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The map label for this gene is fadH [H]

Identifier: 78046595

GI number: 78046595

Start: 1165192

End: 1167231

Strand: Reverse

Name: fadH [H]

Synonym: XCV1039

Alternate gene names: 78046595

Gene position: 1167231-1165192 (Counterclockwise)

Preceding gene: 78046596

Following gene: 78046594

Centisome position: 22.54

GC content: 66.27

Gene sequence:

>2040_bases
ATGTCGCCCGCCACCGGCCCCTCCGCCTTGTCCTTCCCGCACCTGTTCACTCCGCTCGATCTGGGCTTCACGCAATTGCG
TAATCGGGTCCTGATGGGCTCGATGCACACGGGCCTGGAAGACCGTGCGCGCGACTTCCCCAGGTTGGCGGCGTATTTCG
CCGAGCGCGCCGCCGGTGGCGTGGGCCTGATCGTGACCGGTGGGTTTTCGCCCAATGTGGTGGGCTGGCTCAAGCCATTC
GGCGGCAAGTTATCGTGGCCGTGGGAAGTACGCCCGCATCGCCAGGTCACCCGCGCAGTCCACGAACACGGCGCCAAGAT
CTGCCTGCAGCTGCTGCACGCTGGGCGCTGTGCGTACCACCCGCTGTCGGTTGCGCCGTCCAGGCTCAAGGCACCGATCA
ACCCGTTCACTCCGCGTGCGTTGTCGGCCGGCGCGGTCGACCGGCAGATCGCCGCGTATGCGCGTGCCGCGCGGCTGGCG
CGCGAGGCAGGCTACGACGGCGTCGAGGTCATGGGCTCGGAAGGCTATCTGATCAATGAATTCACCGCCGCGCGCACCAA
TCGGCGCAGCGACGCGTGGGGCGGCGATGCCAGCAAGCGCATGCGCTTTGCGGTGGAGATCGTGCGACGCATCCGCGAGG
CCTGCGGGCCGGACTTCATCATCATCTATCGGCTGTCGCTGGTGGATCTGGTCGAAGACGGCAACCAATGGCAGGAAATC
CTGGCGCAGGCACAGGCGATCGAAGCGGCCGGCGCGACCATCATCAATTCCGGTATCGGCTGGCACGAAGCGCGCATTCC
CACCATCGCCACCTCGGTGCCGCGCGCCGCGTTTGTCGGGGTCACCGCCAAGCTCAAACCGCATCTGCGCATTCCGGTGG
TGGCCACCAACCGCATCAACATGCCGGAGGTGGCCGAGCGCATCCTGGCCGACGGTGCCGCAGATATGGTGTCGCTGGCG
CGGCCGCTGCTGGCCGACCCGCAGTGGACCAATAAAGCGCGCGCCGGGCAGTCGCACACCATCAATACGTGTATCGCCTG
TAATCAGGCCTGCCTGGATCATGTTTTCGACAACAAGCTGGCCAGCTGCCTGGTCAACCCACGTGCCGCACACGAGACCG
AACTCAACTACACCCCGACTGCCACGCCCAAGCGCATCGCCGTGGTCGGGGCCGGCCCGGCCGGTCTGGCCTGCGCGACA
GTGGCGGCAGAACGCGGGCACCGGGTGACCTTGTTCGAGGCTAGCGATGCGATCGGGGGGCAATTCAATGTCGCCAGGCG
CATTCCGGGCAAGGAAGAATTCAACGAGACGTTGCGTTACTTCGGCCATCGCATCGAAGCGACCGGCGTGCAGCTGCGTC
TGAACACCCCGGTACAGGCGGCCGATCTGAAAGACTTTGACGAAGTCGTGCTGGCAACCGGCATCGAGCCGCGCAAGGTG
GATTTCCCCGGTGCCGATCATCCGATGGTGGTGAGCTACCTCGACGTGGTGCTGGGCCGCCACGTGGCCGCCGACAAGGT
GGCGATCATCGGTGCCGGCGGCATTGGCTTTGATGTCGGTGAGTTTCTGGTGCACACCGGCCAATCGCCTGCGCTGGATC
CGCAGCGCTGGATGGCCGAATGGGGCGTAGACCCGAACTTCGAAGCGCGCGGTGCGTTGACCAAACCGCAACCCGAGCGC
GCCGCCCGCCAGGTCTGGTTGTTGCAGCGCAGCTCCGGTAAGCCTGGTGCACGCCTGGGCAAGACCACCGGCTGGATCCA
CCGCGCGACGCTCAAGGCCAAGGGCGTCAAGATGCTCGGCGGCGTGGAATATCTGGGCGTGGACGATGCCGGCCTGCGCA
TTCGCGTGGAAGGCAGCGAACAGCTGCTGGATGTCGGTACGGTGGTGGTGTGCGCCGGGCAGGAGCCGCGTCGCGAGTTG
CTGGCTGCGCTGCAGGCCAATGGCCAGCAGCCGCATTTGATCGGTGGCGCGGACGTGGCGGCCGAACTGGATGCCAAGCG
CGCGATCAACCAGGCAAGTCGGCTGGCCGCGACCCTGTAA

Upstream 100 bases:

>100_bases
GGGCGTCTGCAGCATCGGCGCGCCGCTGCATGCACCAGGACTTGCCGCCAGACCGGTTTGCCGGCATCGTGCGCAATCCG
TACGCAAGCGTATCCACATC

Downstream 100 bases:

>100_bases
CGGGTTTTCGAAGACGGCGTCACCACGACGCCGTCGTTGTGTTCGCGTCCTGGCTGCACCGCTGACGTGCATGCGGCGCG
ACCGACGCCGACATGCACGC

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MSPATGPSALSFPHLFTPLDLGFTQLRNRVLMGSMHTGLEDRARDFPRLAAYFAERAAGGVGLIVTGGFSPNVVGWLKPF
GGKLSWPWEVRPHRQVTRAVHEHGAKICLQLLHAGRCAYHPLSVAPSRLKAPINPFTPRALSAGAVDRQIAAYARAARLA
REAGYDGVEVMGSEGYLINEFTAARTNRRSDAWGGDASKRMRFAVEIVRRIREACGPDFIIIYRLSLVDLVEDGNQWQEI
LAQAQAIEAAGATIINSGIGWHEARIPTIATSVPRAAFVGVTAKLKPHLRIPVVATNRINMPEVAERILADGAADMVSLA
RPLLADPQWTNKARAGQSHTINTCIACNQACLDHVFDNKLASCLVNPRAAHETELNYTPTATPKRIAVVGAGPAGLACAT
VAAERGHRVTLFEASDAIGGQFNVARRIPGKEEFNETLRYFGHRIEATGVQLRLNTPVQAADLKDFDEVVLATGIEPRKV
DFPGADHPMVVSYLDVVLGRHVAADKVAIIGAGGIGFDVGEFLVHTGQSPALDPQRWMAEWGVDPNFEARGALTKPQPER
AARQVWLLQRSSGKPGARLGKTTGWIHRATLKAKGVKMLGGVEYLGVDDAGLRIRVEGSEQLLDVGTVVVCAGQEPRREL
LAALQANGQQPHLIGGADVAAELDAKRAINQASRLAATL

Sequences:

>Translated_679_residues
MSPATGPSALSFPHLFTPLDLGFTQLRNRVLMGSMHTGLEDRARDFPRLAAYFAERAAGGVGLIVTGGFSPNVVGWLKPF
GGKLSWPWEVRPHRQVTRAVHEHGAKICLQLLHAGRCAYHPLSVAPSRLKAPINPFTPRALSAGAVDRQIAAYARAARLA
REAGYDGVEVMGSEGYLINEFTAARTNRRSDAWGGDASKRMRFAVEIVRRIREACGPDFIIIYRLSLVDLVEDGNQWQEI
LAQAQAIEAAGATIINSGIGWHEARIPTIATSVPRAAFVGVTAKLKPHLRIPVVATNRINMPEVAERILADGAADMVSLA
RPLLADPQWTNKARAGQSHTINTCIACNQACLDHVFDNKLASCLVNPRAAHETELNYTPTATPKRIAVVGAGPAGLACAT
VAAERGHRVTLFEASDAIGGQFNVARRIPGKEEFNETLRYFGHRIEATGVQLRLNTPVQAADLKDFDEVVLATGIEPRKV
DFPGADHPMVVSYLDVVLGRHVAADKVAIIGAGGIGFDVGEFLVHTGQSPALDPQRWMAEWGVDPNFEARGALTKPQPER
AARQVWLLQRSSGKPGARLGKTTGWIHRATLKAKGVKMLGGVEYLGVDDAGLRIRVEGSEQLLDVGTVVVCAGQEPRREL
LAALQANGQQPHLIGGADVAAELDAKRAINQASRLAATL
>Mature_678_residues
SPATGPSALSFPHLFTPLDLGFTQLRNRVLMGSMHTGLEDRARDFPRLAAYFAERAAGGVGLIVTGGFSPNVVGWLKPFG
GKLSWPWEVRPHRQVTRAVHEHGAKICLQLLHAGRCAYHPLSVAPSRLKAPINPFTPRALSAGAVDRQIAAYARAARLAR
EAGYDGVEVMGSEGYLINEFTAARTNRRSDAWGGDASKRMRFAVEIVRRIREACGPDFIIIYRLSLVDLVEDGNQWQEIL
AQAQAIEAAGATIINSGIGWHEARIPTIATSVPRAAFVGVTAKLKPHLRIPVVATNRINMPEVAERILADGAADMVSLAR
PLLADPQWTNKARAGQSHTINTCIACNQACLDHVFDNKLASCLVNPRAAHETELNYTPTATPKRIAVVGAGPAGLACATV
AAERGHRVTLFEASDAIGGQFNVARRIPGKEEFNETLRYFGHRIEATGVQLRLNTPVQAADLKDFDEVVLATGIEPRKVD
FPGADHPMVVSYLDVVLGRHVAADKVAIIGAGGIGFDVGEFLVHTGQSPALDPQRWMAEWGVDPNFEARGALTKPQPERA
ARQVWLLQRSSGKPGARLGKTTGWIHRATLKAKGVKMLGGVEYLGVDDAGLRIRVEGSEQLLDVGTVVVCAGQEPRRELL
AALQANGQQPHLIGGADVAAELDAKRAINQASRLAATL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=669, Percent_Identity=58.4454409566517, Blast_Score=771, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=342, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=297, Percent_Identity=25.5892255892256, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17559802, Length=269, Percent_Identity=27.5092936802974, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=257, Percent_Identity=26.4591439688716, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=256, Percent_Identity=25, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540738, Length=300, Percent_Identity=24.3333333333333, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72001454, Length=260, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17566914, Length=300, Percent_Identity=26, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=239, Percent_Identity=25.9414225941423, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73088; Mature: 72956

