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The map label for this gene is yieH [H]

Identifier: 78048593

GI number: 78048593

Start: 3458419

End: 3459123

Strand: Reverse

Name: yieH [H]

Synonym: XCV3037

Alternate gene names: 78048593

Gene position: 3459123-3458419 (Counterclockwise)

Preceding gene: 78048596

Following gene: 78048591

Centisome position: 66.8

GC content: 65.25

Gene sequence:

>705_bases
ATGGCGCTTTGTGAGCAGATGGGTGCGATGGCGTACGAGCTACTGATCAGTGACTGTGATGGCGTTCTTGTCGACAGCGA
GATACTGGCCGACCGGGTAATGCGTGAGGCGCTGGCGTCTTTCGTGCCAAGCGAGCCGCTGGAACAGCTGCTGGAAACCA
CCTTCGGGCAGACCACGCGCGAGGTGCTGCGGCGGGTGGAAGAGCGCTTTGCATTGCAGTTGCCAGAGACCCTGCTCGCG
CAGATCCAGGCGCGCAGCGAGGCCTTGATCCAGGCGCAGGTGCAGCCGATCGCAGGCGTACGCGAGGCGTTGGAGCAGAT
TCCACTGCCGTTGGCGGTGGCCTCCAATAGCCGGCGCCACAATGTGATTGCCTCGGTGGAACGGGCCGGGCTCACCGCAC
GCGCGGCGGGACGTATTTTCAGCGCCGACATGGTGGAGCGGCCCAAGCCGGCACCGGACGTGTATCTGCTGGCGGCACGC
ACCGCCGGAGTCGCGCCGCAGCGTTGTGTGGTCATCGAAGACAGCCCCACCGGTGCAACCGCGGCCGTGACGGCCGGCAT
GCAGGTGCTGGGGTTTACCGGTGCAAGCCACATTCCACCGGGGCATGGCGACACCCTGCGCCGCATCGGTGTGCTTGAAG
TGTTCGACGACATGCGTGATTTGCCTGCGCTGTTCGCGCGGTTGGCGCAAAAGCGGGCTGGGTAA

Upstream 100 bases:

>100_bases
GGGGCCGCCTGTCCTGATGGTGCGCATGCTGCAAGCGGCGACGGTGTCCATCGCCACAGCCTGCTGCCCCACAGCCGACG
GTCACACCCGGGCCGGCATA

Downstream 100 bases:

>100_bases
GGCGGCAGCTTGGTGAGGGGGGGCGGTGTCATGGGTACGCAGTGGCCCCGTCCCGCAAGCGGCGAGGACACCGCGCCGCA
AGGTGTTCGGTTGTCTTGTC

Product: haloacid dehalogenase-like hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MALCEQMGAMAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEQLLETTFGQTTREVLRRVEERFALQLPETLLA
QIQARSEALIQAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAAR
TAGVAPQRCVVIEDSPTGATAAVTAGMQVLGFTGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFARLAQKRAG

Sequences:

>Translated_234_residues
MALCEQMGAMAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEQLLETTFGQTTREVLRRVEERFALQLPETLLA
QIQARSEALIQAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAAR
TAGVAPQRCVVIEDSPTGATAAVTAGMQVLGFTGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFARLAQKRAG
>Mature_233_residues
ALCEQMGAMAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEQLLETTFGQTTREVLRRVEERFALQLPETLLAQ
IQARSEALIQAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAART
AGVAPQRCVVIEDSPTGATAAVTAGMQVLGFTGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFARLAQKRAG

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=189, Percent_Identity=26.4550264550265, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789046, Length=180, Percent_Identity=31.1111111111111, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17137324, Length=183, Percent_Identity=30.0546448087432, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25191; Mature: 25060

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALCEQMGAMAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEQLLETTFGQTTR
CCHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
EVLRRVEERFALQLPETLLAQIQARSEALIQAQVQPIAGVREALEQIPLPLAVASNSRRH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHH
NVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPQRCVVIEDSPTGAT
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCCH
AAVTAGMQVLGFTGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFARLAQKRAG
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALCEQMGAMAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEQLLETTFGQTTR
CHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
EVLRRVEERFALQLPETLLAQIQARSEALIQAQVQPIAGVREALEQIPLPLAVASNSRRH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHH
NVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPQRCVVIEDSPTGAT
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCCH
AAVTAGMQVLGFTGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFARLAQKRAG
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]