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The map label for this gene is catB [H]

Identifier: 78049678

GI number: 78049678

Start: 4716315

End: 4717838

Strand: Reverse

Name: catB [H]

Synonym: XCV4122

Alternate gene names: 78049678

Gene position: 4717838-4716315 (Counterclockwise)

Preceding gene: 78049679

Following gene: 78049677

Centisome position: 91.1

GC content: 61.81

Gene sequence:

>1524_bases
ATGCGCCCTGGACACCTCATGGTGCTAGCCCTGCTAGCCCCGACGTTGATCGCTCCGCCGGTCTTCGCCCAATCCGTTCT
GACCCGCGACAATGGGGCCAAGGTCGGCGATAACCAGAATTCGCAGACAGCCGGTGCCACCGGCCCGACGCTGCTGCAGG
ACGTGCAGCTGATCCAGAAGCTGCAGCGTTTCGATCGCGAACGCATTCCCGAGCGCGTGGTGCATGCGCGCGGCACTGGC
GTCAAAGGCGAGTTCACCGCCACTGCCGATCTCTCCAGCCTGACCAAGGCCAAGGTCTTCAGCGCCGGCGAAAAAACTCC
GGTGTTCGTGCGCTTTTCTTCGGTAGTCCATGGCAACCATTCGCCGGAGACGCTGCGCGACCCGCATGGTTTCGCTACCA
AGTTCTATACCAGCGAAGGCAATTGGGATCTGGTCGGCAACAACTTCCCCACCTTCTTCATTCGCGATGCGATCAAGTTC
CCCGACATGGTGCACGCGTTCAAGCCGGACCCGCGCACTAATCTGGATGACGATTCGCGTCGCTTCGATTTCTTCTCGCA
CGTGCCAGAAGCCACGCGCACGCTGACCCTGCTGTACTCCAACGAGGGCACTCCGGCCGGCTATCGCTTCATGGACGGCA
ATGGCGTACACGCCTACAAGCTGGTCAACGCGCAGGGTGAAGTGCACTACGTCAAGTTCCATTGGAAGACGCTGCAGGGC
ATCAAGAACCTCGATCCCAAGCAGGTCGCCGCGGTGCAGGCCAAGGACTACAGCCACCTGACCAACGATCTGGTCGCTGC
GATCAAGAAGGGCGATTACCCGAAATGGGATTTGTACGTGCAGGTGCTCAAGCCGGAAGACCTGGCCAAGTTCGATTTCG
ACCCGCTTGACGCCACCAAGATCTGGCCGGACGTGCCGGAGCAGAAGGTCGGCCAGATGGTGTTGAACAAGAACGTCGAT
AATTTCTTCCAGGAAACCGAGCAGGTGGCCATGGCGCCGGCCAATCTGGTGCCGGGCATCGAACCTTCGGAAGACCGCCT
GTTGCAGGGCCGCATCTTCTCCTACGCCGACACCCAGCTGTATCGCATCGGTGCCAATGGGCTGAGCCTGCCGGTCAATC
GCCCGCGTGTAGCTGTCAACAACGGCAACCAGGACGGCCAGGGCAACATCGGCCAGACCACCAGTGGGGTGAACTACGAG
CCGAGCCGCCTGGAGCCGCGTCCGCAGGACACCGCTGCGCGCTACAGCGAGCTGCCGCTGTCGGGCACCACCCAGCAGGC
CAAGATCACCCGCGAGCAGAACTTCAAGCAGGCCGGCGAGTTGTATCGCTCCTACAGCAAGAAGGACCGTGCCGATCTGG
TGCAGAGCTTCGGTGAGTCGCTGGCCACCACCGACCCCGAAAGCAAGCACCTGATGCTGTCGTTCCTGTACAAGGCCGAC
CCCGAGTACGGTACCGGCGTCACCCGCGTGGCCAAGGGCGATTTGGCGCGGGTCAAGCAGTTGGCCTCCAGCCTGCAGGA
CTGA

Upstream 100 bases:

>100_bases
CAGTCATCATCATCTTCCCCTATCGAAGCGATCATAACTAACGACTTCTCACACTCCGGCCTGCTAGCGATGATTCAGCC
TCCTCAAACGAGCTGACGCC

Downstream 100 bases:

>100_bases
TCCGCCCGACGACATCGCGGCCTGCGCCGCGGTGTCGTCTTTACTTCGGGAGATCCCTATGCGCACCCTGTTGTTTCTGA
TGCTTGGCAGCGTGTCTGCG

Product: catalase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MRPGHLMVLALLAPTLIAPPVFAQSVLTRDNGAKVGDNQNSQTAGATGPTLLQDVQLIQKLQRFDRERIPERVVHARGTG
VKGEFTATADLSSLTKAKVFSAGEKTPVFVRFSSVVHGNHSPETLRDPHGFATKFYTSEGNWDLVGNNFPTFFIRDAIKF
PDMVHAFKPDPRTNLDDDSRRFDFFSHVPEATRTLTLLYSNEGTPAGYRFMDGNGVHAYKLVNAQGEVHYVKFHWKTLQG
IKNLDPKQVAAVQAKDYSHLTNDLVAAIKKGDYPKWDLYVQVLKPEDLAKFDFDPLDATKIWPDVPEQKVGQMVLNKNVD
NFFQETEQVAMAPANLVPGIEPSEDRLLQGRIFSYADTQLYRIGANGLSLPVNRPRVAVNNGNQDGQGNIGQTTSGVNYE
PSRLEPRPQDTAARYSELPLSGTTQQAKITREQNFKQAGELYRSYSKKDRADLVQSFGESLATTDPESKHLMLSFLYKAD
PEYGTGVTRVAKGDLARVKQLASSLQD

Sequences:

>Translated_507_residues
MRPGHLMVLALLAPTLIAPPVFAQSVLTRDNGAKVGDNQNSQTAGATGPTLLQDVQLIQKLQRFDRERIPERVVHARGTG
VKGEFTATADLSSLTKAKVFSAGEKTPVFVRFSSVVHGNHSPETLRDPHGFATKFYTSEGNWDLVGNNFPTFFIRDAIKF
PDMVHAFKPDPRTNLDDDSRRFDFFSHVPEATRTLTLLYSNEGTPAGYRFMDGNGVHAYKLVNAQGEVHYVKFHWKTLQG
IKNLDPKQVAAVQAKDYSHLTNDLVAAIKKGDYPKWDLYVQVLKPEDLAKFDFDPLDATKIWPDVPEQKVGQMVLNKNVD
NFFQETEQVAMAPANLVPGIEPSEDRLLQGRIFSYADTQLYRIGANGLSLPVNRPRVAVNNGNQDGQGNIGQTTSGVNYE
PSRLEPRPQDTAARYSELPLSGTTQQAKITREQNFKQAGELYRSYSKKDRADLVQSFGESLATTDPESKHLMLSFLYKAD
PEYGTGVTRVAKGDLARVKQLASSLQD
>Mature_507_residues
MRPGHLMVLALLAPTLIAPPVFAQSVLTRDNGAKVGDNQNSQTAGATGPTLLQDVQLIQKLQRFDRERIPERVVHARGTG
VKGEFTATADLSSLTKAKVFSAGEKTPVFVRFSSVVHGNHSPETLRDPHGFATKFYTSEGNWDLVGNNFPTFFIRDAIKF
PDMVHAFKPDPRTNLDDDSRRFDFFSHVPEATRTLTLLYSNEGTPAGYRFMDGNGVHAYKLVNAQGEVHYVKFHWKTLQG
IKNLDPKQVAAVQAKDYSHLTNDLVAAIKKGDYPKWDLYVQVLKPEDLAKFDFDPLDATKIWPDVPEQKVGQMVLNKNVD
NFFQETEQVAMAPANLVPGIEPSEDRLLQGRIFSYADTQLYRIGANGLSLPVNRPRVAVNNGNQDGQGNIGQTTSGVNYE
PSRLEPRPQDTAARYSELPLSGTTQQAKITREQNFKQAGELYRSYSKKDRADLVQSFGESLATTDPESKHLMLSFLYKAD
PEYGTGVTRVAKGDLARVKQLASSLQD

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=468, Percent_Identity=42.7350427350427, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI48994891, Length=387, Percent_Identity=46.7700258397933, Blast_Score=346, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI25147792, Length=467, Percent_Identity=41.7558886509636, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI25151141, Length=467, Percent_Identity=41.541755888651, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71998444, Length=467, Percent_Identity=41.9700214132762, Blast_Score=379, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320462, Length=491, Percent_Identity=36.8635437881874, Blast_Score=303, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6321525, Length=343, Percent_Identity=43.731778425656, Blast_Score=288, Evalue=1e-78,
Organism=Drosophila melanogaster, GI17981717, Length=446, Percent_Identity=44.1704035874439, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19920968, Length=448, Percent_Identity=42.1875, Blast_Score=358, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 56358; Mature: 56358

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGHLMVLALLAPTLIAPPVFAQSVLTRDNGAKVGDNQNSQTAGATGPTLLQDVQLIQK
CCCCCEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LQRFDRERIPERVVHARGTGVKGEFTATADLSSLTKAKVFSAGEKTPVFVRFSSVVHGNH
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCC
SPETLRDPHGFATKFYTSEGNWDLVGNNFPTFFIRDAIKFPDMVHAFKPDPRTNLDDDSR
CCHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCCHH
RFDFFSHVPEATRTLTLLYSNEGTPAGYRFMDGNGVHAYKLVNAQGEVHYVKFHWKTLQG
HHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEEEEHHHHH
IKNLDPKQVAAVQAKDYSHLTNDLVAAIKKGDYPKWDLYVQVLKPEDLAKFDFDPLDATK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHCCCCCCCCHH
IWPDVPEQKVGQMVLNKNVDNFFQETEQVAMAPANLVPGIEPSEDRLLQGRIFSYADTQL
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHEEECCCEE
YRIGANGLSLPVNRPRVAVNNGNQDGQGNIGQTTSGVNYEPSRLEPRPQDTAARYSELPL
EEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
SGTTQQAKITREQNFKQAGELYRSYSKKDRADLVQSFGESLATTDPESKHLMLSFLYKAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
PEYGTGVTRVAKGDLARVKQLASSLQD
CCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPGHLMVLALLAPTLIAPPVFAQSVLTRDNGAKVGDNQNSQTAGATGPTLLQDVQLIQK
CCCCCEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LQRFDRERIPERVVHARGTGVKGEFTATADLSSLTKAKVFSAGEKTPVFVRFSSVVHGNH
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCC
SPETLRDPHGFATKFYTSEGNWDLVGNNFPTFFIRDAIKFPDMVHAFKPDPRTNLDDDSR
CCHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCCHH
RFDFFSHVPEATRTLTLLYSNEGTPAGYRFMDGNGVHAYKLVNAQGEVHYVKFHWKTLQG
HHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEEEEHHHHH
IKNLDPKQVAAVQAKDYSHLTNDLVAAIKKGDYPKWDLYVQVLKPEDLAKFDFDPLDATK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHCCCCCCCCHH
IWPDVPEQKVGQMVLNKNVDNFFQETEQVAMAPANLVPGIEPSEDRLLQGRIFSYADTQL
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHEEECCCEE
YRIGANGLSLPVNRPRVAVNNGNQDGQGNIGQTTSGVNYEPSRLEPRPQDTAARYSELPL
EEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
SGTTQQAKITREQNFKQAGELYRSYSKKDRADLVQSFGESLATTDPESKHLMLSFLYKAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
PEYGTGVTRVAKGDLARVKQLASSLQD
CCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7546603 [H]