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The map label for this gene is ctaD [H]

Identifier: 78049561

GI number: 78049561

Start: 4593600

End: 4595204

Strand: Reverse

Name: ctaD [H]

Synonym: XCV4005

Alternate gene names: 78049561

Gene position: 4595204-4593600 (Counterclockwise)

Preceding gene: 78049562

Following gene: 78049560

Centisome position: 88.74

GC content: 61.68

Gene sequence:

>1605_bases
ATGGCGCATACCGCAGTCGATCACCACGGACACCACCAGCCCGGTTTCGTCGAGCGCTGGTTCTTTTCGACCAATCACAA
GGATATCGGCACGTTGTATCTGCTGTTTTCCTTCGTGATGTTCATCATCGGCGCGGCGATGAGCGTGGTGATTCGCGCCG
AATTGATGCAGCCCGGCTTGCAGTTCGTCAAACCGGAGTTCTTCAACCAGATGACCACCGTGCATGCACTGGTGATGATC
TTCGGCGGCGTGATGCCGGCTTTCGTCGGCTTGGCCAACTGGATGATTCCGTTGCAGATCGGTGCGCCGGACATGGCGTT
GCCGCGTATGAACAACTGGTCGTTCTGGTTGTTGCCGGTCGCCTTTACCCTGCTGCTGCTGACGCTGTTCCTGCCGGGCG
GCGCGCCGGCAGGCGGCTGGACGCTGTACCCGCCGCTGTCGCTGCAGGGCGGCTACAACGTCGCCTTCAGCGTGTTTGCG
ATCCACGTGGCCGGCGTCAGCTCGATCATGGGCGCGATCAACATCATCGCCACCGTGCTGAACATGCGCGCGCCAGGCAT
CGATCTGCTCAAGATGCCGATCTTCTGCTGGGCCTGGCTGATCACCGCGTTCCTGCTGATCGCGGTGATGCCGGTGCTGG
CCGGCGCGGTGACCATGCTGCTGACCGACAAGTTCTTCGGTACCAGCTTCTTCAACGCGGCCGGCGGCGGCGACCCGGTG
ATGTACCAGCACATCTTCTGGTTCTTCGGGCACCCGGAGGTGTACATCATGATCCTGCCGGCGTTCGGCGTGGTCAGCGA
GATCATTCCGACCTTTAGCCGCAAGCCGCTGTTCGGTTACCAGGCGATGGTCTACGCCATTGCCGCGATCGCCTTCCTGA
GCTTCATCGTCTGGGCCCACCACATGTTCACCGTGGGCATGCCGCTGGGCGGCGAAATTTATTTCATGTTCGCCACCATG
CTGATCTCCATCCCGACCGGGGTGAAGGTGTTCAACTGGGTCAGCACGATGTGGAAGGGCTCGCTGACCTTCGAATCGCC
GATGTTGTGGGCGGTGGCGTTCGTGATCCTCTTCAGCATCGGTGGGTTCTCCGGCCTGATGCTGGCGATCGTGCCGGCCG
ACTTCCAGTACCACGACACCTACTTCGTGGTGGCGCACTTCCACTACGTGCTGGTGACCGGTGCGGTGTTCGCGCTGATC
GCGGCGGTGTACTACTGGTGGCCCAAGTGGACCGGGCGGATGTACAACGAGACCTGGGCCAAGGTGCACTTCTGGTGGAC
GATGGTGTTCGTCAACCTGCTGTTCTTCCCGCAGCACTTCCTTGGCTTGGCCGGCATGCCGCGGCGCATTCCCGACTACA
ACGTGGTGTTTGCCGACTGGAATCTGGTCAGTTCGATCGGTGCGTTCGGCATGTTCGTCACGCCGTTCCTGATGGCCGCG
ATCCTGCTGTCCTCGCTGCGCAGTGGCGCGCGTGCACAGGCCCGCTCCTGGGAAGGTGCCAAGGGTCTGGAATGGACGGT
GCCGTCACCTGCCCCGGCGCATACCTTCACCGTGCCGCCGGTGATCAAGCCTGGAGATCTTGCACATGAAGACATCGGCC
ACTGA

Upstream 100 bases:

>100_bases
AAGGTGACGCCGCGCCTGCGGCGACACCGGCCCAGGCCGCAACACCGACCGCCGCTCTTTAATCGCCCGCAATCGCTCGC
TTCGCAGAGGTCGTTCCGTC

Downstream 100 bases:

>100_bases
GTCCGCCTCGGAGCCGGCGGTGACGCGTCTGTTATCTGCTGCGGAACGGCAGGCGCAGCAGCGCCGTGCGGTACGCCGTA
CCGCGATCACGGTCGGCATC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MAHTAVDHHGHHQPGFVERWFFSTNHKDIGTLYLLFSFVMFIIGAAMSVVIRAELMQPGLQFVKPEFFNQMTTVHALVMI
FGGVMPAFVGLANWMIPLQIGAPDMALPRMNNWSFWLLPVAFTLLLLTLFLPGGAPAGGWTLYPPLSLQGGYNVAFSVFA
IHVAGVSSIMGAINIIATVLNMRAPGIDLLKMPIFCWAWLITAFLLIAVMPVLAGAVTMLLTDKFFGTSFFNAAGGGDPV
MYQHIFWFFGHPEVYIMILPAFGVVSEIIPTFSRKPLFGYQAMVYAIAAIAFLSFIVWAHHMFTVGMPLGGEIYFMFATM
LISIPTGVKVFNWVSTMWKGSLTFESPMLWAVAFVILFSIGGFSGLMLAIVPADFQYHDTYFVVAHFHYVLVTGAVFALI
AAVYYWWPKWTGRMYNETWAKVHFWWTMVFVNLLFFPQHFLGLAGMPRRIPDYNVVFADWNLVSSIGAFGMFVTPFLMAA
ILLSSLRSGARAQARSWEGAKGLEWTVPSPAPAHTFTVPPVIKPGDLAHEDIGH

Sequences:

>Translated_534_residues
MAHTAVDHHGHHQPGFVERWFFSTNHKDIGTLYLLFSFVMFIIGAAMSVVIRAELMQPGLQFVKPEFFNQMTTVHALVMI
FGGVMPAFVGLANWMIPLQIGAPDMALPRMNNWSFWLLPVAFTLLLLTLFLPGGAPAGGWTLYPPLSLQGGYNVAFSVFA
IHVAGVSSIMGAINIIATVLNMRAPGIDLLKMPIFCWAWLITAFLLIAVMPVLAGAVTMLLTDKFFGTSFFNAAGGGDPV
MYQHIFWFFGHPEVYIMILPAFGVVSEIIPTFSRKPLFGYQAMVYAIAAIAFLSFIVWAHHMFTVGMPLGGEIYFMFATM
LISIPTGVKVFNWVSTMWKGSLTFESPMLWAVAFVILFSIGGFSGLMLAIVPADFQYHDTYFVVAHFHYVLVTGAVFALI
AAVYYWWPKWTGRMYNETWAKVHFWWTMVFVNLLFFPQHFLGLAGMPRRIPDYNVVFADWNLVSSIGAFGMFVTPFLMAA
ILLSSLRSGARAQARSWEGAKGLEWTVPSPAPAHTFTVPPVIKPGDLAHEDIGH
>Mature_533_residues
AHTAVDHHGHHQPGFVERWFFSTNHKDIGTLYLLFSFVMFIIGAAMSVVIRAELMQPGLQFVKPEFFNQMTTVHALVMIF
GGVMPAFVGLANWMIPLQIGAPDMALPRMNNWSFWLLPVAFTLLLLTLFLPGGAPAGGWTLYPPLSLQGGYNVAFSVFAI
HVAGVSSIMGAINIIATVLNMRAPGIDLLKMPIFCWAWLITAFLLIAVMPVLAGAVTMLLTDKFFGTSFFNAAGGGDPVM
YQHIFWFFGHPEVYIMILPAFGVVSEIIPTFSRKPLFGYQAMVYAIAAIAFLSFIVWAHHMFTVGMPLGGEIYFMFATML
ISIPTGVKVFNWVSTMWKGSLTFESPMLWAVAFVILFSIGGFSGLMLAIVPADFQYHDTYFVVAHFHYVLVTGAVFALIA
AVYYWWPKWTGRMYNETWAKVHFWWTMVFVNLLFFPQHFLGLAGMPRRIPDYNVVFADWNLVSSIGAFGMFVTPFLMAAI
LLSSLRSGARAQARSWEGAKGLEWTVPSPAPAHTFTVPPVIKPGDLAHEDIGH

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=50.8771929824561, Blast_Score=476, Evalue=1e-134,
Organism=Escherichia coli, GI1786634, Length=520, Percent_Identity=40.1923076923077, Blast_Score=378, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226519, Length=532, Percent_Identity=45.6766917293233, Blast_Score=479, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=49.0740740740741, Blast_Score=323, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=44.578313253012, Blast_Score=207, Evalue=5e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59419; Mature: 59288

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTAVDHHGHHQPGFVERWFFSTNHKDIGTLYLLFSFVMFIIGAAMSVVIRAELMQPGL
CCCCCCCCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QFVKPEFFNQMTTVHALVMIFGGVMPAFVGLANWMIPLQIGAPDMALPRMNNWSFWLLPV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCEEHHHH
AFTLLLLTLFLPGGAPAGGWTLYPPLSLQGGYNVAFSVFAIHVAGVSSIMGAINIIATVL
HHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMRAPGIDLLKMPIFCWAWLITAFLLIAVMPVLAGAVTMLLTDKFFGTSFFNAAGGGDPV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCH
MYQHIFWFFGHPEVYIMILPAFGVVSEIIPTFSRKPLFGYQAMVYAIAAIAFLSFIVWAH
HHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HMFTVGMPLGGEIYFMFATMLISIPTGVKVFNWVSTMWKGSLTFESPMLWAVAFVILFSI
HHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
GGFSGLMLAIVPADFQYHDTYFVVAHFHYVLVTGAVFALIAAVYYWWPKWTGRMYNETWA
CCHHCEEEEEEECCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KVHFWWTMVFVNLLFFPQHFLGLAGMPRRIPDYNVVFADWNLVSSIGAFGMFVTPFLMAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
ILLSSLRSGARAQARSWEGAKGLEWTVPSPAPAHTFTVPPVIKPGDLAHEDIGH
HHHHHHHCCCHHHHCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AHTAVDHHGHHQPGFVERWFFSTNHKDIGTLYLLFSFVMFIIGAAMSVVIRAELMQPGL
CCCCCCCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QFVKPEFFNQMTTVHALVMIFGGVMPAFVGLANWMIPLQIGAPDMALPRMNNWSFWLLPV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCEEHHHH
AFTLLLLTLFLPGGAPAGGWTLYPPLSLQGGYNVAFSVFAIHVAGVSSIMGAINIIATVL
HHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMRAPGIDLLKMPIFCWAWLITAFLLIAVMPVLAGAVTMLLTDKFFGTSFFNAAGGGDPV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCH
MYQHIFWFFGHPEVYIMILPAFGVVSEIIPTFSRKPLFGYQAMVYAIAAIAFLSFIVWAH
HHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HMFTVGMPLGGEIYFMFATMLISIPTGVKVFNWVSTMWKGSLTFESPMLWAVAFVILFSI
HHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
GGFSGLMLAIVPADFQYHDTYFVVAHFHYVLVTGAVFALIAAVYYWWPKWTGRMYNETWA
CCHHCEEEEEEECCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KVHFWWTMVFVNLLFFPQHFLGLAGMPRRIPDYNVVFADWNLVSSIGAFGMFVTPFLMAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
ILLSSLRSGARAQARSWEGAKGLEWTVPSPAPAHTFTVPPVIKPGDLAHEDIGH
HHHHHHHCCCHHHHCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8117073 [H]