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The map label for this gene is argC [H]

Identifier: 78048101

GI number: 78048101

Start: 2872888

End: 2873838

Strand: Reverse

Name: argC [H]

Synonym: XCV2545

Alternate gene names: 78048101

Gene position: 2873838-2872888 (Counterclockwise)

Preceding gene: 78048102

Following gene: 78048100

Centisome position: 55.5

GC content: 63.83

Gene sequence:

>951_bases
ATGACTGTTGAACAAAAGACCATCGGCATTGTCGGCGCCCGCGGGCATACCGGCTCGGAATTGATCAAACTGGTGGCGGC
GCATCCGCAGCTGCACTTGAGCTTCGTGTCCTCGCGCGAGCTGGCCGGGCAGCGCGTGGCCGAGCATAACGATGCCTACC
AGGGCCAGTTGCGCTACGAGAACCTGGATGCCGCCGCAGTGGCCGCCAAGGCGGCCGACGTGGTGATCCTGGCGCTGCCC
AATGGCATGGCAGAGCCCTTTGTCGCCGCGATCGACGCGGCAGCGCCACAGACGCTGGTGATCGATCTGTCGGCCGACTA
TCGCTTCGATCCGGCCTGGTACTACGGCTTGCCTGAGTTGACGCGCGGCAGTTACGCCGGGCAAAAACGCATCAGCAACC
CGGGCTGTTATGCCACCGCGATGCAGCTGACCATCGCGCCACTGCTCGACCAGCTGGCCGGGCCACCGCAGTGTTTCGGT
GTCTCCGGGTATTCGGGCGCGGGTACCACGCCTTCGGACAAGAACAATCCTGCGTTGCTCTCCAATAACGTGATGCCCTA
TGCGCTGACCAACCACATGCACGAGCGCGAGGTGTCTGCGCAGCTTGGCGTGCCGGTGGAGTTCATGCCGCATGTGGCGC
CGCATTTCCGCGGCATCACCATGACCGTCAACCTGTGGCTGCAGCAGCCGCTGACGCGCGAGCAGATCCAGGCGCGTTAT
ACGCAGCGTTATGCCGACGAGCCATTGATCGAGATCGTCGACGAGGCGCCCTGGGTGAGCCGCATCGCCGGCAAGCACGG
TGTGCAGATTGGCGGAGTAACGCTGGCGCCCGGCAACAAGCGCGTGGTGGTGGTGGCGACGCTGGACAATCTGCTCAAGG
GTGCGGCAACGCAGGCGATGCAAAACCTCAACCTTGCGCTGGGCTGGGACGAGTTGATGGCAATTCGGTGA

Upstream 100 bases:

>100_bases
ACGCCGACGGTACGCCGCGCGATACCGTGGTGTTTTCCATCATCGATACGGAATGGGCCGGGGTCAAACGCCACCTACAG
TTCCGCCTGGAAGCAAACGC

Downstream 100 bases:

>100_bases
TGCGAGTCCCTCGCAACAGCCTGCACATCCATGTGCGGGGATTTAACGAAGCGAGTCCCTCGCAACAGCCCGCGCATCCA
TGTGCGGGGATCGAAACTGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTVEQKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYENLDAAAVAAKAADVVILALP
NGMAEPFVAAIDAAAPQTLVIDLSADYRFDPAWYYGLPELTRGSYAGQKRISNPGCYATAMQLTIAPLLDQLAGPPQCFG
VSGYSGAGTTPSDKNNPALLSNNVMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELMAIR

Sequences:

>Translated_316_residues
MTVEQKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYENLDAAAVAAKAADVVILALP
NGMAEPFVAAIDAAAPQTLVIDLSADYRFDPAWYYGLPELTRGSYAGQKRISNPGCYATAMQLTIAPLLDQLAGPPQCFG
VSGYSGAGTTPSDKNNPALLSNNVMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELMAIR
>Mature_315_residues
TVEQKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYENLDAAAVAAKAADVVILALPN
GMAEPFVAAIDAAAPQTLVIDLSADYRFDPAWYYGLPELTRGSYAGQKRISNPGCYATAMQLTIAPLLDQLAGPPQCFGV
SGYSGAGTTPSDKNNPALLSNNVMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARYT
QRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELMAIR

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=340, Percent_Identity=31.4705882352941, Blast_Score=124, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320913, Length=316, Percent_Identity=47.7848101265823, Blast_Score=296, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 34081; Mature: 33950

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEQKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYE
CCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEC
NLDAAAVAAKAADVVILALPNGMAEPFVAAIDAAAPQTLVIDLSADYRFDPAWYYGLPEL
CCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCEECCCEECCCCHH
TRGSYAGQKRISNPGCYATAMQLTIAPLLDQLAGPPQCFGVSGYSGAGTTPSDKNNPALL
CCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEE
SNNVMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
ECCCCCHHHHCCHHHHHHHHHCCCCHHHHCCCCHHHCCEEEEEEEEECCCCCHHHHHHHH
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAM
HHHHCCCHHHHHHHCCCHHHHHHCCCCEEECCEEECCCCCEEEEEEEHHHHHHHHHHHHH
QNLNLALGWDELMAIR
HHCCEEECHHHHHCCC
>Mature Secondary Structure 
TVEQKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYE
CCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEC
NLDAAAVAAKAADVVILALPNGMAEPFVAAIDAAAPQTLVIDLSADYRFDPAWYYGLPEL
CCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCEECCCEECCCCHH
TRGSYAGQKRISNPGCYATAMQLTIAPLLDQLAGPPQCFGVSGYSGAGTTPSDKNNPALL
CCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEE
SNNVMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
ECCCCCHHHHCCHHHHHHHHHCCCCHHHHCCCCHHHCCEEEEEEEEECCCCCHHHHHHHH
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAM
HHHHCCCHHHHHHHCCCHHHHHHCCCCEEECCEEECCCCCEEEEEEEHHHHHHHHHHHHH
QNLNLALGWDELMAIR
HHCCEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]