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The map label for this gene is cobT [H]

Identifier: 78048871

GI number: 78048871

Start: 3792756

End: 3793802

Strand: Reverse

Name: cobT [H]

Synonym: XCV3315

Alternate gene names: 78048871

Gene position: 3793802-3792756 (Counterclockwise)

Preceding gene: 78048872

Following gene: 78048870

Centisome position: 73.26

GC content: 69.05

Gene sequence:

>1047_bases
GTGAGTAGCGATTGGATTTTTGGTGCCTGCGCAGTGCCGGACGCGCGCATGCGCTCTGCCGCGCTTGCCCGGCAGGAACA
GCTGACCAAGCCGCCCGGCGCATTGGGCCGGCTGGAACACCTGGCAGTGCGGCTGGCCGCCTGGCAACGCACCGATCGGC
CCGGAGTGCAGCGGGTCTGGATCGCGGTGTATGCCGCCGACCATGGCGTAGCGGCCGAAGGAGTCTCGGCTTTTCCGCAG
GCAGTGACCGGCGAGATGGTGCGCAATTTCGCACGCGGTGGCGCCGCCATTGCGGTACTGGCGCGCGAGTTGGGCGCGCG
GCTGGAAGTGGTGAATCTGGGCGTGGTCAACGACCCCGGCGACCTGCCGCGGGTGCGGCGTGCCTGGATTGCGCCCAGCA
GCGCCAATATCTGCGAGCAGCCGGCGATGACGGCCACCCAATTGCGCGATGCGCTCGCCGCCGGCGCCGACAGCATCGCG
CAGGCCAAGAGTTGCGATACCCAGCTATTTGTCGGCGGCGAGATGGGCATCGGCAACACCACCGCCGCCGCGGCGCTGGG
CTGCGCCTTGCTGTCGCAGTTTCCGCAGGCGATGGCCGGCGCAGGCACCGGCCTGGATGCCGAAGGCATTGCGCACAAGG
CCACCGTGATCACGCGTGCGCTGGCCTTGCATGCCGATGCATCGAGCCCGCTGGAGCGTTTGCGCCGGCTGGGCGGATTC
GAAATCGCTGCCTTGGTCGGCGCCTACATCGCCGCCGCGCAGGCCGGCATCCCGGTGCTGGTGGATGGCTTCATCACCAC
GGCGGCGGCACTGGTGGCCACTCGCCTGAATCCCGGCGTGCGCGAGTGGTTGTTGTTCGGGCATCGCTCGCAGGAGCGTG
GGCATGCAGCGCTGCTGCGCGCAATGGATGCCGAGCCCTTGCTGCAACTGGACCTGCGTCTGGGCGAAGCCAGCGGCGCG
GCGGTGGCGATTCCGCTGCTGCGCAGCGCCTGCGCCTTACATAACGGCATGGCGACGTTTGCCGAAGCCGGGGTGTCGGA
CGCATGA

Upstream 100 bases:

>100_bases
GTGGACGAGGCTGGCTGGCTGCATCAGGCATTGGCGCTACAGTGCGAGCGTGTGGTGTTGGTGGTGGCAGGATTGCCGAT
GGTGTTGAAGGAGAGCGCGT

Downstream 100 bases:

>100_bases
GCGCGCAAATCACCTTGTTGCGGCATGGCGACACCGGGCAACGCAGCTATCGCGGCCAGCTCGACGACCCGCTCACCGAA
CTGGGCTGGCAGCAATTGCG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSSDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEHLAVRLAAWQRTDRPGVQRVWIAVYAADHGVAAEGVSAFPQ
AVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPGDLPRVRRAWIAPSSANICEQPAMTATQLRDALAAGADSIA
QAKSCDTQLFVGGEMGIGNTTAAAALGCALLSQFPQAMAGAGTGLDAEGIAHKATVITRALALHADASSPLERLRRLGGF
EIAALVGAYIAAAQAGIPVLVDGFITTAAALVATRLNPGVREWLLFGHRSQERGHAALLRAMDAEPLLQLDLRLGEASGA
AVAIPLLRSACALHNGMATFAEAGVSDA

Sequences:

>Translated_348_residues
MSSDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEHLAVRLAAWQRTDRPGVQRVWIAVYAADHGVAAEGVSAFPQ
AVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPGDLPRVRRAWIAPSSANICEQPAMTATQLRDALAAGADSIA
QAKSCDTQLFVGGEMGIGNTTAAAALGCALLSQFPQAMAGAGTGLDAEGIAHKATVITRALALHADASSPLERLRRLGGF
EIAALVGAYIAAAQAGIPVLVDGFITTAAALVATRLNPGVREWLLFGHRSQERGHAALLRAMDAEPLLQLDLRLGEASGA
AVAIPLLRSACALHNGMATFAEAGVSDA
>Mature_347_residues
SSDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEHLAVRLAAWQRTDRPGVQRVWIAVYAADHGVAAEGVSAFPQA
VTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPGDLPRVRRAWIAPSSANICEQPAMTATQLRDALAAGADSIAQ
AKSCDTQLFVGGEMGIGNTTAAAALGCALLSQFPQAMAGAGTGLDAEGIAHKATVITRALALHADASSPLERLRRLGGFE
IAALVGAYIAAAQAGIPVLVDGFITTAAALVATRLNPGVREWLLFGHRSQERGHAALLRAMDAEPLLQLDLRLGEASGAA
VAIPLLRSACALHNGMATFAEAGVSDA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=335, Percent_Identity=34.3283582089552, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35968; Mature: 35836

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEHLAVRLAAWQRTDRPGVQRVW
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEE
IAVYAADHGVAAEGVSAFPQAVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEEEEECCCC
DLPRVRRAWIAPSSANICEQPAMTATQLRDALAAGADSIAQAKSCDTQLFVGGEMGIGNT
CCHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHCHHHHHHHHCCCCEEEECCCCCCCCH
TAAAALGCALLSQFPQAMAGAGTGLDAEGIAHKATVITRALALHADASSPLERLRRLGGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCH
EIAALVGAYIAAAQAGIPVLVDGFITTAAALVATRLNPGVREWLLFGHRSQERGHAALLR
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
AMDAEPLLQLDLRLGEASGAAVAIPLLRSACALHNGMATFAEAGVSDA
HCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCHHHHHHCCCCCC
>Mature Secondary Structure 
SSDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEHLAVRLAAWQRTDRPGVQRVW
CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEE
IAVYAADHGVAAEGVSAFPQAVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEEEEECCCC
DLPRVRRAWIAPSSANICEQPAMTATQLRDALAAGADSIAQAKSCDTQLFVGGEMGIGNT
CCHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHCHHHHHHHHCCCCEEEECCCCCCCCH
TAAAALGCALLSQFPQAMAGAGTGLDAEGIAHKATVITRALALHADASSPLERLRRLGGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCH
EIAALVGAYIAAAQAGIPVLVDGFITTAAALVATRLNPGVREWLLFGHRSQERGHAALLR
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
AMDAEPLLQLDLRLGEASGAAVAIPLLRSACALHNGMATFAEAGVSDA
HCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]