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The map label for this gene is amiC [H]

Identifier: 78048159

GI number: 78048159

Start: 2933903

End: 2935603

Strand: Reverse

Name: amiC [H]

Synonym: XCV2603

Alternate gene names: 78048159

Gene position: 2935603-2933903 (Counterclockwise)

Preceding gene: 78048160

Following gene: 78048158

Centisome position: 56.69

GC content: 67.43

Gene sequence:

>1701_bases
ATGACACCGGGGATCCGCCAGTTCTGTCTTTCCGCCCTGACCGCCAGCTTGAGCCTGGCGGTTTTTGCTGCATGGGGCGG
CGAAATCAAGGGGGTTGGCGTCAGTACCGGGGCCACCGGGACCCGTGCAGAAATTCAACTGGCCGGCAGCGGCGGCTTCA
AAACGCTCTCGCTGGCGAACCCGACGCGCCTGGTTGTCGATTTTCCCGAATCCTCGGGCATGCGCGGTCTCAAGCTGCCG
TCCGCTGCCGGATTGGTGACTTCGGTACGCACCGGTCAGCCGGTGCCTGGCACATTCCGTGTGGTGTTCGAACTGGCAAC
GCCGGTGACGCCGCTCAAGCCGCAGATGCAGACGCTGGGTAGCGTGTCGACATTGGTGATCGAATGGCCTGGCGATCCGG
CGCCGGCGGCGGCCTCCGCCGTTGCTGCGGCTGTACCGACGGCAGCCCCGGCGCCGCGTCCGCTCAATGCGCAGGCCGAA
GCTGCACGCGCAACGGCAGCCCTGGCCGCATCTGCGCAACGTGCCTCCTCGGTGCCGCCGTCCCAGCCGTCGACTGCGCC
GCCTGCACCGTCTGTGCCGGCATCGGCGATGCCCACTGTCACTCAGGCCCCGGTACCGACCACTGTCGCTACCGGTGTGC
CGACGCCTCGGCCTGCCACCTCCGGTGCACCAGCGCCGACCGGCGTTACCGGCAACACGCCGAACCGTGCCACCGGGGCC
GCTGCCAACGTCACGTCCGGCGCGGTGGTGGCGGGCAGCAGCGCATCTGCAGCTGCCATCTTGAATGGCGGCAGCGCACC
GATGGGCGCAACGTCCGGTAATGCCGCGGCAAATGCCCCCAATAGCGCCTCGAGCGCGGTGGCTGCTGCAGGCGACGACG
ACCTGCCGCCGCGCCCCGTGCTGCCAAGCGAAGCGTCGCGGGTCAAGATGGCGCCGGGCATGCGGCCGTTGATCGTGGCG
ATCGACCCGGGCCACGGCGGCCAGGACCCGGGCGCCATGGGTCCCACCGGCAAGCGCGAGAAGGACGTCACCCTGGCGGT
CGGCCGTGAACTGGCACGCCAGGTCAACGCCACGCCGGGCATGAAGGCCTACCTGACCCGCGATACCGACGTGTTCATTC
CGTTGCCGATGCGTGCGCAAAAAGCCCGCGCCGCCAAGGCCGACATCTTCATTTCCATCCACGCCGACGCCGCCGAAAAC
CGCAGCGCCACCGGCTCCTCGGTGTACGTACTGTCGACCAAGGGAGCCTCGTCGCAACGTGCGCGCTGGCTGGCCGACAA
GGAAAACGCGGCAGATCTAGTTGGCGGCGTGCGCCTGCAGCAGACCGAAAGCACCTTGGCCAACGTGTTGCTGGACCTGG
CTCAGAGCGGCCATATGAAGGCCTCCGAAGATGCCGCCGGCCATGTGCTTGGAGGATTGAAGCGCATCGGCAACAACCAC
AAGCCGCAACTGGAACGCGCCAACTTCGCGGTGCTGCGTACCTCCGACATGCCGGCAATGCTGGTGGAAACCGCCTTCAT
TTCCAATCCGGACGAAGAACGCCGCCTGATCGATCCGGCTTATCAGCGCAAGATCGCTGGCGCCGTGCTGGACGGCATCG
ATACCTTCTTTACCCGCCAACCGCCGCCAGGCACGTTGTTCGCAGCACGTGCGCAAGCCGAAGCCGATGCAGTCAGCACC
GTGGCCGGCGGCAGCCGCTGA

Upstream 100 bases:

>100_bases
GGCCCTTTTGCCGCCGCACGAGAAGAATGAACGCCAGGTTATGGATTATTAAGGGAAATTGCCTTGCAATTCACACAGTT
GGATGCTTGAATCCAGCGCC

Downstream 100 bases:

>100_bases
CCCGCTCGGCTATCATTCCGCACTGATTCCTTAGATGACGGCGACTGTGCGCCGCCGGATTGCCGTGCCGAGTTCTGTCT
TGCCTGTCACACCGCCGATC

Product: N-acetylmuramoyl-L-alanine amidase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MTPGIRQFCLSALTASLSLAVFAAWGGEIKGVGVSTGATGTRAEIQLAGSGGFKTLSLANPTRLVVDFPESSGMRGLKLP
SAAGLVTSVRTGQPVPGTFRVVFELATPVTPLKPQMQTLGSVSTLVIEWPGDPAPAAASAVAAAVPTAAPAPRPLNAQAE
AARATAALAASAQRASSVPPSQPSTAPPAPSVPASAMPTVTQAPVPTTVATGVPTPRPATSGAPAPTGVTGNTPNRATGA
AANVTSGAVVAGSSASAAAILNGGSAPMGATSGNAAANAPNSASSAVAAAGDDDLPPRPVLPSEASRVKMAPGMRPLIVA
IDPGHGGQDPGAMGPTGKREKDVTLAVGRELARQVNATPGMKAYLTRDTDVFIPLPMRAQKARAAKADIFISIHADAAEN
RSATGSSVYVLSTKGASSQRARWLADKENAADLVGGVRLQQTESTLANVLLDLAQSGHMKASEDAAGHVLGGLKRIGNNH
KPQLERANFAVLRTSDMPAMLVETAFISNPDEERRLIDPAYQRKIAGAVLDGIDTFFTRQPPPGTLFAARAQAEADAVST
VAGGSR

Sequences:

>Translated_566_residues
MTPGIRQFCLSALTASLSLAVFAAWGGEIKGVGVSTGATGTRAEIQLAGSGGFKTLSLANPTRLVVDFPESSGMRGLKLP
SAAGLVTSVRTGQPVPGTFRVVFELATPVTPLKPQMQTLGSVSTLVIEWPGDPAPAAASAVAAAVPTAAPAPRPLNAQAE
AARATAALAASAQRASSVPPSQPSTAPPAPSVPASAMPTVTQAPVPTTVATGVPTPRPATSGAPAPTGVTGNTPNRATGA
AANVTSGAVVAGSSASAAAILNGGSAPMGATSGNAAANAPNSASSAVAAAGDDDLPPRPVLPSEASRVKMAPGMRPLIVA
IDPGHGGQDPGAMGPTGKREKDVTLAVGRELARQVNATPGMKAYLTRDTDVFIPLPMRAQKARAAKADIFISIHADAAEN
RSATGSSVYVLSTKGASSQRARWLADKENAADLVGGVRLQQTESTLANVLLDLAQSGHMKASEDAAGHVLGGLKRIGNNH
KPQLERANFAVLRTSDMPAMLVETAFISNPDEERRLIDPAYQRKIAGAVLDGIDTFFTRQPPPGTLFAARAQAEADAVST
VAGGSR
>Mature_565_residues
TPGIRQFCLSALTASLSLAVFAAWGGEIKGVGVSTGATGTRAEIQLAGSGGFKTLSLANPTRLVVDFPESSGMRGLKLPS
AAGLVTSVRTGQPVPGTFRVVFELATPVTPLKPQMQTLGSVSTLVIEWPGDPAPAAASAVAAAVPTAAPAPRPLNAQAEA
ARATAALAASAQRASSVPPSQPSTAPPAPSVPASAMPTVTQAPVPTTVATGVPTPRPATSGAPAPTGVTGNTPNRATGAA
ANVTSGAVVAGSSASAAAILNGGSAPMGATSGNAAANAPNSASSAVAAAGDDDLPPRPVLPSEASRVKMAPGMRPLIVAI
DPGHGGQDPGAMGPTGKREKDVTLAVGRELARQVNATPGMKAYLTRDTDVFIPLPMRAQKARAAKADIFISIHADAAENR
SATGSSVYVLSTKGASSQRARWLADKENAADLVGGVRLQQTESTLANVLLDLAQSGHMKASEDAAGHVLGGLKRIGNNHK
PQLERANFAVLRTSDMPAMLVETAFISNPDEERRLIDPAYQRKIAGAVLDGIDTFFTRQPPPGTLFAARAQAEADAVSTV
AGGSR

