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The map label for this gene is lpxD [C]

Identifier: 78047562

GI number: 78047562

Start: 2288952

End: 2289566

Strand: Reverse

Name: lpxD [C]

Synonym: XCV2006

Alternate gene names: 78047562

Gene position: 2289566-2288952 (Counterclockwise)

Preceding gene: 78047563

Following gene: 78047561

Centisome position: 44.21

GC content: 61.79

Gene sequence:

>615_bases
TTGACCTCACTCATCCTGCTGGGTCAGGACGATGCGCTAACGCAGGCGGTACGCGCGGCAAACGCATGCGGATTGGTGCA
CACCGTGATCGAACTGAAATCGGCCGACCGTCACAACTTCGAGCTGGACGACATCTTCGCGCGCTTCCCGACGGCAGACA
GCGAAGTTTTTGTCGCGCTGGACGCACGGGCGGTGAACTACGCACGCCACAAGCTGGTCGCGCAGCTGCGGCTTGCCGGC
TATCGATTGGCGAACCTGATTTCGCCAACGGCCATAGTCGATGACGATGTGCGTTTGGCAGGCAATGTCTACATCGGACC
CGGGTGCAACGTTGCTCCTGGCACGCGCATCGGCGTCGGTTGTTGGCTCGATCGCCAGGTCGTGATCGAGTCCGATGTCC
GCCTGGGTGCCTGCACAACTCTACATGCAGGCGTCTCGATTGGGCGAGCTGTGGACATCGGGCAAGGCAGTACACTGGGC
AGCGGCAGCATCGCAGGCGCTGGCACGAAAATCGGCCGTCATTGCGAGTGGCTGCTGCCCGGCGTATTGCCCATCACCCT
CCCGGACCGTTCCTTCTACGATGCGCTGATGCCCCAGGGAGCACGCATTTTGTGA

Upstream 100 bases:

>100_bases
GTTTCGGACCGCACTCCGACCACATCACGCACGGCGATTACGAGATTCAACTGGTGCGCCAGCATCGTTGGTACCGCGGC
GCGGTGCTGGAGGAAACGCA

Downstream 100 bases:

>100_bases
TTGACCTAATCATTCAAACAGCCCAACAAACTTTGCCTTTCCCGAGAACATGTAATGACGCTGGATGAGTACCAACGGAT
GAGCATCAATCCCGACGGGG

Product: hypothetical protein

Products: UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine; [Acyl-Carrier Protein]. [C]

Alternate protein names: None

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTSLILLGQDDALTQAVRAANACGLVHTVIELKSADRHNFELDDIFARFPTADSEVFVALDARAVNYARHKLVAQLRLAG
YRLANLISPTAIVDDDVRLAGNVYIGPGCNVAPGTRIGVGCWLDRQVVIESDVRLGACTTLHAGVSIGRAVDIGQGSTLG
SGSIAGAGTKIGRHCEWLLPGVLPITLPDRSFYDALMPQGARIL

Sequences:

>Translated_204_residues
MTSLILLGQDDALTQAVRAANACGLVHTVIELKSADRHNFELDDIFARFPTADSEVFVALDARAVNYARHKLVAQLRLAG
YRLANLISPTAIVDDDVRLAGNVYIGPGCNVAPGTRIGVGCWLDRQVVIESDVRLGACTTLHAGVSIGRAVDIGQGSTLG
SGSIAGAGTKIGRHCEWLLPGVLPITLPDRSFYDALMPQGARIL
>Mature_203_residues
TSLILLGQDDALTQAVRAANACGLVHTVIELKSADRHNFELDDIFARFPTADSEVFVALDARAVNYARHKLVAQLRLAGY
RLANLISPTAIVDDDVRLAGNVYIGPGCNVAPGTRIGVGCWLDRQVVIESDVRLGACTTLHAGVSIGRAVDIGQGSTLGS
GSIAGAGTKIGRHCEWLLPGVLPITLPDRSFYDALMPQGARIL

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 21615; Mature: 21484

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLILLGQDDALTQAVRAANACGLVHTVIELKSADRHNFELDDIFARFPTADSEVFVAL
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEE
DARAVNYARHKLVAQLRLAGYRLANLISPTAIVDDDVRLAGNVYIGPGCNVAPGTRIGVG
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECEEEECCCCCCCCCCEEEEE
CWLDRQVVIESDVRLGACTTLHAGVSIGRAVDIGQGSTLGSGSIAGAGTKIGRHCEWLLP
EEECCEEEEECCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHEECC
GVLPITLPDRSFYDALMPQGARIL
CEEEEEECCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSLILLGQDDALTQAVRAANACGLVHTVIELKSADRHNFELDDIFARFPTADSEVFVAL
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEE
DARAVNYARHKLVAQLRLAGYRLANLISPTAIVDDDVRLAGNVYIGPGCNVAPGTRIGVG
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECEEEECCCCCCCCCCEEEEE
CWLDRQVVIESDVRLGACTTLHAGVSIGRAVDIGQGSTLGSGSIAGAGTKIGRHCEWLLP
EEECCEEEEECCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHEECC
GVLPITLPDRSFYDALMPQGARIL
CEEEEEECCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine; (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] [C]

Specific reaction: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine + (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] = UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine + [Acyl-Carrier Protein]. [C]

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA