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The map label for this gene is desR [H]

Identifier: 78049642

GI number: 78049642

Start: 4681478

End: 4682095

Strand: Reverse

Name: desR [H]

Synonym: XCV4086

Alternate gene names: 78049642

Gene position: 4682095-4681478 (Counterclockwise)

Preceding gene: 78049643

Following gene: 78049641

Centisome position: 90.41

GC content: 67.48

Gene sequence:

>618_bases
ATGCGAGCGCGACCGATGATCCGGGTGTTGTTGGCGGAAGACCAAGCCTTGCTGCGTGGCGCGCTGGTGGCCTTGCTCGG
ACTGGAGGACGATATTGCGGTGGTCGGCAGCGCCGGCGATGGCGAAAGCGCGTGGCGCGAACTGCAGCGCCTGCAGCCGG
ACGTGCTGGTCACCGATATCGAGATGCCTGGCCTGACCGGGCTGGAACTGGCGCAGCGGATCCAGCGCCAGGCGTTGCCG
GTACGGGTCATGATCGTCACCACGTTCGCGCGTCCGGGATTTTTGCGCCGTGCCCTGGATGCCGGCGTGGCCGGGTATCT
GCTCAAGGATGCGCCGGCCGAACAGCTGGTCGATGCGTTGCGGCAGGTGCACCGCGGCGGGCGGGTGATCGACCCGCAGC
TGGCCCTCGATGCGTGGGTGGAAGCAGACCCCTTGAGCGAACGCGAACGGACTGTGCTGCGGCTGGCCGGCGAAGGCCGC
TCCGCCAGCGAGATCGCCCAGCAGTTGCAGCTCTCGCACGGCACGGTGCGCAATTACCTGTCCGAATGCATCGGCAAACT
GGGCGTGGCCAATCGCATCGAAGCCTACCGCCTGGCGCGGCAGAAGGGCTGGTTGTAG

Upstream 100 bases:

>100_bases
AACGCCGCCGGTGATGCCGCAGCCGCTCTAACGCGCCGTGGTTGCGCTGCCAAGTGCACGGCATGCGTCGGCGCTGTTAT
CGTGCGCAACCGTTGCATGC

Downstream 100 bases:

>100_bases
TGCAGCCAGTCGATGGTTTGCGTGCGCGGGAAGCTGACGTTTTCGGGGTGCGGGATTGCATGCAGGTGCGCCGCGCCTAA
TCGACGCGAGCGCACCACAA

Product: LuxR family two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MRARPMIRVLLAEDQALLRGALVALLGLEDDIAVVGSAGDGESAWRELQRLQPDVLVTDIEMPGLTGLELAQRIQRQALP
VRVMIVTTFARPGFLRRALDAGVAGYLLKDAPAEQLVDALRQVHRGGRVIDPQLALDAWVEADPLSERERTVLRLAGEGR
SASEIAQQLQLSHGTVRNYLSECIGKLGVANRIEAYRLARQKGWL

Sequences:

>Translated_205_residues
MRARPMIRVLLAEDQALLRGALVALLGLEDDIAVVGSAGDGESAWRELQRLQPDVLVTDIEMPGLTGLELAQRIQRQALP
VRVMIVTTFARPGFLRRALDAGVAGYLLKDAPAEQLVDALRQVHRGGRVIDPQLALDAWVEADPLSERERTVLRLAGEGR
SASEIAQQLQLSHGTVRNYLSECIGKLGVANRIEAYRLARQKGWL
>Mature_205_residues
MRARPMIRVLLAEDQALLRGALVALLGLEDDIAVVGSAGDGESAWRELQRLQPDVLVTDIEMPGLTGLELAQRIQRQALP
VRVMIVTTFARPGFLRRALDAGVAGYLLKDAPAEQLVDALRQVHRGGRVIDPQLALDAWVEADPLSERERTVLRLAGEGR
SASEIAQQLQLSHGTVRNYLSECIGKLGVANRIEAYRLARQKGWL

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=33.1730769230769, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=34.6534653465347, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=31.8840579710145, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=23.0392156862745, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787473, Length=198, Percent_Identity=32.3232323232323, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=25.2475247524752, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788546, Length=196, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22515; Mature: 22515

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARPMIRVLLAEDQALLRGALVALLGLEDDIAVVGSAGDGESAWRELQRLQPDVLVTDI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEC
EMPGLTGLELAQRIQRQALPVRVMIVTTFARPGFLRRALDAGVAGYLLKDAPAEQLVDAL
CCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCHHHHHHHH
RQVHRGGRVIDPQLALDAWVEADPLSERERTVLRLAGEGRSASEIAQQLQLSHGTVRNYL
HHHHHCCCEECHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
SECIGKLGVANRIEAYRLARQKGWL
HHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRARPMIRVLLAEDQALLRGALVALLGLEDDIAVVGSAGDGESAWRELQRLQPDVLVTDI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEC
EMPGLTGLELAQRIQRQALPVRVMIVTTFARPGFLRRALDAGVAGYLLKDAPAEQLVDAL
CCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCHHHHHHHH
RQVHRGGRVIDPQLALDAWVEADPLSERERTVLRLAGEGRSASEIAQQLQLSHGTVRNYL
HHHHHCCCEECHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
SECIGKLGVANRIEAYRLARQKGWL
HHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]