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The map label for this gene is ccmF1 [H]

Identifier: 78047268

GI number: 78047268

Start: 1931619

End: 1933607

Strand: Reverse

Name: ccmF1 [H]

Synonym: XCV1712

Alternate gene names: 78047268

Gene position: 1933607-1931619 (Counterclockwise)

Preceding gene: 78047269

Following gene: 78047267

Centisome position: 37.34

GC content: 66.06

Gene sequence:

>1989_bases
ATGACGCCTGAACTTGGCCAGATCGCGCTGATCCTGGCACTGCTGTTATCGCTCGCCCAGGGTGTAGTGCCCTTGATCGG
TGCGTGGCGCGGCAACACCGCGTTGATGGGTGTCGCGCGGCCTGCGGCGGTGGGCCAGGCGGTGTTCGTGTGGATGGCGT
TCGGCCTGCTCGCCTGGTCGTTGTTGTCGCTGGATTTTTCGGTGGGCTACGTCGCCGCCAACGCCAACATTGCCCTGCCC
TGGTACTACCGCGTTGCGGCGGTGTGGGGCGCGCACGAAGGCTCGTTGCTGTTGTGGATCGCCATCCTCGCCACCTGGAC
GGTGCTGCTGGCCGCCTTCAGCCGGCACCTGCCGCAACATTTTGCCGCCCGCGTGCTGGCGATCCTGGGGCTGATTTCGG
TGGGCTTTCTGGCCTTCATCCTGCTGACCTCCAATCCGTTCGGGCGGCTGTCGCCGATTCCGCTGGATGGCAATGAACTC
AATCCGGTGTTGCAGGACCCCGGCATGACCTTCCACCCGCCGGTGTTGTACACCGGCTATGTCGGGTTTTCGGTAGCCTT
CGCATTCGCAGTGGCGGCATTGCTCGGCGGCGAACTGGAACAGGCCTGGGTGCGCTGGGCACGGCCGTGGACCAATGTGG
CCTGGGCCTGCCTCACCGCCGGCATCGTCGCCGGCAGCTGGTGGGCCTATGCGGAACTGGGCTGGGGCGGCTGGTGGTTC
TGGGACCCGGTGGAAAACGCCAGTTTCATGCCCTGGCTGGTCGGCACTGCGTTGATCCACTCCCAGGCGGTCACCGAAAA
ACGCGGCAGCCTGCGCGCGTGGACCATCCTGCTGTCGATCCTGGCGTTTTCGCTCTCGTTGCTGGGCACCTTCCTGGTGC
GCTCGGGCGTGCTGACCTCGGTGCACGCGTTTGCGGCCGATCCGCGCCGTGGCCTGTACATCCTCATTTTTCTGGTTGCC
GTCGTCGGCGGCTCGTTGCTGTTGTATGCACTGCGCGCGCCCAAGATCGCCAGCGGCAAACCCTTTGCCGCCGCCTCGCG
CGAAACCGGCATTCTCATCGGCAACCTACTGCTCACCGTGGCCGCGGCCATGGTGTTGCTGGGCACCTTGTTCCCGCTGA
TCGCCGACGCGTTTGCGCTGGGCAAGGTCTCGGTCGGGCCGCCCTACTTCGGCCTGCTGTTTCCGTTGTTGATGTTGCCG
GTGGTGCTGTTGCTGCCGTTCGGCCCCTACCTGCGCTGGGGCAAGGCCGAAGCCGCACCGTTGAAAGCACTCGGCACACG
CGCAGGCATCGCCGCGATTGCCTGCGCCCTGGTCGGCAGTGTGTTTGCCGATGGCCAGGCCAAGGCGATCGCCGGCATGG
GTGTGGCCGCATGGGTGGCTGCGGGCACCGCGTTGTACGTGGTCAAACGCTGGCGCGACATGCCGCGCGGGCGGCGCTTC
CCGGCGGAAATGGCCGGCATGCTGATCGCGCATGCGGGCGTGGCGGTGTTCGTTGCCGGCGTGCTGGTCTCCGAAAGCCT
GTCGGTGGAACGCGATGTACGGCTGTCGCCCGGCCAGAGCGCGCAGGTCGCCGGCTACAGCTTCCGCTTCGATGGCGTGC
AGTTGGTGGATGGGCCGAACTGGAAGGCCGAACAAGGCAGCGTGCAGGTCAGCCGCAACGGCCAGGTGGTCGCGCAACTG
CATCCGCAAAAACGCCTGTACAGCAGCGAGCGGATCCAGACCGAATCGGCCATCGATCCCGGCATCACCCGCGACCTGTA
TGTGGCGCTGGGCGAGCCCTTGGACGATGAGCACATCGAAAACGACTGGACGCTGCGCCTGTACTACAAGCCCTTCATTC
GCTGGATCTGGGCCGGTGGCCTGCTGATGATGCTCGGCGGCTTCGTCAGCGCCTGCGCACGCCGCTTTCGTGCACCGGTG
ACTGCACACCCCTTGGCCGCTTCTCCGGCGCAACCAGCGCTCGTCATCGCACAGGAATCGCACCCGTGA

