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The map label for this gene is bioC [C]

Identifier: 78049774

GI number: 78049774

Start: 4843315

End: 4844646

Strand: Reverse

Name: bioC [C]

Synonym: XCV4218

Alternate gene names: 78049774

Gene position: 4844646-4843315 (Counterclockwise)

Preceding gene: 78049775

Following gene: 78049773

Centisome position: 93.55

GC content: 68.84

Gene sequence:

>1332_bases
ATGCAAACTGCGCCACAGCCACTTACCGAGCCACTGCAGCAGGCGATCGCCGCGCACCGCAGTGGCCAACTCGAACATGC
CGCGCAGCTGTACACGCAGCTGCTGGACGATCAGCCCGCGCACGCCGACGCGCTGCATTACCAGGGCATCCTGTTGCATC
AGCGCGGCAACAGCGCCGCGGCGGTGGCCTCCATCACCCAGGCGTTGACGCTGGCGCCCGCGCAACCGGATGCCTGCAAC
AACCTGGGCAACGTGCACCGCGAATGCGGCCGCCTGCGCGATGCCGAACACTGCTATCGCCGCGCACTGGCGCTGGCGCC
TGCACATGCCGACGCGCTGGCGAATCTGGCAGCGGTGCTGGAAGCGCAGCGGCGCAGCGAAGAAGCCTTCGTCACCTACG
CGGCGCTGTTGCACACCTATCCGCAGTCCGCGCATGCGCATTACCTGCTCGGCCTGTTCCTGCGCAACAACGCGCAGGCC
GCCGAGCATCTGCAGCAATCGGTGCAGTGCCTGCAGCAGGCCTGCACGCTGGCACCGGACCACCTGCACGCCCGCGAGGC
GCTGGGCACCGGGCTCTACCTGTTGGGCGAGCATGCGCAGGCGCAAACGGTGTATCGCGACTGGCTCACGCTTGAGCCGG
GCAACCCGGTGGCAACGCATATGCTGGCGGCCTGTGGCGGCGCCGAACCGCCGCCGCGTGCCGGCGATACCTATGTGCGT
GAACTGTTCGATGGCTTTGCCGACAGTTTCGACGAACAGTTGCTGCATCACCTGGAGTACCGCGCGCCGCAACGGCTGAC
CAAGGCACTGGCGGCCTGCCTTGCGCCACCGCATGCGGGCCTGCGCATGCTCGATGCCGGCTGCGGCACCGGGCTGTGTG
CGCCGCTGTGGCGCCCGTATGCACATCAACTGGTGGGCGTGGACCTGTCGCCTGGCATGGTCGCCAAGGCACGCCAACGC
GGTGGCTACGATCGGCTGGAGGTCGCCGAACTCACCGCATACCTGCACGCGCAGCACGCGCAGTGGGATGTGATCGGCTC
GGCCGACACCTTGGTGTACTTCGGCGCGCTGCAGCCGGTGCTCGCTGCCGCTGCCGGCGCGCTCACGCCAGGGGGCGTGC
TGGGTTTCACGGTCGAAGCGCTGGACGAGCCGGACGACCGGGTCGAACTCGATGCCAGCGGGCGCTATCGGCACAGCCAT
GCGCACGTGCGCGCCGCATTGCAAGGCGCCGGTTTGCAGCCGATCGCGTTGGAACTGGACGTGCTGCGCAGCGAACGTGG
CCAGCCGGTGCACGGCTGGGTCGTGACCGCGCGCACGCCTGGGCCAGCCTGA

Upstream 100 bases:

>100_bases
ACGGTCGTGCTGTTGGCGGCTCGTTGCAGACATGACGCCCTGCCATTCCGCGCTCACATTCGTACCCGCACCACCGGTTG
CCGTGTCCTTGGAGAAGCTC

Downstream 100 bases:

>100_bases
GACGAAATGTCGGCTTTGCTGCACGCACGCATGTGAGCATGCGCGTGACAGTTGCCGTGCCTTTAGCCGCCTGACGTTGC
ACGCGCGGGCGCAACGCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: TPR Repeat-Containing Protein; Methyltransferase; 3-Demethylubiquinone-9 3-Methyltransferase; Methyltransferase Protein; Tetratricopeptide TPR_2 Repeat Protein; SAM-Dependent Methyltransferase; Peptidase S1 And S6 Chymotrypsin/Hap; SAM-Dependent Methyltransferases; Tetratricopeptide Repeat-Containing Protein; Protein With TPR Motifs; TPR Repeat-Containing Methyltransferase; Two Domain Fusion Protein; Methyltransferase Domain Family; Methyltransferase Domain Family Protein; TPR Domain-Containing Protein

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQTAPQPLTEPLQQAIAAHRSGQLEHAAQLYTQLLDDQPAHADALHYQGILLHQRGNSAAAVASITQALTLAPAQPDACN
NLGNVHRECGRLRDAEHCYRRALALAPAHADALANLAAVLEAQRRSEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQA
AEHLQQSVQCLQQACTLAPDHLHAREALGTGLYLLGEHAQAQTVYRDWLTLEPGNPVATHMLAACGGAEPPPRAGDTYVR
ELFDGFADSFDEQLLHHLEYRAPQRLTKALAACLAPPHAGLRMLDAGCGTGLCAPLWRPYAHQLVGVDLSPGMVAKARQR
GGYDRLEVAELTAYLHAQHAQWDVIGSADTLVYFGALQPVLAAAAGALTPGGVLGFTVEALDEPDDRVELDASGRYRHSH
AHVRAALQGAGLQPIALELDVLRSERGQPVHGWVVTARTPGPA

