Click here to switch to the map view.

The map label for this gene is ccmE1 [H]

Identifier: 78047269

GI number: 78047269

Start: 1933671

End: 1934141

Strand: Reverse

Name: ccmE1 [H]

Synonym: XCV1713

Alternate gene names: 78047269

Gene position: 1934141-1933671 (Counterclockwise)

Preceding gene: 78047270

Following gene: 78047268

Centisome position: 37.35

GC content: 62.42

Gene sequence:

>471_bases
ATGAACGCCACGCGTAGACAACGTCTGTGGTGGGTGATCTGTGTACTCACCGCCGCCGCGTTGGCCGTCACGCTCATCGT
GTTCGCTTTGCAGCGGAACATGAGCTACCTGTTCACCCCAAGCCAGGTCAGCGCGGGGGAAGCCGCCGGCTACCAGCAAT
TCCGGCTCGGTGGCATGGTCAAGGCCGGTTCGATCCAGCGTGCAGGTGATTCGCTGAAAGTCAGCTTCACCGTCATCGAT
AAAAACGCGGCCACCCAGGTGGAGTACACCGGCATTCTTCCGGATCTGTTTCGCGACAACCAGTCGGTCATCGCCAACGG
GCGCATGCAGGGCGGGCGCTTCGTCGCCAACGAAGTGCTGGCCAAGCACGACGAGACCTACATGCCGAAAGAGCTGAAGG
ACGCCATGGCCGAAGGCCATGCCGGAAAACCAATCCCCGCCACCGCCACGCCGCTGACCGCGCCGCGTTGA

Upstream 100 bases:

>100_bases
GTCGCCGCCGCTTGCCGCGTGAACTGCGCGGCCAGTTGCAGCGGCAGGTGCCGCGTCGTGCACGCGATCAACCGGCACCG
GCACTGGAGCGCGACGCGCC

Downstream 100 bases:

>100_bases
TGCGCTTCCGGTCGCTGCCACGCACCTCATGACTTCCCTTCCGTTTCGCCTTGCGATCCGCCCATGACGCCTGAACTTGG
CCAGATCGCGCTGATCCTGG

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E 1; Heme chaperone CcmE 1 [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MNATRRQRLWWVICVLTAAALAVTLIVFALQRNMSYLFTPSQVSAGEAAGYQQFRLGGMVKAGSIQRAGDSLKVSFTVID
KNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAEGHAGKPIPATATPLTAPR

Sequences:

>Translated_156_residues
MNATRRQRLWWVICVLTAAALAVTLIVFALQRNMSYLFTPSQVSAGEAAGYQQFRLGGMVKAGSIQRAGDSLKVSFTVID
KNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAEGHAGKPIPATATPLTAPR
>Mature_156_residues
MNATRRQRLWWVICVLTAAALAVTLIVFALQRNMSYLFTPSQVSAGEAAGYQQFRLGGMVKAGSIQRAGDSLKVSFTVID
KNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAEGHAGKPIPATATPLTAPR

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=147, Percent_Identity=42.8571428571429, Blast_Score=130, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 16956; Mature: 16956

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATRRQRLWWVICVLTAAALAVTLIVFALQRNMSYLFTPSQVSAGEAAGYQQFRLGGMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHCCEE
KAGSIQRAGDSLKVSFTVIDKNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVL
ECCCCCCCCCCEEEEEEEEECCCCCEEEECCCCHHHHCCCCCEEECCCCCCCCHHHHHHH
AKHDETYMPKELKDAMAEGHAGKPIPATATPLTAPR
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNATRRQRLWWVICVLTAAALAVTLIVFALQRNMSYLFTPSQVSAGEAAGYQQFRLGGMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHCCEE
KAGSIQRAGDSLKVSFTVIDKNAATQVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVL
ECCCCCCCCCCEEEEEEEEECCCCCEEEECCCCHHHHCCCCCEEECCCCCCCCHHHHHHH
AKHDETYMPKELKDAMAEGHAGKPIPATATPLTAPR
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]