Upstream 100 bases:

>100_bases
CCCCGCCACCGCCACGCCGCTGACCGCGCCGCGTTGATGCGCTTCCGGTCGCTGCCACGCACCTCATGACTTCCCTTCCG
TTTCGCCTTGCGATCCGCCC

Downstream 100 bases:

>100_bases
ATCGTCTGCTGCCCTTGCTGGGCTTCGTATTGCTGGCGGCGCTGTTCGGCGTCGGCATCCTGCGGACCATGCAGCACAAT
CCGCGCGACGTACCGTCGCC

Product: C-type cytochrome biogenesis membrane protein CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MTPELGQIALILALLLSLAQGVVPLIGAWRGNTALMGVARPAAVGQAVFVWMAFGLLAWSLLSLDFSVGYVAANANIALP
WYYRVAAVWGAHEGSLLLWIAILATWTVLLAAFSRHLPQHFAARVLAILGLISVGFLAFILLTSNPFGRLSPIPLDGNEL
NPVLQDPGMTFHPPVLYTGYVGFSVAFAFAVAALLGGELEQAWVRWARPWTNVAWACLTAGIVAGSWWAYAELGWGGWWF
WDPVENASFMPWLVGTALIHSQAVTEKRGSLRAWTILLSILAFSLSLLGTFLVRSGVLTSVHAFAADPRRGLYILIFLVA
VVGGSLLLYALRAPKIASGKPFAAASRETGILIGNLLLTVAAAMVLLGTLFPLIADAFALGKVSVGPPYFGLLFPLLMLP
VVLLLPFGPYLRWGKAEAAPLKALGTRAGIAAIACALVGSVFADGQAKAIAGMGVAAWVAAGTALYVVKRWRDMPRGRRF
PAEMAGMLIAHAGVAVFVAGVLVSESLSVERDVRLSPGQSAQVAGYSFRFDGVQLVDGPNWKAEQGSVQVSRNGQVVAQL
HPQKRLYSSERIQTESAIDPGITRDLYVALGEPLDDEHIENDWTLRLYYKPFIRWIWAGGLLMMLGGFVSACARRFRAPV
TAHPLAASPAQPALVIAQESHP

Sequences:

>Translated_662_residues
MTPELGQIALILALLLSLAQGVVPLIGAWRGNTALMGVARPAAVGQAVFVWMAFGLLAWSLLSLDFSVGYVAANANIALP
WYYRVAAVWGAHEGSLLLWIAILATWTVLLAAFSRHLPQHFAARVLAILGLISVGFLAFILLTSNPFGRLSPIPLDGNEL
NPVLQDPGMTFHPPVLYTGYVGFSVAFAFAVAALLGGELEQAWVRWARPWTNVAWACLTAGIVAGSWWAYAELGWGGWWF
WDPVENASFMPWLVGTALIHSQAVTEKRGSLRAWTILLSILAFSLSLLGTFLVRSGVLTSVHAFAADPRRGLYILIFLVA
VVGGSLLLYALRAPKIASGKPFAAASRETGILIGNLLLTVAAAMVLLGTLFPLIADAFALGKVSVGPPYFGLLFPLLMLP
VVLLLPFGPYLRWGKAEAAPLKALGTRAGIAAIACALVGSVFADGQAKAIAGMGVAAWVAAGTALYVVKRWRDMPRGRRF
PAEMAGMLIAHAGVAVFVAGVLVSESLSVERDVRLSPGQSAQVAGYSFRFDGVQLVDGPNWKAEQGSVQVSRNGQVVAQL
HPQKRLYSSERIQTESAIDPGITRDLYVALGEPLDDEHIENDWTLRLYYKPFIRWIWAGGLLMMLGGFVSACARRFRAPV
TAHPLAASPAQPALVIAQESHP
>Mature_661_residues
TPELGQIALILALLLSLAQGVVPLIGAWRGNTALMGVARPAAVGQAVFVWMAFGLLAWSLLSLDFSVGYVAANANIALPW
YYRVAAVWGAHEGSLLLWIAILATWTVLLAAFSRHLPQHFAARVLAILGLISVGFLAFILLTSNPFGRLSPIPLDGNELN
PVLQDPGMTFHPPVLYTGYVGFSVAFAFAVAALLGGELEQAWVRWARPWTNVAWACLTAGIVAGSWWAYAELGWGGWWFW
DPVENASFMPWLVGTALIHSQAVTEKRGSLRAWTILLSILAFSLSLLGTFLVRSGVLTSVHAFAADPRRGLYILIFLVAV
VGGSLLLYALRAPKIASGKPFAAASRETGILIGNLLLTVAAAMVLLGTLFPLIADAFALGKVSVGPPYFGLLFPLLMLPV
VLLLPFGPYLRWGKAEAAPLKALGTRAGIAAIACALVGSVFADGQAKAIAGMGVAAWVAAGTALYVVKRWRDMPRGRRFP
AEMAGMLIAHAGVAVFVAGVLVSESLSVERDVRLSPGQSAQVAGYSFRFDGVQLVDGPNWKAEQGSVQVSRNGQVVAQLH
PQKRLYSSERIQTESAIDPGITRDLYVALGEPLDDEHIENDWTLRLYYKPFIRWIWAGGLLMMLGGFVSACARRFRAPVT
AHPLAASPAQPALVIAQESHP

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=657, Percent_Identity=50.3805175038052, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI1790511, Length=579, Percent_Identity=36.9602763385147, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 70982; Mature: 70851

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPELGQIALILALLLSLAQGVVPLIGAWRGNTALMGVARPAAVGQAVFVWMAFGLLAWS
CCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
LLSLDFSVGYVAANANIALPWYYRVAAVWGAHEGSLLLWIAILATWTVLLAAFSRHLPQH
HHHHHHEEEEEEECCCEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAARVLAILGLISVGFLAFILLTSNPFGRLSPIPLDGNELNPVLQDPGMTFHPPVLYTGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHEEHH
VGFSVAFAFAVAALLGGELEQAWVRWARPWTNVAWACLTAGIVAGSWWAYAELGWGGWWF
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEE
WDPVENASFMPWLVGTALIHSQAVTEKRGSLRAWTILLSILAFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFAADPRRGLYILIFLVAVVGGSLLLYALRAPKIASGKPFAAASRETGILIGNLLLTV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AAAMVLLGTLFPLIADAFALGKVSVGPPYFGLLFPLLMLPVVLLLPFGPYLRWGKAEAAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCH
LKALGTRAGIAAIACALVGSVFADGQAKAIAGMGVAAWVAAGTALYVVKRWRDMPRGRRF
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAEMAGMLIAHAGVAVFVAGVLVSESLSVERDVRLSPGQSAQVAGYSFRFDGVQLVDGPN
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCEEEEECCEEEECCCC
WKAEQGSVQVSRNGQVVAQLHPQKRLYSSERIQTESAIDPGITRDLYVALGEPLDDEHIE
CCCCCCCEEEECCCCEEEEECCHHHHHHHHHHCHHHCCCCCCCHHHHHHCCCCCCCCCCC
NDWTLRLYYKPFIRWIWAGGLLMMLGGFVSACARRFRAPVTAHPLAASPAQPALVIAQES
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECC
HP
CC
>Mature Secondary Structure 
TPELGQIALILALLLSLAQGVVPLIGAWRGNTALMGVARPAAVGQAVFVWMAFGLLAWS
CCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
LLSLDFSVGYVAANANIALPWYYRVAAVWGAHEGSLLLWIAILATWTVLLAAFSRHLPQH
HHHHHHEEEEEEECCCEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAARVLAILGLISVGFLAFILLTSNPFGRLSPIPLDGNELNPVLQDPGMTFHPPVLYTGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHEEHH
VGFSVAFAFAVAALLGGELEQAWVRWARPWTNVAWACLTAGIVAGSWWAYAELGWGGWWF
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEE
WDPVENASFMPWLVGTALIHSQAVTEKRGSLRAWTILLSILAFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFAADPRRGLYILIFLVAVVGGSLLLYALRAPKIASGKPFAAASRETGILIGNLLLTV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AAAMVLLGTLFPLIADAFALGKVSVGPPYFGLLFPLLMLPVVLLLPFGPYLRWGKAEAAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCH
LKALGTRAGIAAIACALVGSVFADGQAKAIAGMGVAAWVAAGTALYVVKRWRDMPRGRRF
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAEMAGMLIAHAGVAVFVAGVLVSESLSVERDVRLSPGQSAQVAGYSFRFDGVQLVDGPN
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCEEEEECCEEEECCCC
WKAEQGSVQVSRNGQVVAQLHPQKRLYSSERIQTESAIDPGITRDLYVALGEPLDDEHIE
CCCCCCCEEEECCCCEEEEECCHHHHHHHHHHCHHHCCCCCCCHHHHHHCCCCCCCCCCC
NDWTLRLYYKPFIRWIWAGGLLMMLGGFVSACARRFRAPVTAHPLAASPAQPALVIAQES
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECC
HP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]