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The map label for this gene is mscS [C]

Identifier: 78047757

GI number: 78047757

Start: 2530166

End: 2531158

Strand: Reverse

Name: mscS [C]

Synonym: XCV2201

Alternate gene names: 78047757

Gene position: 2531158-2530166 (Counterclockwise)

Preceding gene: 78047758

Following gene: 78047753

Centisome position: 48.88

GC content: 62.84

Gene sequence:

>993_bases
ATGGGACTGATGGGTGCGATGTGGGCAGCAGCTGCAGGAGCAGCTGCTGCAAGACCGGTTGCTGCAGCAGGAGCGGCAGC
CGCGAAGCCCGCCGCGACCAGCGAGCCGGCATTCAACTGGGCCGCCATTCCGTGGGCGCAGTACGCGGTCAACTGGGGAG
TGGCACTGCTGATCGTCGTGGTCGGCATGTGGCTGGCCCGGCAACTCAGCCAGTGGTTGCACCGCGCGCTCACCCGCGCA
CGCGTCGAGATCACGCTGACCAATTTCCTGCGCAACGTGATGTACGCGTTGTTGCTGGTGCTGGTCTTCGTCAGCGCATT
GAGTCAGATCGGTGTGCCACCGACCTCACTGATCGCAGTGCTCGGCGCAGCAGGCCTGGCGGTCGGCCTTGCCCTGAAGG
ATTCGCTGTCCAACATCGCCGCAGGCGTGATGCTGATCGTGCTGCGGCCGATGCGCGATGGCGACCACGTGTTGATCGCC
GGGCAGGAAGGCATCGTCGACGAGATCCGGATCTTCCAGACCCGGATCCGTTCGTTCGACGAACGCATGATCACCCTGCC
AAACAGCACGATTACCACCGCCCCCATCGTCAACTACAGCACCCTGCCCAACCGCCGCCTGGAAGTGACGGTCGGCGTGG
GCTACCAAGACGATCTGAAGAAGGCGCAGCAGCTGTTGCTGCAGATCGCCAAGGACAACCCGAACATCCTGGAGTCGCCT
GCACCATTCGTGCAGGTGACCAACCTGGGCGAGAGTACGGTGGACCTGATGTTGTTCGCGTATGCGACCAACGGCAATTT
CGGCGCTGCCAAGAGCACCACACTGGAGCAGATCCGCAACCAGTTGCTGGAAAACGGACTCAACATCCCCTACCCGCAGC
GCGACCTGCACGTGTATCACCACGATGCCGATGGCAAGCCGATCTCCGACCTGTTGCTGAAAGGCATCGCAGACGATGGC
GACCTGAGCAAGGGGCCTTCGTTGGCGCGCTGA

Upstream 100 bases:

>100_bases
CCGAGTGGCTGATGCAGGAAGGAATCGAATCGGTGTCGTTGAATCCCGACACCGTGGTCGACACCTGGCTGCGTCTGGCC
AAGCTCAAGAGCGAGGGCTG

Downstream 100 bases:

>100_bases
CGTACACAATGGCGTGATGGAAAGGCAGAAAAGGCCGCATCGAACGATGCGGCCTTTTTTGTTGATGCCTTTCTTGTCGG
ATGCTTTTGTTGGATGGGTC

Product: small-conductance mechanosensitive channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MGLMGAMWAAAAGAAAARPVAAAGAAAAKPAATSEPAFNWAAIPWAQYAVNWGVALLIVVVGMWLARQLSQWLHRALTRA
RVEITLTNFLRNVMYALLLVLVFVSALSQIGVPPTSLIAVLGAAGLAVGLALKDSLSNIAAGVMLIVLRPMRDGDHVLIA
GQEGIVDEIRIFQTRIRSFDERMITLPNSTITTAPIVNYSTLPNRRLEVTVGVGYQDDLKKAQQLLLQIAKDNPNILESP
APFVQVTNLGESTVDLMLFAYATNGNFGAAKSTTLEQIRNQLLENGLNIPYPQRDLHVYHHDADGKPISDLLLKGIADDG
DLSKGPSLAR

Sequences:

>Translated_330_residues
MGLMGAMWAAAAGAAAARPVAAAGAAAAKPAATSEPAFNWAAIPWAQYAVNWGVALLIVVVGMWLARQLSQWLHRALTRA
RVEITLTNFLRNVMYALLLVLVFVSALSQIGVPPTSLIAVLGAAGLAVGLALKDSLSNIAAGVMLIVLRPMRDGDHVLIA
GQEGIVDEIRIFQTRIRSFDERMITLPNSTITTAPIVNYSTLPNRRLEVTVGVGYQDDLKKAQQLLLQIAKDNPNILESP
APFVQVTNLGESTVDLMLFAYATNGNFGAAKSTTLEQIRNQLLENGLNIPYPQRDLHVYHHDADGKPISDLLLKGIADDG
DLSKGPSLAR
>Mature_329_residues
GLMGAMWAAAAGAAAARPVAAAGAAAAKPAATSEPAFNWAAIPWAQYAVNWGVALLIVVVGMWLARQLSQWLHRALTRAR
VEITLTNFLRNVMYALLLVLVFVSALSQIGVPPTSLIAVLGAAGLAVGLALKDSLSNIAAGVMLIVLRPMRDGDHVLIAG
QEGIVDEIRIFQTRIRSFDERMITLPNSTITTAPIVNYSTLPNRRLEVTVGVGYQDDLKKAQQLLLQIAKDNPNILESPA
PFVQVTNLGESTVDLMLFAYATNGNFGAAKSTTLEQIRNQLLENGLNIPYPQRDLHVYHHDADGKPISDLLLKGIADDGD
LSKGPSLAR

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=258, Percent_Identity=36.046511627907, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1786670, Length=241, Percent_Identity=28.6307053941909, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787591, Length=251, Percent_Identity=25.0996015936255, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI2367355, Length=242, Percent_Identity=23.5537190082645, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 35360; Mature: 35228

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS01246 UPF0003

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLMGAMWAAAAGAAAARPVAAAGAAAAKPAATSEPAFNWAAIPWAQYAVNWGVALLIVV
CCCHHHHHHHHHCHHHHCCHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHH
VGMWLARQLSQWLHRALTRARVEITLTNFLRNVMYALLLVLVFVSALSQIGVPPTSLIAV
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGAAGLAVGLALKDSLSNIAAGVMLIVLRPMRDGDHVLIAGQEGIVDEIRIFQTRIRSFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
ERMITLPNSTITTAPIVNYSTLPNRRLEVTVGVGYQDDLKKAQQLLLQIAKDNPNILESP
HHEEECCCCCCCCCCCEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
APFVQVTNLGESTVDLMLFAYATNGNFGAAKSTTLEQIRNQLLENGLNIPYPQRDLHVYH
CCEEEEECCCCHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
HDADGKPISDLLLKGIADDGDLSKGPSLAR
ECCCCCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLMGAMWAAAAGAAAARPVAAAGAAAAKPAATSEPAFNWAAIPWAQYAVNWGVALLIVV
CCHHHHHHHHHCHHHHCCHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHH
VGMWLARQLSQWLHRALTRARVEITLTNFLRNVMYALLLVLVFVSALSQIGVPPTSLIAV
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGAAGLAVGLALKDSLSNIAAGVMLIVLRPMRDGDHVLIAGQEGIVDEIRIFQTRIRSFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
ERMITLPNSTITTAPIVNYSTLPNRRLEVTVGVGYQDDLKKAQQLLLQIAKDNPNILESP
HHEEECCCCCCCCCCCEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
APFVQVTNLGESTVDLMLFAYATNGNFGAAKSTTLEQIRNQLLENGLNIPYPQRDLHVYH
CCEEEEECCCCHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
HDADGKPISDLLLKGIADDGDLSKGPSLAR
ECCCCCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]