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The map label for this gene is ctaC [H]

Identifier: 78049562

GI number: 78049562

Start: 4595243

End: 4596202

Strand: Reverse

Name: ctaC [H]

Synonym: XCV4006

Alternate gene names: 78049562

Gene position: 4596202-4595243 (Counterclockwise)

Preceding gene: 78049563

Following gene: 78049561

Centisome position: 88.76

GC content: 65.1

Gene sequence:

>960_bases
ATGACGCAACGCAGCAGCTGGAAGTCGATCAACACCTGCACACACGTGGGCCTGGCGATGGCGGCGCTGCTGAGCGCGCC
GGTGGCCTGGGCGCAATCGGCCGATCCCAAGGAATGGCAGCTCAACATGGGGCGCGGAGTGACCCAGACCGCGCGGATGG
CCTACGAGGCGCACATGGTGGCGCTGTGGGTGTGCGTGGTGATTGGCGCGCTGGTGTTCTCGGCGATGGGCTATGCGATG
TTCAAGTTCCGCAAGTCCAAGGGCGCGGTGGCCGCACAATTCAGTCACAACACCACCGCGGAAGTGCTGTGGACGGTGAT
TCCGGTCCTGGTGCTGATTGCGATGGCGTGGCCGGCGACGGCAAAACTGATCGCGATGTACGACACCCGCGAATCGGAAA
TGACGGTCAAGGTGACCGGCTATCAGTGGATGTGGAAGTACGAATATCTGGGCCAGGGCGTGGAATTCACCAGCCGCCTG
GCACGCGAATCCGATCGTATCCGCCAAAGCGGCGAGCGCCCCACCGCGGCCTCGCAGCCGCACTATCTGCTGGATGTCGA
TAACCGCCTGGTGCTGCCGGTCAACACCAAGATCCGCTTCGTGATTACCGCCGACGATGTGATCCACGCCTGGTGGGTGC
CGGCGCTGGGATGGAAGCAAGATGCCATTCCCGGCATCGTCAACGAAGCCTGGACCAACATCGAGCAACCGGGCGTGTAT
CGCGGGCAGTGCGCCGAGTTGTGCGGCAAGGATCATGGCTTCATGCCGATCGTGGTGGAGGCGCTGCCCAAGGCTGACTT
CCAGCGCTGGCTAGCGTCGCGTCGTAGCGCGTCAGGCACTGCTCCGGGAGCGGCGCCAGCGGCCGCACCGACGCCGACCA
GTGCACCGGCCGCTCCGCAAGGTGACGCCGCGCCTGCGGCGACACCGGCCCAGGCCGCAACACCGACCGCCGCTCTTTAA

Upstream 100 bases:

>100_bases
AGTTTTCTCGGGCCGGCCGAACGTGTGGAACTGGCAATAACGCTCAAACGCTTGCTCGCGGCCGCCAATGGCCGTCACCG
ATGACGTAAGGGTCTAGGCA

Downstream 100 bases:

>100_bases
TCGCCCGCAATCGCTCGCTTCGCAGAGGTCGTTCCGTCATGGCGCATACCGCAGTCGATCACCACGGACACCACCAGCCC
GGTTTCGTCGAGCGCTGGTT

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTQRSSWKSINTCTHVGLAMAALLSAPVAWAQSADPKEWQLNMGRGVTQTARMAYEAHMVALWVCVVIGALVFSAMGYAM
FKFRKSKGAVAAQFSHNTTAEVLWTVIPVLVLIAMAWPATAKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVEFTSRL
ARESDRIRQSGERPTAASQPHYLLDVDNRLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
RGQCAELCGKDHGFMPIVVEALPKADFQRWLASRRSASGTAPGAAPAAAPTPTSAPAAPQGDAAPAATPAQAATPTAAL

Sequences:

>Translated_319_residues
MTQRSSWKSINTCTHVGLAMAALLSAPVAWAQSADPKEWQLNMGRGVTQTARMAYEAHMVALWVCVVIGALVFSAMGYAM
FKFRKSKGAVAAQFSHNTTAEVLWTVIPVLVLIAMAWPATAKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVEFTSRL
ARESDRIRQSGERPTAASQPHYLLDVDNRLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
RGQCAELCGKDHGFMPIVVEALPKADFQRWLASRRSASGTAPGAAPAAAPTPTSAPAAPQGDAAPAATPAQAATPTAAL
>Mature_318_residues
TQRSSWKSINTCTHVGLAMAALLSAPVAWAQSADPKEWQLNMGRGVTQTARMAYEAHMVALWVCVVIGALVFSAMGYAMF
KFRKSKGAVAAQFSHNTTAEVLWTVIPVLVLIAMAWPATAKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVEFTSRLA
RESDRIRQSGERPTAASQPHYLLDVDNRLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVYR
GQCAELCGKDHGFMPIVVEALPKADFQRWLASRRSASGTAPGAAPAAAPTPTSAPAAPQGDAAPAATPAQAATPTAAL

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=170, Percent_Identity=41.1764705882353, Blast_Score=143, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6226540, Length=226, Percent_Identity=38.4955752212389, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 34626; Mature: 34495

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRSSWKSINTCTHVGLAMAALLSAPVAWAQSADPKEWQLNMGRGVTQTARMAYEAHMV
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHH
ALWVCVVIGALVFSAMGYAMFKFRKSKGAVAAQFSHNTTAEVLWTVIPVLVLIAMAWPAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCH
AKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVEFTSRLARESDRIRQSGERPTAASQP
HEEEEEEECCCCCEEEEEECEEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
HYLLDVDNRLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
CEEEECCCEEEEEECCEEEEEEEECHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCC
RGQCAELCGKDHGFMPIVVEALPKADFQRWLASRRSASGTAPGAAPAAAPTPTSAPAAPQ
CHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GDAAPAATPAQAATPTAAL
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQRSSWKSINTCTHVGLAMAALLSAPVAWAQSADPKEWQLNMGRGVTQTARMAYEAHMV
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHH
ALWVCVVIGALVFSAMGYAMFKFRKSKGAVAAQFSHNTTAEVLWTVIPVLVLIAMAWPAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCH
AKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVEFTSRLARESDRIRQSGERPTAASQP
HEEEEEEECCCCCEEEEEECEEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
HYLLDVDNRLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
CEEEECCCEEEEEECCEEEEEEEECHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCC
RGQCAELCGKDHGFMPIVVEALPKADFQRWLASRRSASGTAPGAAPAAAPTPTSAPAAPQ
CHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GDAAPAATPAQAATPTAAL
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA