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The map label for this gene is nudF [C]

Identifier: 78046503

GI number: 78046503

Start: 1075357

End: 1075908

Strand: Reverse

Name: nudF [C]

Synonym: XCV0947

Alternate gene names: 78046503

Gene position: 1075908-1075357 (Counterclockwise)

Preceding gene: 78046504

Following gene: 78046502

Centisome position: 20.78

GC content: 65.04

Gene sequence:

>552_bases
ATGAACCGACACGACACCCCGCCCACCGTGGTCTACGAAGGCAAGTACCAGCGCATGGTCGTGCGTGGCACCTGGGAGTA
TTCCGAGCGTGTGCATGCCGGCGGCCTGGCCGCGATCATCGTGGCGGTGACGCCGGACGATGCGATGTTGTTCGTCGAAC
AGTTCCGCGTGCCGCTGCAGGCACGCACCATCGAAATGCCGGCCGGACTGGTAGGCGATGTGCATGCCGATGAGTCGATC
GAACTGTCGGCCATTCGCGAACTGGAAGAAGAAACCGGCTGGACCGCCGAGCATGCCGAAGTGTTGATGATCGGCCCCAC
CTCGGCCGGTGCCAGCAGCGAGAAGATCGCCTTCGTGCGCGCCACCGGTCTGCGCAAGGTCGGCGACGGCGGCGGCGATG
CCAGCGAAGACATCACCGTGCACGCAATTCCACGCGAGCAGGTCGGTGCCTGGCTGGTGCAGAAGATGGCCGAGGGCTAT
CAGATGGACCCCAAGCTGTGGGCCGGCCTGTATCTGGCCGATCACGCATTGGACGGCACCCCGCGTGGCTGA

Upstream 100 bases:

>100_bases
GCCTGCGCTTCGGCCCGCTCACCCGGCGCCGTCTGTTGGCCGCCAGCACCGGCGCCGCCGCACCGTTTCCTCCCGTTTCC
CTGGCACAAGGTCCCCGCCC

Downstream 100 bases:

>100_bases
CGCAGCCATCGAACCCTTGCTCGGCGCCGACGATCCGGCGCCGTTCACCGTGCACAACGCGCAGGCCGCATCGCCGTGGC
TGTTGATCGCCGACCACGCC

Product: NUDIX hydrolase family protein

Products: AMP; D-Ribose 5- Phosphate. [C]

Alternate protein names: ADP-Ribose Pyrophosphatase; NTP Pyrophosphohydrolase; MutT-Like Protein; Nudix Hydrolase Family Protein; MutT/Nudix Family Protein

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNRHDTPPTVVYEGKYQRMVVRGTWEYSERVHAGGLAAIIVAVTPDDAMLFVEQFRVPLQARTIEMPAGLVGDVHADESI
ELSAIRELEEETGWTAEHAEVLMIGPTSAGASSEKIAFVRATGLRKVGDGGGDASEDITVHAIPREQVGAWLVQKMAEGY
QMDPKLWAGLYLADHALDGTPRG

Sequences:

>Translated_183_residues
MNRHDTPPTVVYEGKYQRMVVRGTWEYSERVHAGGLAAIIVAVTPDDAMLFVEQFRVPLQARTIEMPAGLVGDVHADESI
ELSAIRELEEETGWTAEHAEVLMIGPTSAGASSEKIAFVRATGLRKVGDGGGDASEDITVHAIPREQVGAWLVQKMAEGY
QMDPKLWAGLYLADHALDGTPRG
>Mature_183_residues
MNRHDTPPTVVYEGKYQRMVVRGTWEYSERVHAGGLAAIIVAVTPDDAMLFVEQFRVPLQARTIEMPAGLVGDVHADESI
ELSAIRELEEETGWTAEHAEVLMIGPTSAGASSEKIAFVRATGLRKVGDGGGDASEDITVHAIPREQVGAWLVQKMAEGY
QMDPKLWAGLYLADHALDGTPRG

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.13 [C]

Molecular weight: Translated: 19883; Mature: 19883

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRHDTPPTVVYEGKYQRMVVRGTWEYSERVHAGGLAAIIVAVTPDDAMLFVEQFRVPLQ
CCCCCCCCEEEECCCEEEEEEEECCHHHHHCCCCCEEEEEEEECCCCCEEEHHHHCCCCE
ARTIEMPAGLVGDVHADESIELSAIRELEEETGWTAEHAEVLMIGPTSAGASSEKIAFVR
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEE
ATGLRKVGDGGGDASEDITVHAIPREQVGAWLVQKMAEGYQMDPKLWAGLYLADHALDGT
ECCCEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHEEEECCCCCCC
PRG
CCC
>Mature Secondary Structure
MNRHDTPPTVVYEGKYQRMVVRGTWEYSERVHAGGLAAIIVAVTPDDAMLFVEQFRVPLQ
CCCCCCCCEEEECCCEEEEEEEECCHHHHHCCCCCEEEEEEEECCCCCEEEHHHHCCCCE
ARTIEMPAGLVGDVHADESIELSAIRELEEETGWTAEHAEVLMIGPTSAGASSEKIAFVR
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEE
ATGLRKVGDGGGDASEDITVHAIPREQVGAWLVQKMAEGYQMDPKLWAGLYLADHALDGT
ECCCEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHEEEECCCCCCC
PRG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP-Ribose; H2O [C]

Specific reaction: ADP-Ribose + H2O = AMP + D-Ribose 5- Phosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA