BacMap

Definition	Xanthomonas campestris pv. vesicatoria str. 85-10 chromosome, complete genome.
Accession	NC_007508
Length	5,178,466

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The map label for this gene is fabG [H]

Identifier: 78049734

GI number: 78049734

Start: 4790777

End: 4791508

Strand: Reverse

Name: fabG [H]

Synonym: XCV4178

Alternate gene names: 78049734

Gene position: 4791508-4790777 (Counterclockwise)

Preceding gene: 78049736

Following gene: 78049727

Centisome position: 92.53

GC content: 66.39

Gene sequence:

>732_bases
ATGAACTCAGCTGCAAGACGCGCACTCGTTACCGGCGGCAGCGGCGATCTTGGCGGTGCGATCTGCCGCCACCTGGCTGC
GCAGGGCCTGCATGTCATCGTGCACGCCAATCGCAATCTGGCGCGTGCGGACGAGGTGGTTGCCGCGATCGTGGCCGATG
GCGGCAGCGCACAGGCAGTGGCCTTCGATGTGGCCGACGCGCAGGCAAGTTCGGCGGCGCTGGAGAGCTTGCTGGACGCT
GGCCCGATCCAGATCGTGGTCAACAACGCGGGCATCCATGACGACGCGCCGATGGCAGGCATGAATGCCGAGCAGTGGCA
CCGCGTCATCGACGTGTCGCTGCACGGTTTTTTCAATGTCACCCAGCCGTTGCTGCTGCCGATGGCGCGCACGCGTTGGG
GCCGCATCGTCAGCGTGTCGTCGGTGGCGGCCGTGCTGGGTAACCGCGGGCAGACCAACTACGCCGCCGCCAAGGCGGCG
TTGCACGGCGCCAGCAAGTCGCTCTCGCGCGAAATGGCCAGCCGCGGTATCGCAGTGAATGTGGTCGCGCCGGGCGTGAT
CGATAGCGACATGGTCGGCGACAGTTTCGCGCCGGAGGTGATCAAGCAATTGGTGCCGGCCGGCCGCGTCGGCAAGCCCG
ATGAAGTGGCCGCGCTGGTCGCCTTTTTGTGCTCGGACGCGGCCGGTTACATCAATGGCCAGGTGATCGGCGTCAATGGT
GGGATGGGCTGA

Upstream 100 bases:

>100_bases
CATGGTCAGGCAAATACGCGAGAAGTACCAAGAGTCCGTCCTTCAACGGGCAGCTTGATCTACGATAACGCTCCTTCTCT
GCTCATATGGTTCGTGGCTT

Downstream 100 bases:

>100_bases
GGGCGACTACCAAAACTACTGCGCAGCCGCCAGGCGGGCGCGGCCGGTGCTCGGAATCCTCATGTACAACTCGTACACTC
CGGTTCCTGTGCGCCGTCCA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNSAARRALVTGGSGDLGGAICRHLAAQGLHVIVHANRNLARADEVVAAIVADGGSAQAVAFDVADAQASSAALESLLDA
GPIQIVVNNAGIHDDAPMAGMNAEQWHRVIDVSLHGFFNVTQPLLLPMARTRWGRIVSVSSVAAVLGNRGQTNYAAAKAA
LHGASKSLSREMASRGIAVNVVAPGVIDSDMVGDSFAPEVIKQLVPAGRVGKPDEVAALVAFLCSDAAGYINGQVIGVNG
GMG

Sequences:

>Translated_243_residues
MNSAARRALVTGGSGDLGGAICRHLAAQGLHVIVHANRNLARADEVVAAIVADGGSAQAVAFDVADAQASSAALESLLDA
GPIQIVVNNAGIHDDAPMAGMNAEQWHRVIDVSLHGFFNVTQPLLLPMARTRWGRIVSVSSVAAVLGNRGQTNYAAAKAA
LHGASKSLSREMASRGIAVNVVAPGVIDSDMVGDSFAPEVIKQLVPAGRVGKPDEVAALVAFLCSDAAGYINGQVIGVNG
GMG
>Mature_243_residues
MNSAARRALVTGGSGDLGGAICRHLAAQGLHVIVHANRNLARADEVVAAIVADGGSAQAVAFDVADAQASSAALESLLDA
GPIQIVVNNAGIHDDAPMAGMNAEQWHRVIDVSLHGFFNVTQPLLLPMARTRWGRIVSVSSVAAVLGNRGQTNYAAAKAA
LHGASKSLSREMASRGIAVNVVAPGVIDSDMVGDSFAPEVIKQLVPAGRVGKPDEVAALVAFLCSDAAGYINGQVIGVNG
GMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=35.2226720647773, Blast_Score=121, Evalue=4e-28,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=32.3886639676113, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=35.5932203389831, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=33.6, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=31.4741035856574, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4504505, Length=232, Percent_Identity=33.6206896551724, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=28.2786885245902, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI4503301, Length=197, Percent_Identity=32.994923857868, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=27.8688524590164, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=31.3131313131313, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=29.0076335877863, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=26.865671641791, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=200, Percent_Identity=28.5, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI59889578, Length=177, Percent_Identity=29.3785310734463, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=24.8868778280543, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI66933014, Length=168, Percent_Identity=25, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=43.1451612903226, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=36.0655737704918, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=30.6122448979592, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=31.8181818181818, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=33.6, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=31.1475409836066, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786812, Length=192, Percent_Identity=34.375, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=30.7377049180328, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=27.3809523809524, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789208, Length=240, Percent_Identity=27.0833333333333, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=30.4878048780488, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=35.7429718875502, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=34.9397590361446, Blast_Score=130, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=34.156378600823, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17568967, Length=232, Percent_Identity=35.7758620689655, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17536651, Length=246, Percent_Identity=31.7073170731707, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=32.2448979591837, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=29.1828793774319, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=30.6201550387597, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=30.9160305343511, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=29.5719844357977, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=29.6153846153846, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=29.9610894941634, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=31.0483870967742, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=256, Percent_Identity=33.203125, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=29.3172690763052, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=28.9156626506024, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=31.1284046692607, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=30, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=210, Percent_Identity=31.4285714285714, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=28.957528957529, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=29.1828793774319, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=29.7709923664122, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=28.957528957529, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=29.4573643410853, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=255, Percent_Identity=29.0196078431373, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=30.7392996108949, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=26.8421052631579, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=259, Percent_Identity=26.2548262548263, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=258, Percent_Identity=27.5193798449612, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=30.2127659574468, Blast_Score=104, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=40.8730158730159, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=34.1463414634146, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=30.5220883534137, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=34.5528455284553, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=33.739837398374, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=28.2258064516129, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI18859837, Length=232, Percent_Identity=31.4655172413793, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=31.2252964426877, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.8804780876494, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=31.3609467455621, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24701; Mature: 24701

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSAARRALVTGGSGDLGGAICRHLAAQGLHVIVHANRNLARADEVVAAIVADGGSAQAV
CCHHHCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHEEECCCCCEEE
AFDVADAQASSAALESLLDAGPIQIVVNNAGIHDDAPMAGMNAEQWHRVIDVSLHGFFNV
EEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHH
TQPLLLPMARTRWGRIVSVSSVAAVLGNRGQTNYAAAKAALHGASKSLSREMASRGIAVN
HHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VVAPGVIDSDMVGDSFAPEVIKQLVPAGRVGKPDEVAALVAFLCSDAAGYINGQVIGVNG
EEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECC
GMG
CCC
>Mature Secondary Structure
MNSAARRALVTGGSGDLGGAICRHLAAQGLHVIVHANRNLARADEVVAAIVADGGSAQAV
CCHHHCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHEEECCCCCEEE
AFDVADAQASSAALESLLDAGPIQIVVNNAGIHDDAPMAGMNAEQWHRVIDVSLHGFFNV
EEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHH
TQPLLLPMARTRWGRIVSVSSVAAVLGNRGQTNYAAAKAALHGASKSLSREMASRGIAVN
HHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VVAPGVIDSDMVGDSFAPEVIKQLVPAGRVGKPDEVAALVAFLCSDAAGYINGQVIGVNG
EEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECC
GMG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]