAAAACGCTCAATCTAGAATGCGTCGACCACCTGCCTGGTGTCGGTGCTGCCGCACTGCGCACCGGCTGGCCT
TCCGACTGCTGGAGCGTGCG

Downstream 100 bases:

>100_bases
TGCGTCCGTCCCAGCGAGTGTCCGCATGAAGATCGTCATTGCCCCCGATTCGTACAAGGAAAGCCTGCCCGCGCTGGAGG
TGGCCACGCAGATCGAGGCG

Product: anion:cation symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTQATRPLPPSDDMGPTYRKILWRLIPFLFVCYLFNYLDRVNVGFAKLQMLGDLGMSETVYGLGAGIFFIGYLACGVPSN
LILQRIGARRWVAIMMVSWGLLSTCLLFVRTPAGFYTLRLLTGAAEAGFFPGIVLYLTRWFPRARHGRVMTVFMSAIPIS
GVLGGPLSGWILDHFSAGQGGLAGWQWMFLLQGLPTVLLGIGVWFLLSDGVQQASWLNPQEKQALARVLAEDEAGKPAGA
STSLGAVLRNPAVWLLGTVYFCIQSGVYAINFWLPSIIQGSGVTDPIRIGLMSAIPYLAAAVFMVLMGRSADRRGERRWH
LVIPLLMGAAGLCIAASVTDNLGLAVFGMTLATMGAVSGLPLFWPLTNGFLTAAAAAGGLALINSTGQVAGFLSPYLVGW
IKDTTHSTEVALYVLAGAMALGAALVLRVPARAVNR

Sequences:

>Translated_436_residues
MTQATRPLPPSDDMGPTYRKILWRLIPFLFVCYLFNYLDRVNVGFAKLQMLGDLGMSETVYGLGAGIFFIGYLACGVPSN
LILQRIGARRWVAIMMVSWGLLSTCLLFVRTPAGFYTLRLLTGAAEAGFFPGIVLYLTRWFPRARHGRVMTVFMSAIPIS
GVLGGPLSGWILDHFSAGQGGLAGWQWMFLLQGLPTVLLGIGVWFLLSDGVQQASWLNPQEKQALARVLAEDEAGKPAGA
STSLGAVLRNPAVWLLGTVYFCIQSGVYAINFWLPSIIQGSGVTDPIRIGLMSAIPYLAAAVFMVLMGRSADRRGERRWH
LVIPLLMGAAGLCIAASVTDNLGLAVFGMTLATMGAVSGLPLFWPLTNGFLTAAAAAGGLALINSTGQVAGFLSPYLVGW
IKDTTHSTEVALYVLAGAMALGAALVLRVPARAVNR
>Mature_435_residues
TQATRPLPPSDDMGPTYRKILWRLIPFLFVCYLFNYLDRVNVGFAKLQMLGDLGMSETVYGLGAGIFFIGYLACGVPSNL
ILQRIGARRWVAIMMVSWGLLSTCLLFVRTPAGFYTLRLLTGAAEAGFFPGIVLYLTRWFPRARHGRVMTVFMSAIPISG
VLGGPLSGWILDHFSAGQGGLAGWQWMFLLQGLPTVLLGIGVWFLLSDGVQQASWLNPQEKQALARVLAEDEAGKPAGAS
TSLGAVLRNPAVWLLGTVYFCIQSGVYAINFWLPSIIQGSGVTDPIRIGLMSAIPYLAAAVFMVLMGRSADRRGERRWHL
VIPLLMGAAGLCIAASVTDNLGLAVFGMTLATMGAVSGLPLFWPLTNGFLTAAAAAGGLALINSTGQVAGFLSPYLVGWI
KDTTHSTEVALYVLAGAMALGAALVLRVPARAVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=309, Percent_Identity=23.9482200647249, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=36.2768496420048, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI2367379, Length=447, Percent_Identity=25.7270693512304, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789152, Length=442, Percent_Identity=24.6606334841629, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789515, Length=419, Percent_Identity=25.5369928400955, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082320, Length=375, Percent_Identity=25.0666666666667, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17552542, Length=395, Percent_Identity=25.0632911392405, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=233, Percent_Identity=26.1802575107296, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321698, Length=347, Percent_Identity=23.342939481268, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=234, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=148, Percent_Identity=25, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=238, Percent_Identity=21.8487394957983, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323032, Length=227, Percent_Identity=23.7885462555066, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24584153, Length=377, Percent_Identity=24.1379310344828, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583789, Length=371, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46720; Mature: 46589

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHCC
>Mature Secondary Structure 
TQATRPLPPSDDMGPTYRKILWRLIPFLFVCYLFNYLDRVNVGFAKLQMLGDLGMSETV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHH
YGLGAGIFFIGYLACGVPSNLILQRIGARRWVAIMMVSWGLLSTCLLFVRTPAGFYTLRL
HHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LTGAAEAGFFPGIVLYLTRWFPRARHGRVMTVFMSAIPISGVLGGPLSGWILDHFSAGQG
HHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCC
GLAGWQWMFLLQGLPTVLLGIGVWFLLSDGVQQASWLNPQEKQALARVLAEDEAGKPAGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
STSLGAVLRNPAVWLLGTVYFCIQSGVYAINFWLPSIIQGSGVTDPIRIGLMSAIPYLAA
CHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AVFMVLMGRSADRRGERRWHLVIPLLMGAAGLCIAASVTDNLGLAVFGMTLATMGAVSGL
HHHHHHHCCCCCCCCCCEEEEHHHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHCCC
PLFWPLTNGFLTAAAAAGGLALINSTGQVAGFLSPYLVGWIKDTTHSTEVALYVLAGAMA
CEEEEHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LGAALVLRVPARAVNR
HHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]