Specific function: Cell-wall hydrolase involved in septum cleavage during cell division [H]

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

Organism=Escherichia coli, GI87082163, Length=223, Percent_Identity=45.7399103139013, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1790611, Length=230, Percent_Identity=46.5217391304348, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1788776, Length=231, Percent_Identity=41.991341991342, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021731
- InterPro:   IPR002508
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01520 Amidase_3; PF11741 AMIN [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 56982; Mature: 56851

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPGIRQFCLSALTASLSLAVFAAWGGEIKGVGVSTGATGTRAEIQLAGSGGFKTLSLAN
CCCHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEECCCCCCEEEEEEECCCCEEEEEECC
PTRLVVDFPESSGMRGLKLPSAAGLVTSVRTGQPVPGTFRVVFELATPVTPLKPQMQTLG
CEEEEEECCCCCCCCCCCCCCHHCHHHHCCCCCCCCCHHEEEEEHHCCCCCCCHHHHHCC
SVSTLVIEWPGDPAPAAASAVAAAVPTAAPAPRPLNAQAEAARATAALAASAQRASSVPP
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SQPSTAPPAPSVPASAMPTVTQAPVPTTVATGVPTPRPATSGAPAPTGVTGNTPNRATGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AANVTSGAVVAGSSASAAAILNGGSAPMGATSGNAAANAPNSASSAVAAAGDDDLPPRPV
CCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
LPSEASRVKMAPGMRPLIVAIDPGHGGQDPGAMGPTGKREKDVTLAVGRELARQVNATPG
CCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
MKAYLTRDTDVFIPLPMRAQKARAAKADIFISIHADAAENRSATGSSVYVLSTKGASSQR
CEEEEECCCEEEEECCCCHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHH
ARWLADKENAADLVGGVRLQQTESTLANVLLDLAQSGHMKASEDAAGHVLGGLKRIGNNH
HHHCCCCCCHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
KPQLERANFAVLRTSDMPAMLVETAFISNPDEERRLIDPAYQRKIAGAVLDGIDTFFTRQ
CCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
PPPGTLFAARAQAEADAVSTVAGGSR
CCCCCEEEEHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPGIRQFCLSALTASLSLAVFAAWGGEIKGVGVSTGATGTRAEIQLAGSGGFKTLSLAN
CCHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEECCCCCCEEEEEEECCCCEEEEEECC
PTRLVVDFPESSGMRGLKLPSAAGLVTSVRTGQPVPGTFRVVFELATPVTPLKPQMQTLG
CEEEEEECCCCCCCCCCCCCCHHCHHHHCCCCCCCCCHHEEEEEHHCCCCCCCHHHHHCC
SVSTLVIEWPGDPAPAAASAVAAAVPTAAPAPRPLNAQAEAARATAALAASAQRASSVPP
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SQPSTAPPAPSVPASAMPTVTQAPVPTTVATGVPTPRPATSGAPAPTGVTGNTPNRATGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AANVTSGAVVAGSSASAAAILNGGSAPMGATSGNAAANAPNSASSAVAAAGDDDLPPRPV
CCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
LPSEASRVKMAPGMRPLIVAIDPGHGGQDPGAMGPTGKREKDVTLAVGRELARQVNATPG
CCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
MKAYLTRDTDVFIPLPMRAQKARAAKADIFISIHADAAENRSATGSSVYVLSTKGASSQR
CEEEEECCCEEEEECCCCHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHH
ARWLADKENAADLVGGVRLQQTESTLANVLLDLAQSGHMKASEDAAGHVLGGLKRIGNNH
HHHCCCCCCHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
KPQLERANFAVLRTSDMPAMLVETAFISNPDEERRLIDPAYQRKIAGAVLDGIDTFFTRQ
CCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
PPPGTLFAARAQAEADAVSTVAGGSR
CCCCCEEEEHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]