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPATGPSALSFPHLFTPLDLGFTQLRNRVLMGSMHTGLEDRARDFPRLAAYFAERAAGG
CCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
VGLIVTGGFSPNVVGWLKPFGGKLSWPWEVRPHRQVTRAVHEHGAKICLQLLHAGRCAYH
EEEEEECCCCCCCEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PLSVAPSRLKAPINPFTPRALSAGAVDRQIAAYARAARLAREAGYDGVEVMGSEGYLINE
CCCCCHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEC
FTAARTNRRSDAWGGDASKRMRFAVEIVRRIREACGPDFIIIYRLSLVDLVEDGNQWQEI
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHH
LAQAQAIEAAGATIINSGIGWHEARIPTIATSVPRAAFVGVTAKLKPHLRIPVVATNRIN
HHHHHHHHHCCCCEEECCCCCCCCCCCHHHHCCCCHHHEEEEEECCCCEEEEEEECCCCC
MPEVAERILADGAADMVSLARPLLADPQWTNKARAGQSHTINTCIACNQACLDHVFDNKL
CHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ASCLVNPRAAHETELNYTPTATPKRIAVVGAGPAGLACATVAAERGHRVTLFEASDAIGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCC
QFNVARRIPGKEEFNETLRYFGHRIEATGVQLRLNTPVQAADLKDFDEVVLATGIEPRKV
CEEEHHCCCCHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCCCHHHHHHHHCCCCCCEE
DFPGADHPMVVSYLDVVLGRHVAADKVAIIGAGGIGFDVGEFLVHTGQSPALDPQRWMAE
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHH
WGVDPNFEARGALTKPQPERAARQVWLLQRSSGKPGARLGKTTGWIHRATLKAKGVKMLG
CCCCCCCCCCCCCCCCCHHHHHHHEEHEECCCCCCCCCCCCCCCCEEEEEHHHCCCHHHC
GVEYLGVDDAGLRIRVEGSEQLLDVGTVVVCAGQEPRRELLAALQANGQQPHLIGGADVA
CEEEECCCCCCCEEEECCCHHHEECCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCHH
AELDAKRAINQASRLAATL
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPATGPSALSFPHLFTPLDLGFTQLRNRVLMGSMHTGLEDRARDFPRLAAYFAERAAGG
CCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
VGLIVTGGFSPNVVGWLKPFGGKLSWPWEVRPHRQVTRAVHEHGAKICLQLLHAGRCAYH
EEEEEECCCCCCCEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PLSVAPSRLKAPINPFTPRALSAGAVDRQIAAYARAARLAREAGYDGVEVMGSEGYLINE
CCCCCHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEC
FTAARTNRRSDAWGGDASKRMRFAVEIVRRIREACGPDFIIIYRLSLVDLVEDGNQWQEI
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHH
LAQAQAIEAAGATIINSGIGWHEARIPTIATSVPRAAFVGVTAKLKPHLRIPVVATNRIN
HHHHHHHHHCCCCEEECCCCCCCCCCCHHHHCCCCHHHEEEEEECCCCEEEEEEECCCCC
MPEVAERILADGAADMVSLARPLLADPQWTNKARAGQSHTINTCIACNQACLDHVFDNKL
CHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ASCLVNPRAAHETELNYTPTATPKRIAVVGAGPAGLACATVAAERGHRVTLFEASDAIGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCC
QFNVARRIPGKEEFNETLRYFGHRIEATGVQLRLNTPVQAADLKDFDEVVLATGIEPRKV
CEEEHHCCCCHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCCCHHHHHHHHCCCCCCEE
DFPGADHPMVVSYLDVVLGRHVAADKVAIIGAGGIGFDVGEFLVHTGQSPALDPQRWMAE
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHH
WGVDPNFEARGALTKPQPERAARQVWLLQRSSGKPGARLGKTTGWIHRATLKAKGVKMLG
CCCCCCCCCCCCCCCCCHHHHHHHEEHEECCCCCCCCCCCCCCCCEEEEEHHHCCCHHHC
GVEYLGVDDAGLRIRVEGSEQLLDVGTVVVCAGQEPRRELLAALQANGQQPHLIGGADVA
CEEEECCCCCCCEEEECCCHHHEECCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCHH
AELDAKRAINQASRLAATL
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]