Click here to switch to the map view.

The map label for this gene is ybdL [H]

Identifier: 78048077

GI number: 78048077

Start: 2845180

End: 2846346

Strand: Reverse

Name: ybdL [H]

Synonym: XCV2521

Alternate gene names: 78048077

Gene position: 2846346-2845180 (Counterclockwise)

Preceding gene: 78048089

Following gene: 78048076

Centisome position: 54.97

GC content: 65.38

Gene sequence:

>1167_bases
TTGATCCGGACAGGCACCATGCCCCTCACGACCAAGCTGCCCAAGGTGGGCACCACCATCTTCACCGTCATGTCGCAGCT
GGCGGCCGAGCACGGCGCGGTCAATCTGGGCCAGGGCTTTCCCGATTTCGCGGTGCCGCAGCGGCTGGTCGACGAACTGA
GCAAGGCCATGGCGGCCGGCCACAACCAGTATCCACCGATGACCGGCGTGGCCGCGTTGCGCCAGGCCATCGCCGGCAAG
GCACAGCGCTGCTATGGCGCGCAGGTCGATGCCGACACCGAGATCACCGTCACCAGCGGTGCCACCGAGGCGATCTTCAA
CGCCATCCACGCGGTGGTGCGCGCCGGCGAAGAGGTCATCGTGCTGGACCCGGCCTACGACTGCTACGAGCCGGCGATCG
ATCTGGCCGGCGCACGTGCCGTGCATGTGGCGCTGCACCCGCAGACCTTTGCGGTCGACTGGGCTGCGCTACGCGCCGCG
ATCACCCCCAAGACGCGCCTGTTGATGATCAACTCGCCGCACAACCCGTCCGGCGCGATGCTGTCGGCCGAGGACATGCA
GACGCTGACCGAGCTGTTGCGCGGCACCGACATCTTTTTGCTGTCCGATGAGGTCTACGAACACATCGTGTTCGATGGCC
GCCGGCACGAATCGGTGCTGCGCTGGCCGGAACTGCGCGAGCGCGCATTGGTGATTTCCAGCTTCGGCAAGACCTACCAT
TGCACCGGCTGGAAGATCGGCTACGCCATCGCACCGCCGGCGCTCACGGCCGAATTCCGCAAGGTGCACCAGTACAACAC
CTTCACCAGTTTCGGTCCGGCCCAGCACGCCTTCGCTGCGATGATCCGCGACGAGCCCGAACACGACGAGCAACTGGGCG
CGTTCTACCAAGCCAAGCGCGACCACTTCCGCGAACGGCTGCTGACCACGCGCTTGAAGCCGTTGCCTGTGCCCGGCGGC
TACTTCCAGCTGGTGGACTACTCAGCCATCAGCGATCTGCCCGATACCGAATTCGTGAAGTGGCTGACGATCGAGAAGGG
CGTGGCCGCGATTCCATTGTCGCCGTTCTACCAGAACGCGCCTGCAGGGCAGCGCCTGGCGCGGCTGTGCTTTGCCAAGA
ACGATGCGACGCTGGATGCGGCGATCGAGCGCTTGCGTAGGCTCTGA

Upstream 100 bases:

>100_bases
GGCAGCGCCGCAGGCGCCGCGATGTGTCAGGGAACGCTGTTTTGCAGCGTCCGGGCGCAACCGGCTGGCGGCTTTGCGTA
CACTCGCGGTCCCCCGTTTC

Downstream 100 bases:

>100_bases
CGAGCCGGGAATCGGGATTCGGGATTCGGGAATCGTAAGAGCGGTCGGCCGCTTTTTGATCTGAATTCGCACTGGCTCGA
TGACATAACGCCCTCATTAA

Product: putative aminotransferase

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIRTGTMPLTTKLPKVGTTIFTVMSQLAAEHGAVNLGQGFPDFAVPQRLVDELSKAMAAGHNQYPPMTGVAALRQAIAGK
AQRCYGAQVDADTEITVTSGATEAIFNAIHAVVRAGEEVIVLDPAYDCYEPAIDLAGARAVHVALHPQTFAVDWAALRAA
ITPKTRLLMINSPHNPSGAMLSAEDMQTLTELLRGTDIFLLSDEVYEHIVFDGRRHESVLRWPELRERALVISSFGKTYH
CTGWKIGYAIAPPALTAEFRKVHQYNTFTSFGPAQHAFAAMIRDEPEHDEQLGAFYQAKRDHFRERLLTTRLKPLPVPGG
YFQLVDYSAISDLPDTEFVKWLTIEKGVAAIPLSPFYQNAPAGQRLARLCFAKNDATLDAAIERLRRL

Sequences:

>Translated_388_residues
MIRTGTMPLTTKLPKVGTTIFTVMSQLAAEHGAVNLGQGFPDFAVPQRLVDELSKAMAAGHNQYPPMTGVAALRQAIAGK
AQRCYGAQVDADTEITVTSGATEAIFNAIHAVVRAGEEVIVLDPAYDCYEPAIDLAGARAVHVALHPQTFAVDWAALRAA
ITPKTRLLMINSPHNPSGAMLSAEDMQTLTELLRGTDIFLLSDEVYEHIVFDGRRHESVLRWPELRERALVISSFGKTYH
CTGWKIGYAIAPPALTAEFRKVHQYNTFTSFGPAQHAFAAMIRDEPEHDEQLGAFYQAKRDHFRERLLTTRLKPLPVPGG
YFQLVDYSAISDLPDTEFVKWLTIEKGVAAIPLSPFYQNAPAGQRLARLCFAKNDATLDAAIERLRRL
>Mature_388_residues
MIRTGTMPLTTKLPKVGTTIFTVMSQLAAEHGAVNLGQGFPDFAVPQRLVDELSKAMAAGHNQYPPMTGVAALRQAIAGK
AQRCYGAQVDADTEITVTSGATEAIFNAIHAVVRAGEEVIVLDPAYDCYEPAIDLAGARAVHVALHPQTFAVDWAALRAA
ITPKTRLLMINSPHNPSGAMLSAEDMQTLTELLRGTDIFLLSDEVYEHIVFDGRRHESVLRWPELRERALVISSFGKTYH
CTGWKIGYAIAPPALTAEFRKVHQYNTFTSFGPAQHAFAAMIRDEPEHDEQLGAFYQAKRDHFRERLLTTRLKPLPVPGG
YFQLVDYSAISDLPDTEFVKWLTIEKGVAAIPLSPFYQNAPAGQRLARLCFAKNDATLDAAIERLRRL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=404, Percent_Identity=35.3960396039604, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI56713256, Length=404, Percent_Identity=35.3960396039604, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=35.1010101010101, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=35.1010101010101, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI169881281, Length=394, Percent_Identity=31.7258883248731, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI4507369, Length=212, Percent_Identity=25.4716981132075, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=55.8201058201058, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788722, Length=301, Percent_Identity=25.5813953488372, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788627, Length=220, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1787710, Length=274, Percent_Identity=29.9270072992701, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790797, Length=330, Percent_Identity=23.9393939393939, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=35.3960396039604, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=35.3960396039604, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=32.0802005012531, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=367, Percent_Identity=20.708446866485, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=32.3907455012853, Blast_Score=200, Evalue=3e-52,
Organism=Drosophila melanogaster, GI28573069, Length=418, Percent_Identity=31.1004784688995, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24646114, Length=418, Percent_Identity=31.1004784688995, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI28573067, Length=418, Percent_Identity=31.1004784688995, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI28573065, Length=418, Percent_Identity=31.1004784688995, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI18859735, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 42769; Mature: 42769

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTGTMPLTTKLPKVGTTIFTVMSQLAAEHGAVNLGQGFPDFAVPQRLVDELSKAMAAG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHCC
HNQYPPMTGVAALRQAIAGKAQRCYGAQVDADTEITVTSGATEAIFNAIHAVVRAGEEVI
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
VLDPAYDCYEPAIDLAGARAVHVALHPQTFAVDWAALRAAITPKTRLLMINSPHNPSGAM
EECCCHHHHHHHHHHCCCEEEEEEECCCCEEEHHHHHHHHCCCCEEEEEEECCCCCCCCE
LSAEDMQTLTELLRGTDIFLLSDEVYEHIVFDGRRHESVLRWPELRERALVISSFGKTYH
EEHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCCCEEE
CTGWKIGYAIAPPALTAEFRKVHQYNTFTSFGPAQHAFAAMIRDEPEHDEQLGAFYQAKR
ECCEEECEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
DHFRERLLTTRLKPLPVPGGYFQLVDYSAISDLPDTEFVKWLTIEKGVAAIPLSPFYQNA
HHHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCHHHEEEEEECCCCEECCCCHHHCCC
PAGQRLARLCFAKNDATLDAAIERLRRL
CHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIRTGTMPLTTKLPKVGTTIFTVMSQLAAEHGAVNLGQGFPDFAVPQRLVDELSKAMAAG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHCC
HNQYPPMTGVAALRQAIAGKAQRCYGAQVDADTEITVTSGATEAIFNAIHAVVRAGEEVI
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
VLDPAYDCYEPAIDLAGARAVHVALHPQTFAVDWAALRAAITPKTRLLMINSPHNPSGAM
EECCCHHHHHHHHHHCCCEEEEEEECCCCEEEHHHHHHHHCCCCEEEEEEECCCCCCCCE
LSAEDMQTLTELLRGTDIFLLSDEVYEHIVFDGRRHESVLRWPELRERALVISSFGKTYH
EEHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCCCEEE
CTGWKIGYAIAPPALTAEFRKVHQYNTFTSFGPAQHAFAAMIRDEPEHDEQLGAFYQAKR
ECCEEECEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
DHFRERLLTTRLKPLPVPGGYFQLVDYSAISDLPDTEFVKWLTIEKGVAAIPLSPFYQNA
HHHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCHHHEEEEEECCCCEECCCCHHHCCC
PAGQRLARLCFAKNDATLDAAIERLRRL
CHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]