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The map label for this gene is cysJ [H]

Identifier: 78049684

GI number: 78049684

Start: 4723640

End: 4725616

Strand: Reverse

Name: cysJ [H]

Synonym: XCV4128

Alternate gene names: 78049684

Gene position: 4725616-4723640 (Counterclockwise)

Preceding gene: 78049685

Following gene: 78049682

Centisome position: 91.26

GC content: 66.97

Gene sequence:

>1977_bases
TTGTGGAGCCTGCACGCGGTGTTCGGCACCTGGTGCTTGCTGGTGTATTTGCTGGTCGCGCTGACCGGGCTGACCTGGTC
CTACCCCTGGTATCGCGATGGCATGATGGCCTTGCTTGACGGCCTGCCTGCGATACGCGGCGACAAAGGCGATAACCGCC
CGGCCACCGTCGATCTTGCACGCGTGCAGCGCACGCTCGATGGCATTCCCGCCACGCGCAGCGCCGCCCTGGATCTGCGC
ATTCCCGCGCGCGCCGGGCAGCCGTTGAATGTGCGGTTCTTGCCCGACCATCCCGCTCACGATCGCGCCTACAACAGTCT
TGATATCGCGCCGGACAGCGGAGCACTGCTGCAGCGCCTGGACTACGCGCTGCTGCCGCGCGGGCAGCAATTGGCGGCGA
GCATGTTCCCGCTGCATTCGGGCAGTTTCTTCGGGTTGCCCGGGCGCATCGTGGTGATGCTCGCCAGCCTGGGCATGTCG
GTGTTCTTCGTCACCGGCTGGATGCTGTATCTGGATCGGCGCCGCAAAAAACGCGAACTGCGCGCTGCGCGCAAGGTGTT
GCAAGACGCAGCACCGGCCTCGCAAGCGGCGCCGTGGTTGATTGCGTTTGCCAGCCAGAGCGGTTTTGCCGAGCGCCTGG
CGTGGCAGGCCGCCGGGCATCTGCAGGCCGCCGGCTTGCCGGTGCAGGTGTGCTCGCTGGCGCAGCTGGATGCGCAGGCG
CTACAACGCACCGGGCATGCGCTGTTTGTGATCAGCACGTTTGGCGATGGCGAGCCACCGGATGCGGCACGCGGTTTCGA
GCGTGGGCTGCTGCGGCAACGCCTGCAATTGCCGCACCTGACCTACGCGGTGCTGGCGCTGGGAGACCGCCAATATGCGC
AGTTCTGCGGGTTCTCGCGGCGTGTCGAACAGTGGCTGGATGCGCAAGGTGCACGCGCGCTGTTTCCTGCGGTGGAACTG
GATAACGTCGACCCGCAGGCGCTGGCGCAATGGCATGCGCAGCTGGGCCAGATCGCCGGTGCACCTTTGCGCGTGGCGCC
GCTGGCACGGCCCAAATTGAGCGAATGGACCCTGTCTTCGCGCATGCATCTGAATCCGGGCAGCGAGGGGGCGCCGATCT
GGCGCGTCGATCTGCAGCCGCCTGCCGATGCGCAGTGGCAGGCCGGCGACATCCTCGAAGTGCAGCCTGCGCATGCCCAA
GCACAGGTGCGCGCCTGTCTGGCGGCATGGGGCCTGGCGCCGGACGCACTGGTGCACGTGGATGCGCAGCTGCTGCCATT
GCAGCAGGCTGCCGCCGAGCGCGTCCTGCCCGAGCCGCCCGCAACGCCGCTTGCCCATCGCCCTGATCCGCAGACCTGGC
TGGATGCTTGCGCCTGGCTGCCCACACGCGATTATTCGCTCGCCAGCGTACCGGCTGACGGCACCGCGATGGTGGTGGTG
CGGCTGACGGCGCGTGCCGATGGCAGTCCCGGTCTGGGTTCGGGGTGGTTGATCTGCCATGCGGCGATCGGCACGCCGGT
GCGCGCACGGTTGCGCACCAATCCCGGGTTTCATCGGCTCGAAACAATGCCGATGGTCTTGATCGGTAACGGCACCGGCA
TTGCGGGCCTGCGCGCGCTGCTACGCGAGGCCGAGTTGGCCGGCGTGCATGGGCACTGGTTGTTGTTCGGCGAACGGCAT
GCGGCGCACGACCGCCTGTTCGCCGACGAGCTGCAGGCCTGGCAGGCGAGCGGGCATCTGCAGCAGCTGGAGTGGGTGTT
CTCGCGCGATCAACCACAAAAACGCTATGTGCAACATCACTTGCGCGACGCCGGCGACACGCTGCGACACTGGATCGACC
GCGGCGCGGTCATTTACGTCTGCGGCAGTCTGGACAGCATGGCGCGCGAGGTCGATGCAACCTTGCGAGAACTGCTCGGC
GACACGCGATTGGAATCGCTGACCGCGGCCGGCCGTTATCGACGCGATGTGTATTGA

Upstream 100 bases:

>100_bases
GTTCTTCTGCGCATCGGGGCTGTATCTGCGCTGGCCGCGACGGTGGTGGAGCCCGCGCACCTGGTGGGTGGTGTAATGGC
GACGGCAGGGGCGCAGTTTT

Downstream 100 bases:

>100_bases
GCGCGGCGCTGATGGCGCCAGCCCCGCCTTACATCGGCTAGCAGAACCTGGCGAGTGAGCATTGTGCGGGTGCGCAGAGT
AGAGAGCCGCAGACCACCGT

Product: Iron uptake factor (C-terminal fragment)

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMMALLDGLPAIRGDKGDNRPATVDLARVQRTLDGIPATRSAALDLR
IPARAGQPLNVRFLPDHPAHDRAYNSLDIAPDSGALLQRLDYALLPRGQQLAASMFPLHSGSFFGLPGRIVVMLASLGMS
VFFVTGWMLYLDRRRKKRELRAARKVLQDAAPASQAAPWLIAFASQSGFAERLAWQAAGHLQAAGLPVQVCSLAQLDAQA
LQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLQLPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQGARALFPAVEL
DNVDPQALAQWHAQLGQIAGAPLRVAPLARPKLSEWTLSSRMHLNPGSEGAPIWRVDLQPPADAQWQAGDILEVQPAHAQ
AQVRACLAAWGLAPDALVHVDAQLLPLQQAAAERVLPEPPATPLAHRPDPQTWLDACAWLPTRDYSLASVPADGTAMVVV
RLTARADGSPGLGSGWLICHAAIGTPVRARLRTNPGFHRLETMPMVLIGNGTGIAGLRALLREAELAGVHGHWLLFGERH
AAHDRLFADELQAWQASGHLQQLEWVFSRDQPQKRYVQHHLRDAGDTLRHWIDRGAVIYVCGSLDSMAREVDATLRELLG
DTRLESLTAAGRYRRDVY

Sequences:

>Translated_658_residues
MWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMMALLDGLPAIRGDKGDNRPATVDLARVQRTLDGIPATRSAALDLR
IPARAGQPLNVRFLPDHPAHDRAYNSLDIAPDSGALLQRLDYALLPRGQQLAASMFPLHSGSFFGLPGRIVVMLASLGMS
VFFVTGWMLYLDRRRKKRELRAARKVLQDAAPASQAAPWLIAFASQSGFAERLAWQAAGHLQAAGLPVQVCSLAQLDAQA
LQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLQLPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQGARALFPAVEL
DNVDPQALAQWHAQLGQIAGAPLRVAPLARPKLSEWTLSSRMHLNPGSEGAPIWRVDLQPPADAQWQAGDILEVQPAHAQ
AQVRACLAAWGLAPDALVHVDAQLLPLQQAAAERVLPEPPATPLAHRPDPQTWLDACAWLPTRDYSLASVPADGTAMVVV
RLTARADGSPGLGSGWLICHAAIGTPVRARLRTNPGFHRLETMPMVLIGNGTGIAGLRALLREAELAGVHGHWLLFGERH
AAHDRLFADELQAWQASGHLQQLEWVFSRDQPQKRYVQHHLRDAGDTLRHWIDRGAVIYVCGSLDSMAREVDATLRELLG
DTRLESLTAAGRYRRDVY
>Mature_658_residues
MWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMMALLDGLPAIRGDKGDNRPATVDLARVQRTLDGIPATRSAALDLR
IPARAGQPLNVRFLPDHPAHDRAYNSLDIAPDSGALLQRLDYALLPRGQQLAASMFPLHSGSFFGLPGRIVVMLASLGMS
VFFVTGWMLYLDRRRKKRELRAARKVLQDAAPASQAAPWLIAFASQSGFAERLAWQAAGHLQAAGLPVQVCSLAQLDAQA
LQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLQLPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQGARALFPAVEL
DNVDPQALAQWHAQLGQIAGAPLRVAPLARPKLSEWTLSSRMHLNPGSEGAPIWRVDLQPPADAQWQAGDILEVQPAHAQ
AQVRACLAAWGLAPDALVHVDAQLLPLQQAAAERVLPEPPATPLAHRPDPQTWLDACAWLPTRDYSLASVPADGTAMVVV
RLTARADGSPGLGSGWLICHAAIGTPVRARLRTNPGFHRLETMPMVLIGNGTGIAGLRALLREAELAGVHGHWLLFGERH
AAHDRLFADELQAWQASGHLQQLEWVFSRDQPQKRYVQHHLRDAGDTLRHWIDRGAVIYVCGSLDSMAREVDATLRELLG
DTRLESLTAAGRYRRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI221316709, Length=196, Percent_Identity=32.6530612244898, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI7657393, Length=202, Percent_Identity=32.6732673267327, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI127139033, Length=151, Percent_Identity=33.112582781457, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI221316705, Length=211, Percent_Identity=31.7535545023697, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI169790956, Length=173, Percent_Identity=32.3699421965318, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI169790958, Length=173, Percent_Identity=32.3699421965318, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI221316707, Length=181, Percent_Identity=33.1491712707182, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789123, Length=539, Percent_Identity=28.2003710575139, Blast_Score=151, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17554134, Length=225, Percent_Identity=31.5555555555556, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17566446, Length=200, Percent_Identity=29.5, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321143, Length=237, Percent_Identity=25.7383966244726, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 72246; Mature: 72246

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMMALLDGLPAIRGDKGDNRPATVDLA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCEEHHH
RVQRTLDGIPATRSAALDLRIPARAGQPLNVRFLPDHPAHDRAYNSLDIAPDSGALLQRL
HHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
DYALLPRGQQLAASMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRRRKKREL
HHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAARKVLQDAAPASQAAPWLIAFASQSGFAERLAWQAAGHLQAAGLPVQVCSLAQLDAQA
HHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHH
LQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLQLPHLTYAVLALGDRQYAQFCGFSR
HHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHH
RVEQWLDAQGARALFPAVELDNVDPQALAQWHAQLGQIAGAPLRVAPLARPKLSEWTLSS
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCC
RMHLNPGSEGAPIWRVDLQPPADAQWQAGDILEVQPAHAQAQVRACLAAWGLAPDALVHV
EEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHEEC
DAQLLPLQQAAAERVLPEPPATPLAHRPDPQTWLDACAWLPTRDYSLASVPADGTAMVVV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEEE
RLTARADGSPGLGSGWLICHAAIGTPVRARLRTNPGFHRLETMPMVLIGNGTGIAGLRAL
EEEECCCCCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHCCCCEEEEECCCCHHHHHHH
LREAELAGVHGHWLLFGERHAAHDRLFADELQAWQASGHLQQLEWVFSRDQPQKRYVQHH
HHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
LRDAGDTLRHWIDRGAVIYVCGSLDSMAREVDATLRELLGDTRLESLTAAGRYRRDVY
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMMALLDGLPAIRGDKGDNRPATVDLA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCEEHHH
RVQRTLDGIPATRSAALDLRIPARAGQPLNVRFLPDHPAHDRAYNSLDIAPDSGALLQRL
HHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
DYALLPRGQQLAASMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRRRKKREL
HHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAARKVLQDAAPASQAAPWLIAFASQSGFAERLAWQAAGHLQAAGLPVQVCSLAQLDAQA
HHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHH
LQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLQLPHLTYAVLALGDRQYAQFCGFSR
HHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHH
RVEQWLDAQGARALFPAVELDNVDPQALAQWHAQLGQIAGAPLRVAPLARPKLSEWTLSS
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCC
RMHLNPGSEGAPIWRVDLQPPADAQWQAGDILEVQPAHAQAQVRACLAAWGLAPDALVHV
EEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHEEC
DAQLLPLQQAAAERVLPEPPATPLAHRPDPQTWLDACAWLPTRDYSLASVPADGTAMVVV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEEE
RLTARADGSPGLGSGWLICHAAIGTPVRARLRTNPGFHRLETMPMVLIGNGTGIAGLRAL
EEEECCCCCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHCCCCEEEEECCCCHHHHHHH
LREAELAGVHGHWLLFGERHAAHDRLFADELQAWQASGHLQQLEWVFSRDQPQKRYVQHH
HHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
LRDAGDTLRHWIDRGAVIYVCGSLDSMAREVDATLRELLGDTRLESLTAAGRYRRDVY
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA