Click here to switch to the map view.

The map label for this gene is trxB1 [H]

Identifier: 78047611

GI number: 78047611

Start: 2338678

End: 2339646

Strand: Reverse

Name: trxB1 [H]

Synonym: XCV2055

Alternate gene names: 78047611

Gene position: 2339646-2338678 (Counterclockwise)

Preceding gene: 78047615

Following gene: 78047610

Centisome position: 45.18

GC content: 65.94

Gene sequence:

>969_bases
ATGAGCGCCTTTTCTGCCAGCCCCGCCAAGCACTCCCGCCTGTTGATCCTGGGCTCCGGCCCGGCCGGCTGGACCGCCGC
GGTCTACGCCGCCCGCGCCAATCTCAAGCCGGTGGTCATCACCGGGCTGCAGCAAGGCGGCCAACTGATGACCACCACCG
AGGTGGACAACTGGCCGGGCGACCCCCACGGCCTGATGGGTCCGGACCTGATGAGCCGCATGCAGGCGCATGCCGAGCGC
TTCGAGACCGAGGTCATCTTCGACCATATCCACACGGCAGATCTGTCGCAGCGTCCGTTCCGGCTGATCGGCGACGGGGC
CGAGTACACCTGCGACGCGCTCATCATCGCCACCGGCGCTACCGCCAAGTACCTGGGCATCCCCACCGAAGAAGCCTTCA
AGGGGCGTGGCGTCTCCGCCTGCGCCACCTGCGACGGCTTCTTCTACAAGGACCAGGACGTGGTGGTGGTCGGCGGCGGC
AACACCGCGGTCGAAGAGGCGCTGTACCTGTCCAACATTGCCCGCAAGGTCTACCTGGTGCATCGCCGCGATACGCTGCG
CGCAGAGAAAATCATGCAGGACAAGCTGTTCGCCAAAGTGGCCGCCGGCAAGATCGAGACCGTCTGGCACCATGCCATCG
ACGAGGTACTGGGCAACGATGCCGGGGTTACCGGCGTCCGAGTGAAGTCCACCATCGACGGCAGCACCCGCGACATCGAT
GCGCATGGTTTCTTCGTGGCGATCGGCCATCACCCGAACACGCAGTTGTTCGATGGCCAGTTGGCAATGAACAACGGCTA
CCTGGAAATCCGCTCCGGCCTGAACGGCGCCGCGACCGAGACCTCGGTGGCCGGCGTGTTCGCCGCCGGCGACGTGGCCG
ACCAGCATTACCGCCAGGCCATCACCTCGGCCGGCTTCGGCTGCATGGCCGCGCTGGATGCCGAGCGTTATCTCGACAAG
AGCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCCGCCTTGATTCACCGGGTGGGGACCGCCACTCTATGCCGCCACGGGGGCGCGAATTACTTCGCCTGCCCTACCAA
TTCCTAGATCGCGAGTATAC

Downstream 100 bases:

>100_bases
GATGGCGCCTGATTGCCGGCCGCGCCACGCGGCCAGCATCGCCAAGGGGCTGCCCGCATGGGCATAACCGCACGCTGGTG
TCGCCAGCTGGACGAGTTGC

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSAFSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPGDPHGLMGPDLMSRMQAHAER
FETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGATAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGG
NTAVEEALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQAITSAGFGCMAALDAERYLDK
SA

Sequences:

>Translated_322_residues
MSAFSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPGDPHGLMGPDLMSRMQAHAER
FETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGATAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGG
NTAVEEALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQAITSAGFGCMAALDAERYLDK
SA
>Mature_321_residues
SAFSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPGDPHGLMGPDLMSRMQAHAERF
ETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGATAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGGN
TAVEEALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDIDA
HGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQAITSAGFGCMAALDAERYLDKS
A

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=67.8456591639871, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI87081763, Length=323, Percent_Identity=31.8885448916409, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=43.75, Blast_Score=263, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=42.5, Blast_Score=252, Evalue=6e-68,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34400; Mature: 34269

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPG
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCC
DPHGLMGPDLMSRMQAHAERFETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEECC
TAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGGNTAVEEALYLSNIARKVYLV
CEEEECCCCHHHHCCCCCEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEE
HRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
ECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEC
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQA
CCEEEEEECCCCCCEEECCEEEECCCEEEEECCCCCCCCCHHHHEEEEECCHHHHHHHHH
ITSAGFGCMAALDAERYLDKSA
HHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAFSASPAKHSRLLILGSGPAGWTAAVYAARANLKPVVITGLQQGGQLMTTTEVDNWPG
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCC
DPHGLMGPDLMSRMQAHAERFETEVIFDHIHTADLSQRPFRLIGDGAEYTCDALIIATGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEECC
TAKYLGIPTEEAFKGRGVSACATCDGFFYKDQDVVVVGGGNTAVEEALYLSNIARKVYLV
CEEEECCCCHHHHCCCCCEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEE
HRRDTLRAEKIMQDKLFAKVAAGKIETVWHHAIDEVLGNDAGVTGVRVKSTIDGSTRDID
ECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEC
AHGFFVAIGHHPNTQLFDGQLAMNNGYLEIRSGLNGAATETSVAGVFAAGDVADQHYRQA
CCEEEEEECCCCCCEEECCEEEECCCEEEEECCCCCCCCCHHHHEEEEECCHHHHHHHHH
ITSAGFGCMAALDAERYLDKSA
HHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]