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The map label for this gene is cobA [H]

Identifier: 78048876

GI number: 78048876

Start: 3797840

End: 3798451

Strand: Reverse

Name: cobA [H]

Synonym: XCV3320

Alternate gene names: 78048876

Gene position: 3798451-3797840 (Counterclockwise)

Preceding gene: 78048877

Following gene: 78048875

Centisome position: 73.35

GC content: 65.03

Gene sequence:

>612_bases
ATGACCACCCCCGAGCACGATGAGGCGCATTACCGCGAACGTGCGCAGCGCAAGAAGGAATTGGTCGACCGGCGCATCGC
ACGTGCAGTGATCGACCGCGGTGTGCTGCTGGTCAATACCGGCAATGGCAAGGGCAAGAGCTCGTCCGGCTTCGGCATGC
TGGCGCGCTCGCTTGGGCATGGCCTGCATTGCGGCGTGGTGCAATTCATCAAGGGCACGTTTTCGACCGGCGAAGAAGCG
TTTTTCCGTCGCTTTCCGGATCTGCTCGATTATCACGTCATGGGCGAAGGCTTCACCTGGGAAACCCAGGACCGCGCACG
CGACATCGCCGCCACGCAGGCGGCCTGGCAGCGTGCGCGCGGCATGCTGGCCGATGCGCGCTACGATTTCGTGCTGCTGG
ACGAACTCAACATCGCCCTGGTGAAGGACTACATCGCGCTGGATGAGGTGCTTGCTGCCGTGGCCGCGCGGCCGCCCGGC
CAGCACGTGGTGATCACCGGGCGCGGCGCGCCGGCCGGGTTGATCGAGGTCGCCGACACCGTGACCGAGATGCGCCTGGT
CAAGCACGCCTTCAATGCCGGCATCAAGGCGCAACTCGGCATCGAGCTGTAG

Upstream 100 bases:

>100_bases
TACACGCCCTTGCAACACTGGCCGGCTATATCGGCCTGGCTTTCGCCCTGTTGGCTGCACACCGCGCCGCTGGTGCACGT
CCACCCATGGGAGCACGCGC

Downstream 100 bases:

>100_bases
CCGTGGGCGTGCGCGCGCAATGCCTTGCATGGCTCGGCATGTTGGCTGGCATGCGCCGGGACTGCACGCCATGCTGCTGG
TGACTGCCACCGTTGCCGTG

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTTPEHDEAHYRERAQRKKELVDRRIARAVIDRGVLLVNTGNGKGKSSSGFGMLARSLGHGLHCGVVQFIKGTFSTGEEA
FFRRFPDLLDYHVMGEGFTWETQDRARDIAATQAAWQRARGMLADARYDFVLLDELNIALVKDYIALDEVLAAVAARPPG
QHVVITGRGAPAGLIEVADTVTEMRLVKHAFNAGIKAQLGIEL

Sequences:

>Translated_203_residues
MTTPEHDEAHYRERAQRKKELVDRRIARAVIDRGVLLVNTGNGKGKSSSGFGMLARSLGHGLHCGVVQFIKGTFSTGEEA
FFRRFPDLLDYHVMGEGFTWETQDRARDIAATQAAWQRARGMLADARYDFVLLDELNIALVKDYIALDEVLAAVAARPPG
QHVVITGRGAPAGLIEVADTVTEMRLVKHAFNAGIKAQLGIEL
>Mature_202_residues
TTPEHDEAHYRERAQRKKELVDRRIARAVIDRGVLLVNTGNGKGKSSSGFGMLARSLGHGLHCGVVQFIKGTFSTGEEAF
FRRFPDLLDYHVMGEGFTWETQDRARDIAATQAAWQRARGMLADARYDFVLLDELNIALVKDYIALDEVLAAVAARPPGQ
HVVITGRGAPAGLIEVADTVTEMRLVKHAFNAGIKAQLGIEL

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=192, Percent_Identity=51.5625, Blast_Score=204, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22342; Mature: 22211

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPEHDEAHYRERAQRKKELVDRRIARAVIDRGVLLVNTGNGKGKSSSGFGMLARSLGH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCC
GLHCGVVQFIKGTFSTGEEAFFRRFPDLLDYHVMGEGFTWETQDRARDIAATQAAWQRAR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
GMLADARYDFVLLDELNIALVKDYIALDEVLAAVAARPPGQHVVITGRGAPAGLIEVADT
CCHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
VTEMRLVKHAFNAGIKAQLGIEL
HHHHHHHHHHHCCCCEEECCCCC
>Mature Secondary Structure 
TTPEHDEAHYRERAQRKKELVDRRIARAVIDRGVLLVNTGNGKGKSSSGFGMLARSLGH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCC
GLHCGVVQFIKGTFSTGEEAFFRRFPDLLDYHVMGEGFTWETQDRARDIAATQAAWQRAR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
GMLADARYDFVLLDELNIALVKDYIALDEVLAAVAARPPGQHVVITGRGAPAGLIEVADT
CCHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
VTEMRLVKHAFNAGIKAQLGIEL
HHHHHHHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]