Sequences:

>Translated_443_residues
MQTAPQPLTEPLQQAIAAHRSGQLEHAAQLYTQLLDDQPAHADALHYQGILLHQRGNSAAAVASITQALTLAPAQPDACN
NLGNVHRECGRLRDAEHCYRRALALAPAHADALANLAAVLEAQRRSEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQA
AEHLQQSVQCLQQACTLAPDHLHAREALGTGLYLLGEHAQAQTVYRDWLTLEPGNPVATHMLAACGGAEPPPRAGDTYVR
ELFDGFADSFDEQLLHHLEYRAPQRLTKALAACLAPPHAGLRMLDAGCGTGLCAPLWRPYAHQLVGVDLSPGMVAKARQR
GGYDRLEVAELTAYLHAQHAQWDVIGSADTLVYFGALQPVLAAAAGALTPGGVLGFTVEALDEPDDRVELDASGRYRHSH
AHVRAALQGAGLQPIALELDVLRSERGQPVHGWVVTARTPGPA
>Mature_443_residues
MQTAPQPLTEPLQQAIAAHRSGQLEHAAQLYTQLLDDQPAHADALHYQGILLHQRGNSAAAVASITQALTLAPAQPDACN
NLGNVHRECGRLRDAEHCYRRALALAPAHADALANLAAVLEAQRRSEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQA
AEHLQQSVQCLQQACTLAPDHLHAREALGTGLYLLGEHAQAQTVYRDWLTLEPGNPVATHMLAACGGAEPPPRAGDTYVR
ELFDGFADSFDEQLLHHLEYRAPQRLTKALAACLAPPHAGLRMLDAGCGTGLCAPLWRPYAHQLVGVDLSPGMVAKARQR
GGYDRLEVAELTAYLHAQHAQWDVIGSADTLVYFGALQPVLAAAAGALTPGGVLGFTVEALDEPDDRVELDASGRYRHSH
AHVRAALQGAGLQPIALELDVLRSERGQPVHGWVVTARTPGPA

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG4976

COG function: function code R; Predicted methyltransferase (contains TPR repeat)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307148, Length=263, Percent_Identity=28.5171102661597, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI32307150, Length=263, Percent_Identity=28.5171102661597, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI118766330, Length=208, Percent_Identity=29.8076923076923, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI118766328, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=241, Percent_Identity=27.8008298755187, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115532690, Length=241, Percent_Identity=27.8008298755187, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17647755, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24585827, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24585829, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47595; Mature: 47595

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAPQPLTEPLQQAIAAHRSGQLEHAAQLYTQLLDDQPAHADALHYQGILLHQRGNSAA
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCCHH
AVASITQALTLAPAQPDACNNLGNVHRECGRLRDAEHCYRRALALAPAHADALANLAAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
EAQRRSEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQAAEHLQQSVQCLQQACTLAPD
HHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCH
HLHAREALGTGLYLLGEHAQAQTVYRDWLTLEPGNPVATHMLAACGGAEPPPRAGDTYVR
HHHHHHHHCCCCEEECCCHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHH
ELFDGFADSFDEQLLHHLEYRAPQRLTKALAACLAPPHAGLRMLDAGCGTGLCAPLWRPY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHH
AHQLVGVDLSPGMVAKARQRGGYDRLEVAELTAYLHAQHAQWDVIGSADTLVYFGALQPV
HHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHH
LAAAAGALTPGGVLGFTVEALDEPDDRVELDASGRYRHSHAHVRAALQGAGLQPIALELD
HHHHHCCCCCCCHHEEEHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VLRSERGQPVHGWVVTARTPGPA
HHHCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MQTAPQPLTEPLQQAIAAHRSGQLEHAAQLYTQLLDDQPAHADALHYQGILLHQRGNSAA
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCCHH
AVASITQALTLAPAQPDACNNLGNVHRECGRLRDAEHCYRRALALAPAHADALANLAAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
EAQRRSEEAFVTYAALLHTYPQSAHAHYLLGLFLRNNAQAAEHLQQSVQCLQQACTLAPD
HHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCH
HLHAREALGTGLYLLGEHAQAQTVYRDWLTLEPGNPVATHMLAACGGAEPPPRAGDTYVR
HHHHHHHHCCCCEEECCCHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHH
ELFDGFADSFDEQLLHHLEYRAPQRLTKALAACLAPPHAGLRMLDAGCGTGLCAPLWRPY
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHH
AHQLVGVDLSPGMVAKARQRGGYDRLEVAELTAYLHAQHAQWDVIGSADTLVYFGALQPV
HHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHH
LAAAAGALTPGGVLGFTVEALDEPDDRVELDASGRYRHSHAHVRAALQGAGLQPIALELD
HHHHHCCCCCCCHHEEEHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
VLRSERGQPVHGWVVTARTPGPA
HHHCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA