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The map label for this gene is fabH [C]

Identifier: 78047567

GI number: 78047567

Start: 2292929

End: 2293969

Strand: Reverse

Name: fabH [C]

Synonym: XCV2011

Alternate gene names: 78047567

Gene position: 2293969-2292929 (Counterclockwise)

Preceding gene: 78047568

Following gene: 78047566

Centisome position: 44.3

GC content: 62.25

Gene sequence:

>1041_bases
ATGCCGACCTCCACGCTGCATAACGTCCGCTTTGCCGGCATGGCGACATGCGTGCCAAAGCGTGTAGTGTCTAATCTCAC
CGATTGCCGTCCGCAGATTCGCTCCGAACGCGAGCGTCTGGTGCGCAACATCGGCATCGAGACCCGGCGGATGGCGTCGG
AATGGCAGTGTTTTTCCGACCTGGCCTTCGATGCGACCGAGGTGCTGCTGGAAAAGCTGCAGTGGAAGCGCGAGGAGATC
GATGCATTGATCGTGGTGACCCAGTCGCCGGATTACCCGATTCCGGCCACCGCCATCATCCTGCAGGACAGGCTGGGGCT
GTCGCATGCCACGGTCGCCTTCGACGTCAACCTGGGCTGCTCGGCCTACCCGTTTGGCATCAACCTGCTCGGCTCGATGA
TCGCCGCCGGTGGCGTCAAGAAGGGCCTGCTGCTGGTCGGCGACCGCAGCGCCAACCTTGAAGACCCGATCTTCTCCGAC
TCCGGCACCGCCACGGCGCTGGAGTTCAGCGCCGACGCGCCGCCGATGTATTTCGACCTCAACAGCGATGGCAGTGGCTA
CAAGGCCATCATCCTGCCGGTGGGTGGTCACCGCGAACCGGTCGGCATCCAGCACTTGGTGCCGTATCGCGACGAGGCGG
ATGGTGCCTGGAAGCGTGGCGTGGACCTGATCCTGGACGGCGTGGCAGTGCTGAGCTTCTCTACCCAGCGCATTCCACCT
GCCGTGCAGAAACTGCTTGAGTACACCGGCGTGGCCAAGGAAGACATCGATTACTTCGTGTTTCACCAGGCCAACCGCAT
GATCAACGAGACAATTCGCAAAAAGCTCGGCCTGCCGGTGGAAAAGGTGCCTTCGACACTGCGCGACTTCGGCAACACCA
GCGGCGCCTCGCTGCCGGTGACCATGACCGCGCGCATTAATAAGGAACTGGAATCGGGCCGCAAGCGCGTGCTGCTATGC
GGCTTCGGCATCGGGCTGTCGTGGGGCACCTGCCTGGTGGATATCGAGGGCGCGGTGTTTCCTGATTTGATCGAGTCATG
A

Upstream 100 bases:

>100_bases
TGATGTTCGACATGGAATACGGCAAGACCATCACCGGCGAAGATCTCGCCGTTGCCATCACCGTCGGCGATCTTTACAAA
CTGACCGAGGCGTAAGCACC

Downstream 100 bases:

>100_bases
CGGCCACACCTGCAGCAACCACTGATGCGTTCGGGCTGCAAAACAAGACCGTTCTAGTGACCGGCGCGTCGTCGGGCATT
GGCGCTGCAGTCGCCACGTT

Product: 3-oxoacyl-[acyl-carrier protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MPTSTLHNVRFAGMATCVPKRVVSNLTDCRPQIRSERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLEKLQWKREEI
DALIVVTQSPDYPIPATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSD
SGTATALEFSADAPPMYFDLNSDGSGYKAIILPVGGHREPVGIQHLVPYRDEADGAWKRGVDLILDGVAVLSFSTQRIPP
AVQKLLEYTGVAKEDIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNTSGASLPVTMTARINKELESGRKRVLLC
GFGIGLSWGTCLVDIEGAVFPDLIES

Sequences:

>Translated_346_residues
MPTSTLHNVRFAGMATCVPKRVVSNLTDCRPQIRSERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLEKLQWKREEI
DALIVVTQSPDYPIPATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSD
SGTATALEFSADAPPMYFDLNSDGSGYKAIILPVGGHREPVGIQHLVPYRDEADGAWKRGVDLILDGVAVLSFSTQRIPP
AVQKLLEYTGVAKEDIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNTSGASLPVTMTARINKELESGRKRVLLC
GFGIGLSWGTCLVDIEGAVFPDLIES
>Mature_345_residues
PTSTLHNVRFAGMATCVPKRVVSNLTDCRPQIRSERERLVRNIGIETRRMASEWQCFSDLAFDATEVLLEKLQWKREEID
ALIVVTQSPDYPIPATAIILQDRLGLSHATVAFDVNLGCSAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSDS
GTATALEFSADAPPMYFDLNSDGSGYKAIILPVGGHREPVGIQHLVPYRDEADGAWKRGVDLILDGVAVLSFSTQRIPPA
VQKLLEYTGVAKEDIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNTSGASLPVTMTARINKELESGRKRVLLCG
FGIGLSWGTCLVDIEGAVFPDLIES

Specific function: May catalyze the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=335, Percent_Identity=26.2686567164179, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37822; Mature: 37691

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSTLHNVRFAGMATCVPKRVVSNLTDCRPQIRSERERLVRNIGIETRRMASEWQCFSD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAFDATEVLLEKLQWKREEIDALIVVTQSPDYPIPATAIILQDRLGLSHATVAFDVNLGC
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEHHCCCCEEEEEEEECCCC
SAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSDSGTATALEFSADAPPMYFDL
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEE
NSDGSGYKAIILPVGGHREPVGIQHLVPYRDEADGAWKRGVDLILDGVAVLSFSTQRIPP
CCCCCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCHHHHCHHHHHHHHHHEECCCCCCCH
AVQKLLEYTGVAKEDIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNTSGASLPV
HHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEE
TMTARINKELESGRKRVLLCGFGIGLSWGTCLVDIEGAVFPDLIES
EEHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHCC
>Mature Secondary Structure 
PTSTLHNVRFAGMATCVPKRVVSNLTDCRPQIRSERERLVRNIGIETRRMASEWQCFSD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAFDATEVLLEKLQWKREEIDALIVVTQSPDYPIPATAIILQDRLGLSHATVAFDVNLGC
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEHHCCCCEEEEEEEECCCC
SAYPFGINLLGSMIAAGGVKKGLLLVGDRSANLEDPIFSDSGTATALEFSADAPPMYFDL
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEE
NSDGSGYKAIILPVGGHREPVGIQHLVPYRDEADGAWKRGVDLILDGVAVLSFSTQRIPP
CCCCCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCHHHHCHHHHHHHHHHEECCCCCCCH
AVQKLLEYTGVAKEDIDYFVFHQANRMINETIRKKLGLPVEKVPSTLRDFGNTSGASLPV
HHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEE
TMTARINKELESGRKRVLLCGFGIGLSWGTCLVDIEGAVFPDLIES
EEHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]