Click here to switch to the map view.

The map label for this gene is yeaD [H]

Identifier: 78049951

GI number: 78049951

Start: 5066432

End: 5068594

Strand: Reverse

Name: yeaD [H]

Synonym: XCV4395

Alternate gene names: 78049951

Gene position: 5068594-5066432 (Counterclockwise)

Preceding gene: 78049952

Following gene: 78049950

Centisome position: 97.88

GC content: 70.6

Gene sequence:

>2163_bases
ATGACGCTGGCCCGGCGTGCATTGCCGTTCGTGTTGGGACTGCTGCCGCTGGCAGCCTCTGCCGATCCGGCCTTCGACCG
CTGCCTGGCTGGCCTGCAGCCCCAGGCCGCTGCCAAGGGCGTGGACGCTGCCAGCTTTCAGCGCTTCACCGCCGGGCTGG
CGCCCGATCCCAGCGTGCTGCCGCTGCTGGATGCGCAGCCCGAATTCACCACGCCCATCTGGGATTACCTGGCCAGCCTG
GTCGACAGCCAGCGTGTCAGCGACGGCCAGGCCATGCTGGTTACCCACCGCGAACTGCTTGCCCGCCTGTCCGAACAGAC
CGGCGTGGACCCGGCCACCATCGTGGCGGTGTGGGGCGTGGAGAGCGATTACGGCCGCGTCACCGGCAAGCGCCCGCTGC
TGGTGTCGCTGGCCACGCTGTCGTGCGCGGGCCGCCGCCAGCCGTTCTTTCGCGGCGAATTCCTCGCCTTGCTCAGCCTG
CTGCAGCAAGGCGATCTGTCGGCGGAAGGACTCACCGGCTCCTGGGCCGGTGCGTTCGGGCAAACCCAGTTCATGCCTTC
GACCTACGCCCGCATCGCCGTGGATGGCGACGGCGACGGCCGCCGCGATCTGGTGACCAGCATTCCCGATGCACTGGCCT
CCACCGCCAACTACCTGGTCAAGGCCGGCTGGGAACGCGCCCGTCCGTGGGGCATGGAAGTCACCCTGCCGCGGGGCTTC
GACGCCAGCAAGGCCGGGCGCACCCGCCGCCAACCGCTGCAGGCCTGGCAACGCGCCGGCCTGCTCGGCACCGACGGCAC
ACCGCTGGCACCGGCCGGACTGCCGGCAGAAACGCCGGCCGCCTTGCTGTTGCCGGCCGGTGCCAGCGGCCCGGCGTTCC
TGGTGTTTGGCAACTACGACGCGATCTACGCCTACAACGCCGCCGAAAGTTACGCGCTGTCCATCGCCCTGCTCGCCGAT
CGCCTGCGTGGCGGCCCCGGCCTGATCGCGGCCTGGCCCACGGACGATCCGGGCCTGGGCCGGCCCGAACGGCGCGAACT
GCAGCAGTTGCTGCTCGCCCGTGGCTACCAGATCGGCGAGGCCGACGGCATGGTCGGCAGCGCCACCCGCCGCGCCATCC
AGGTCGAGCAGACCCGCCTGGGCCTGCAACCGGCCGACGGCCGCCCCGGCCAACGCATCCTCACCGCGCTGCGCGCCGCC
CCGCCAGTTACCGGCGCCGCCGCCATGCGCGCCACCGCGTTCAAGCTGCCGGCCGCATACCCGGCCTTCGCCCAATCCCC
CAGCGTCCACAAGGCATCCCCCATGTCCGACACCACCGGCCTGACCACAGGCGATTTCCACGGGTTTCCGTCGCTGCTGA
TCGACACCCCGTTCTCCACCGCCGCCATCAGCCTGTTCGGCGGTCAATTGCTCTCGTTCGTGCCCAAGGGCGGACAGGAC
GTGATGTGGCTCTCGCCCAGTGCCAAGCAGCCGCCTACCCCGATCCGCGGCGGCGCGCCGGTGTGCTGGCCGTATTTCGG
CCGCCAGGACCAGACCGGCGACGTCCCCGCCCACGGCTTCGTGCGCACGGTGGCCTGGCAACTCACCGAAAGCCGCCGTG
AAGACGACGGCACCGTGGTGCTCACGCTCACCCCGCCGCGTTTCGACGACCTGGCGCTGCGCCTGCGCATGACCCTGCGC
ATCGGCCGCACGCTGGAGCAACGCCTGATCACCGAAAACACCAGCGCCGCCCCGGTGCGTTTCACCCAGGCGCTGCACAA
CTATTTCCGTGTCGGCGACGCGCTCAAGGTCAGCGTGCAGGGCCTGGATGGCCTGGACTATCTCGATAAGTACGAGAACT
ACGCCACTGCCCATCGCCAGCAAGGCGACTGGAGCCTGCGCGACCCACGCGACCCCGGCCGCAGCGACCGCATCTACACC
AATGCCGGCGGCCGCTACACGCTCACCGACCCGGTGCTCGGCCGCCGCGTCGTCATCGCTACCGAAGGCAGCCGCTCGCT
GGTGGCCTGGAACCCGGGCGAAGAGGCCGGCAGGCAGATGGCCGACGTGGGCGAGGGCTGGCGCGACTACGTCTGCCTGG
AAGCGGCCAATGCCGGCCCGGACGTGATCGAACTCGCTCCCGGCGCCAGCCACACCCTGACCCAGACCATCAGCGTCGAG
TAG

Upstream 100 bases:

>100_bases
GCACGCTTGTGACCCCCAGGTTGGCTATGCTCGGCGGCTAGACTTGCCGCGCAGGAGCACTTCACCGCATGACGTCTGTC
CACCCGCCAGCCATCGCGCC

Downstream 100 bases:

>100_bases
CCGCCCAGGCCCGCGCTGCTGTCTACGCCAAAAATAAAGCAGCATCGAGGCTTCCTTCTCCCATCGGAAGAAGGTGCCCG
AAGGGCGGATGAGGGTACGC

Product: putative transglycosylase precursor

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MTLARRALPFVLGLLPLAASADPAFDRCLAGLQPQAAAKGVDAASFQRFTAGLAPDPSVLPLLDAQPEFTTPIWDYLASL
VDSQRVSDGQAMLVTHRELLARLSEQTGVDPATIVAVWGVESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSL
LQQGDLSAEGLTGSWAGAFGQTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
DASKAGRTRRQPLQAWQRAGLLGTDGTPLAPAGLPAETPAALLLPAGASGPAFLVFGNYDAIYAYNAAESYALSIALLAD
RLRGGPGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGEADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILTALRAA
PPVTGAAAMRATAFKLPAAYPAFAQSPSVHKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPKGGQD
VMWLSPSAKQPPTPIRGGAPVCWPYFGRQDQTGDVPAHGFVRTVAWQLTESRREDDGTVVLTLTPPRFDDLALRLRMTLR
IGRTLEQRLITENTSAAPVRFTQALHNYFRVGDALKVSVQGLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYT
NAGGRYTLTDPVLGRRVVIATEGSRSLVAWNPGEEAGRQMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE

Sequences:

>Translated_720_residues
MTLARRALPFVLGLLPLAASADPAFDRCLAGLQPQAAAKGVDAASFQRFTAGLAPDPSVLPLLDAQPEFTTPIWDYLASL
VDSQRVSDGQAMLVTHRELLARLSEQTGVDPATIVAVWGVESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSL
LQQGDLSAEGLTGSWAGAFGQTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
DASKAGRTRRQPLQAWQRAGLLGTDGTPLAPAGLPAETPAALLLPAGASGPAFLVFGNYDAIYAYNAAESYALSIALLAD
RLRGGPGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGEADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILTALRAA
PPVTGAAAMRATAFKLPAAYPAFAQSPSVHKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPKGGQD
VMWLSPSAKQPPTPIRGGAPVCWPYFGRQDQTGDVPAHGFVRTVAWQLTESRREDDGTVVLTLTPPRFDDLALRLRMTLR
IGRTLEQRLITENTSAAPVRFTQALHNYFRVGDALKVSVQGLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYT
NAGGRYTLTDPVLGRRVVIATEGSRSLVAWNPGEEAGRQMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE
>Mature_719_residues
TLARRALPFVLGLLPLAASADPAFDRCLAGLQPQAAAKGVDAASFQRFTAGLAPDPSVLPLLDAQPEFTTPIWDYLASLV
DSQRVSDGQAMLVTHRELLARLSEQTGVDPATIVAVWGVESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSLL
QQGDLSAEGLTGSWAGAFGQTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGFD
ASKAGRTRRQPLQAWQRAGLLGTDGTPLAPAGLPAETPAALLLPAGASGPAFLVFGNYDAIYAYNAAESYALSIALLADR
LRGGPGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGEADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILTALRAAP
PVTGAAAMRATAFKLPAAYPAFAQSPSVHKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPKGGQDV
MWLSPSAKQPPTPIRGGAPVCWPYFGRQDQTGDVPAHGFVRTVAWQLTESRREDDGTVVLTLTPPRFDDLALRLRMTLRI
GRTLEQRLITENTSAAPVRFTQALHNYFRVGDALKVSVQGLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYTN
AGGRYTLTDPVLGRRVVIATEGSRSLVAWNPGEEAGRQMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE

Specific function: Unknown

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=280, Percent_Identity=33.9285714285714, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1789053, Length=249, Percent_Identity=33.7349397590361, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323746, Length=287, Percent_Identity=27.1777003484321, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19921284, Length=271, Percent_Identity=24.7232472324723, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 77105; Mature: 76974

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLARRALPFVLGLLPLAASADPAFDRCLAGLQPQAAAKGVDAASFQRFTAGLAPDPSVL
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHCCCCCCCCEE
PLLDAQPEFTTPIWDYLASLVDSQRVSDGQAMLVTHRELLARLSEQTGVDPATIVAVWGV
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEECC
ESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSLLQQGDLSAEGLTGSWAGAFG
CCCCCCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
QTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCC
DASKAGRTRRQPLQAWQRAGLLGTDGTPLAPAGLPAETPAALLLPAGASGPAFLVFGNYD
CCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCC
AIYAYNAAESYALSIALLADRLRGGPGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGE
EEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCC
ADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILTALRAAPPVTGAAAMRATAFKLPAAY
CCCCCCHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
PAFAQSPSVHKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPKGGQD
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHCCCCCCE
VMWLSPSAKQPPTPIRGGAPVCWPYFGRQDQTGDVPAHGFVRTVAWQLTESRREDDGTVV
EEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
LTLTPPRFDDLALRLRMTLRIGRTLEQRLITENTSAAPVRFTQALHNYFRVGDALKVSVQ
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEE
GLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYTNAGGRYTLTDPVLGRRVVIA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEE
TEGSRSLVAWNPGEEAGRQMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE
ECCCCEEEEECCCHHHHHHHHHHCCCCHHEEEEEECCCCCCEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
TLARRALPFVLGLLPLAASADPAFDRCLAGLQPQAAAKGVDAASFQRFTAGLAPDPSVL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHCCCCCCCCEE
PLLDAQPEFTTPIWDYLASLVDSQRVSDGQAMLVTHRELLARLSEQTGVDPATIVAVWGV
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEECC
ESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSLLQQGDLSAEGLTGSWAGAFG
CCCCCCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
QTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCC
DASKAGRTRRQPLQAWQRAGLLGTDGTPLAPAGLPAETPAALLLPAGASGPAFLVFGNYD
CCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCC
AIYAYNAAESYALSIALLADRLRGGPGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGE
EEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCC
ADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILTALRAAPPVTGAAAMRATAFKLPAAY
CCCCCCHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
PAFAQSPSVHKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPKGGQD
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHCCCCCCE
VMWLSPSAKQPPTPIRGGAPVCWPYFGRQDQTGDVPAHGFVRTVAWQLTESRREDDGTVV
EEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
LTLTPPRFDDLALRLRMTLRIGRTLEQRLITENTSAAPVRFTQALHNYFRVGDALKVSVQ
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEE
GLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYTNAGGRYTLTDPVLGRRVVIA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEE
TEGSRSLVAWNPGEEAGRQMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE
ECCCCEEEEECCCHHHHHHHHHHCCCCHHEEEEEECCCCCCEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]