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The map label for this gene is cobU [H]

Identifier: 78048872

GI number: 78048872

Start: 3793795

End: 3794319

Strand: Reverse

Name: cobU [H]

Synonym: XCV3316

Alternate gene names: 78048872

Gene position: 3794319-3793795 (Counterclockwise)

Preceding gene: 78048873

Following gene: 78048871

Centisome position: 73.27

GC content: 66.1

Gene sequence:

>525_bases
ATGCAGCAACTGATTCTTGGCGGCGCCCGTTCGGGCAAGAGCGCGCTGGCCGAGCGCATCGCGGCAGGGTCCGGGCGCGC
AGTGACTTACCTGGCCACAGCGCAAGCCTTCGATGGCGAAATGCATCGGCGCATTGCCCATCACCGCAGCGAACGCCCCG
CGCATTGGCAGTGCGTGGAAGAGCCCATCGCGCTGGCGGCGACCTTGCAGGCGCATGCCGCGCCGGATCGCTGCGTGCTG
GTGGATTGCCTGACCCTGTGGCTGAGCAATCTGCTCGGCCACCCGGATGCAGGCATGTTCGCGCGCGAGCGCGATGCGCT
GCTGGCAACGCTGCCGCAGTTGCCGGGGCAGATCCTGCTGGTCAGCAACGAAGTGGGGCAGGGCATCGTGCCGTTGGGCA
AACTCACGCGTCGGTTTGTGGACGAGGCTGGCTGGCTGCATCAGGCATTGGCGCTACAGTGCGAGCGTGTGGTGTTGGTG
GTGGCAGGATTGCCGATGGTGTTGAAGGAGAGCGCGTGTGAGTAG

Upstream 100 bases:

>100_bases
TTGCCGCGCTGCGCGAAGCCAGCCTGGAGCGTCTGGCCGATGCGGTGCACACGCATCTGGATACCGCGGCACTGACACGC
CTCATCAGCAGGGAACCGGC

Downstream 100 bases:

>100_bases
CGATTGGATTTTTGGTGCCTGCGCAGTGCCGGACGCGCGCATGCGCTCTGCCGCGCTTGCCCGGCAGGAACAGCTGACCA
AGCCGCCCGGCGCATTGGGC

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MQQLILGGARSGKSALAERIAAGSGRAVTYLATAQAFDGEMHRRIAHHRSERPAHWQCVEEPIALAATLQAHAAPDRCVL
VDCLTLWLSNLLGHPDAGMFARERDALLATLPQLPGQILLVSNEVGQGIVPLGKLTRRFVDEAGWLHQALALQCERVVLV
VAGLPMVLKESACE

Sequences:

>Translated_174_residues
MQQLILGGARSGKSALAERIAAGSGRAVTYLATAQAFDGEMHRRIAHHRSERPAHWQCVEEPIALAATLQAHAAPDRCVL
VDCLTLWLSNLLGHPDAGMFARERDALLATLPQLPGQILLVSNEVGQGIVPLGKLTRRFVDEAGWLHQALALQCERVVLV
VAGLPMVLKESACE
>Mature_174_residues
MQQLILGGARSGKSALAERIAAGSGRAVTYLATAQAFDGEMHRRIAHHRSERPAHWQCVEEPIALAATLQAHAAPDRCVL
VDCLTLWLSNLLGHPDAGMFARERDALLATLPQLPGQILLVSNEVGQGIVPLGKLTRRFVDEAGWLHQALALQCERVVLV
VAGLPMVLKESACE

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=182, Percent_Identity=40.1098901098901, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18767; Mature: 18767

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLILGGARSGKSALAERIAAGSGRAVTYLATAQAFDGEMHRRIAHHRSERPAHWQCVE
CCCCEECCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHCHHHHHHHHHHCCCCCCHHHHHH
EPIALAATLQAHAAPDRCVLVDCLTLWLSNLLGHPDAGMFARERDALLATLPQLPGQILL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEE
VSNEVGQGIVPLGKLTRRFVDEAGWLHQALALQCERVVLVVAGLPMVLKESACE
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure
MQQLILGGARSGKSALAERIAAGSGRAVTYLATAQAFDGEMHRRIAHHRSERPAHWQCVE
CCCCEECCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHCHHHHHHHHHHCCCCCCHHHHHH
EPIALAATLQAHAAPDRCVLVDCLTLWLSNLLGHPDAGMFARERDALLATLPQLPGQILL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEE
VSNEVGQGIVPLGKLTRRFVDEAGWLHQALALQCERVVLVVAGLPMVLKESACE
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]