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The map label for this gene is sndH2

Identifier: 78049358

GI number: 78049358

Start: 4387260

End: 4388597

Strand: Reverse

Name: sndH2

Synonym: XCV3802

Alternate gene names: NA

Gene position: 4388597-4387260 (Counterclockwise)

Preceding gene: 78049359

Following gene: 78049356

Centisome position: 84.75

GC content: 65.92

Gene sequence:

>1338_bases
ATGAATGCATCCCGATTGAAGTTCGCTCGCTGGCCGCTGTCGTTGATGGCGCTGGCCGTCCTCGCCGCGTGCGGCGACAC
GGCAACATTGGCGATCGAACAGGGAACCGGGCCGGACCCGCAATTGCCCGAGCCGGTGAAGCGTCTGATTCCCACCGTCA
AGGTGGCGCCGGTCAAACGCTGGGCAGCCAATGCCAAGCCCATCGCGGCCGACGATCTGCAGGTTGCTGCGTTTGCGCGC
GATCTGGATCACCCGCGCTGGGTCTACGTGCTGCCCAATGGCGATGTGTTGGTGGCCGAAACGGCCGAGCCGCCCAAGCC
CGAGGATGCCGAAGCGGGCGGTGGGCTGCGCAAGAAAGTGCAGGGCGCGATGATGAAAAAGGCCGGCGCGGCGGTGGCGA
GCGCCAATCGCATCACCTTGCTGCGCGAGGCCGACGGCGACGGCGTGGCAGAAGTGCGCACGCAGTTCGTCAGCGGGCTG
TTTTCGCCGTTCGGCATGGCGCTGATCGGCGACCGCTTCTATGTCGCCAACGCCGATGCGCTGGTGAGTTTTCCGTACAA
GCCCGGCGACACGCATCTCACCGCCAAGCCGACTTTCGTGGCCAATCTGCCCGGCGGCATCAACCATCACTGGACCAAGT
CGCTGCTGGCCAGCCCGGACGGCAGCAAGCTCTATGTCGGCGTCGGTTCCAACAGCAACGTGGCCGAAAACGGCATGGAA
GCCGAGCTCAATCGTGCGGCGATCCTGGAAATCGACCCGGCCACCGGCAGCAGCCGCGTCTTCGCCGGCGGCTTGCGCAA
CCCGGTGGGCACCGCATGGGAGCCGCAGAGCAAATCGCTGTGGGTGGTGGTCAACGAGCGCGACGAGATCGGCAGCGACC
TGGTGCCGGACTACCTCACCTCGGTGCGCGACGGCGGTTTCTACGGCTGGCCGTACAGCTACTACGGCCAGCATGTGGAC
GAGCGGGTCAAACCGCAGAATGCCGAACTGGTGGCCAAGGCGATCAAGCCCGATTACGCGCTCGGCCCGCATACCGCATC
GCTCGGCCTGAGCTTCGCCAGCGGTACCTTGTTGCCCGAGCGTTTCCGCCAGGGCGCCTTCATCGGCCAGCACGGCTCGT
GGAATCGCGACCCGCCCAGCGGCTACAAGGTGTTGTTTGTCCCGTTCGCCGATGGCAAGCCCAACGGCCCGCCGATCACG
GTGCTGGATGGATTCCTGGATGCCGAAGGCAATGCGCAGGGCCGCCCGGTGGGTGTGGCATCTGACAGTCGCGGCGCACT
GCTGGTGGCCGACGATGTGGGCAATGTGATCTGGCAGGTGACGCCGAAGGCGCGTTGA

Upstream 100 bases:

>100_bases
GTCATGCCGTGACGGTGGTGTGTTGACGGTGTGTTTACTTCTCGCCGTCGCGTTGGCGGCATGATCGCTGGCTGACGCAA
CCGTCCAGGATTTGCCCGCA

Downstream 100 bases:

>100_bases
GCCGACAGCGGGCCGCGTGGCCAAGTGGACTAGCCCCTTCAGCGAGGCACCTCCGGCGAGGCGCAGAAGCGACGCGCATA
TCCCCTTTCTTCGGCAACGC

Product: L-sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNASRLKFARWPLSLMALAVLAACGDTATLAIEQGTGPDPQLPEPVKRLIPTVKVAPVKRWAANAKPIAADDLQVAAFAR
DLDHPRWVYVLPNGDVLVAETAEPPKPEDAEAGGGLRKKVQGAMMKKAGAAVASANRITLLREADGDGVAEVRTQFVSGL
FSPFGMALIGDRFYVANADALVSFPYKPGDTHLTAKPTFVANLPGGINHHWTKSLLASPDGSKLYVGVGSNSNVAENGME
AELNRAAILEIDPATGSSRVFAGGLRNPVGTAWEPQSKSLWVVVNERDEIGSDLVPDYLTSVRDGGFYGWPYSYYGQHVD
ERVKPQNAELVAKAIKPDYALGPHTASLGLSFASGTLLPERFRQGAFIGQHGSWNRDPPSGYKVLFVPFADGKPNGPPIT
VLDGFLDAEGNAQGRPVGVASDSRGALLVADDVGNVIWQVTPKAR

Sequences:

>Translated_445_residues
MNASRLKFARWPLSLMALAVLAACGDTATLAIEQGTGPDPQLPEPVKRLIPTVKVAPVKRWAANAKPIAADDLQVAAFAR
DLDHPRWVYVLPNGDVLVAETAEPPKPEDAEAGGGLRKKVQGAMMKKAGAAVASANRITLLREADGDGVAEVRTQFVSGL
FSPFGMALIGDRFYVANADALVSFPYKPGDTHLTAKPTFVANLPGGINHHWTKSLLASPDGSKLYVGVGSNSNVAENGME
AELNRAAILEIDPATGSSRVFAGGLRNPVGTAWEPQSKSLWVVVNERDEIGSDLVPDYLTSVRDGGFYGWPYSYYGQHVD
ERVKPQNAELVAKAIKPDYALGPHTASLGLSFASGTLLPERFRQGAFIGQHGSWNRDPPSGYKVLFVPFADGKPNGPPIT
VLDGFLDAEGNAQGRPVGVASDSRGALLVADDVGNVIWQVTPKAR
>Mature_445_residues
MNASRLKFARWPLSLMALAVLAACGDTATLAIEQGTGPDPQLPEPVKRLIPTVKVAPVKRWAANAKPIAADDLQVAAFAR
DLDHPRWVYVLPNGDVLVAETAEPPKPEDAEAGGGLRKKVQGAMMKKAGAAVASANRITLLREADGDGVAEVRTQFVSGL
FSPFGMALIGDRFYVANADALVSFPYKPGDTHLTAKPTFVANLPGGINHHWTKSLLASPDGSKLYVGVGSNSNVAENGME
AELNRAAILEIDPATGSSRVFAGGLRNPVGTAWEPQSKSLWVVVNERDEIGSDLVPDYLTSVRDGGFYGWPYSYYGQHVD
ERVKPQNAELVAKAIKPDYALGPHTASLGLSFASGTLLPERFRQGAFIGQHGSWNRDPPSGYKVLFVPFADGKPNGPPIT
VLDGFLDAEGNAQGRPVGVASDSRGALLVADDVGNVIWQVTPKAR

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 47320; Mature: 47320

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASRLKFARWPLSLMALAVLAACGDTATLAIEQGTGPDPQLPEPVKRLIPTVKVAPVKR
CCCCCCCHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHCCCEEEECHHH
WAANAKPIAADDLQVAAFARDLDHPRWVYVLPNGDVLVAETAEPPKPEDAEAGGGLRKKV
HCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHH
QGAMMKKAGAAVASANRITLLREADGDGVAEVRTQFVSGLFSPFGMALIGDRFYVANADA
HHHHHHHHCHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCE
LVSFPYKPGDTHLTAKPTFVANLPGGINHHWTKSLLASPDGSKLYVGVGSNSNVAENGME
EEECCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHCCCCC
AELNRAAILEIDPATGSSRVFAGGLRNPVGTAWEPQSKSLWVVVNERDEIGSDLVPDYLT
CCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCHHCCCCHHHHHHH
SVRDGGFYGWPYSYYGQHVDERVKPQNAELVAKAIKPDYALGPHTASLGLSFASGTLLPE
HHCCCCEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCHHCCCCCHH
RFRQGAFIGQHGSWNRDPPSGYKVLFVPFADGKPNGPPITVLDGFLDAEGNAQGRPVGVA
HHHCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECEECCCCCCCCCEEEEC
SDSRGALLVADDVGNVIWQVTPKAR
CCCCCEEEEEECCCCEEEEECCCCC
>Mature Secondary Structure
MNASRLKFARWPLSLMALAVLAACGDTATLAIEQGTGPDPQLPEPVKRLIPTVKVAPVKR
CCCCCCCHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHCCCEEEECHHH
WAANAKPIAADDLQVAAFARDLDHPRWVYVLPNGDVLVAETAEPPKPEDAEAGGGLRKKV
HCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHH
QGAMMKKAGAAVASANRITLLREADGDGVAEVRTQFVSGLFSPFGMALIGDRFYVANADA
HHHHHHHHCHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCE
LVSFPYKPGDTHLTAKPTFVANLPGGINHHWTKSLLASPDGSKLYVGVGSNSNVAENGME
EEECCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHCCCCC
AELNRAAILEIDPATGSSRVFAGGLRNPVGTAWEPQSKSLWVVVNERDEIGSDLVPDYLT
CCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCHHCCCCHHHHHHH
SVRDGGFYGWPYSYYGQHVDERVKPQNAELVAKAIKPDYALGPHTASLGLSFASGTLLPE
HHCCCCEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCHHCCCCCHH
RFRQGAFIGQHGSWNRDPPSGYKVLFVPFADGKPNGPPITVLDGFLDAEGNAQGRPVGVA
HHHCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECEECCCCCCCCCEEEEC
SDSRGALLVADDVGNVIWQVTPKAR
CCCCCEEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]