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The map label for this gene is rbsK [H]

Identifier: 78046426

GI number: 78046426

Start: 1000821

End: 1001771

Strand: Reverse

Name: rbsK [H]

Synonym: XCV0870

Alternate gene names: 78046426

Gene position: 1001771-1000821 (Counterclockwise)

Preceding gene: 78046427

Following gene: 78046425

Centisome position: 19.34

GC content: 68.03

Gene sequence:

>951_bases
ATGAGTTCGGTCGTCGTTGTCGGGTCCTTCAATGTCGATCACGTGTGGCGCTGCGATGCCTTGCCGGTGCCGGGCGCGAC
CATCGCCGGGCGCTACAGCACCGGCCCGGGCGGCAAGGGCTTCAATCAGGCGGTTGCGGCCGCACGCGCTGGCGCCAAGA
CGCATTTCTTGTGCGCGCTGGGCGACGACGCCGGTGGTGCGCTGGCACGCTCGCTGGCCGCGCAGGACGGCTTTTCGCTG
ATCGCCGAGCCCAGCAATGAACCGACCGGCACCGGCGGCATCTATGTCGACGGGCACGGCCGCAACACCATCGTGATCGG
CGCCGGCGCCAACGCCGTGTTGAGCCCCGCCTTCATCGAGAACCAACGCCCGCTGGTGGCTGCGGCAAAGGTGTTGCTGG
CGCAGCTGGAATCCCCGGCCGAGACGATCGAGTCCGCACTGGCGCTGGCGCACGAATGTGGCGTGCTGACCGTGCTCAAT
GCCGCACCGGCCAATGCACCGACCTCGATTGGCCTGCTCAAGCTCTCGGATGTACTGACGCCCAACGAAACCGAATTCGC
CGCACTGCTCGGTCGCCATGTCGGCGAGCGCATCAATGCCGACGACGTCGCCGCGCTGGACGGCAATACGTTGCATTCGT
TGTGCCGCAAGCTGCTGCCGGGCGGTACCGTAGTGGTGACCCTGGGCGCGGTGGGCGCCTTCATTTCGCACGCCGAAGAA
CAGCTGCGCGGCGATAGCCAGGCGCATTACCGCGTGGGCGCGGAAAGCGCGCAGACCATCGACACCACCGGCGCGGGCGA
TGCCTTCAACGGTGCGCTGGTTGCCTCGCTGGCGCAGGTGCCGGCTGCGAGCTTCGCAACCCACGTGCGCTTTGCCACCC
GTTATGCGGCGCGCTCCACCGAGGTGGAAGGTGCGGCGGTGTCGATGCCGCGGCTGCGCGCGGACGACTGA

Upstream 100 bases:

>100_bases
TTTCGGTTGAGGCGGTGCGGGTTCATCGGCGTGACGGTCTAATCACTGCGCGCCGCGTTTCATCCAGTCTTTCAAGTCAG
TCATTCAAGGCAAGGTATTT

Downstream 100 bases:

>100_bases
GACCACGGTTCACTGCCATTGGCGTGCGCCACGCGCGCATGCCCTCGACACCGCACCCACGCAGGCGCCCAGGTTTTTTC
CAGGAATGCGCGTGCATGTC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGAKTHFLCALGDDAGGALARSLAAQDGFSL
IAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIENQRPLVAAAKVLLAQLESPAETIESALALAHECGVLTVLN
AAPANAPTSIGLLKLSDVLTPNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
QLRGDSQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQVPAASFATHVRFATRYAARSTEVEGAAVSMPRLRADD

Sequences:

>Translated_316_residues
MSSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGAKTHFLCALGDDAGGALARSLAAQDGFSL
IAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIENQRPLVAAAKVLLAQLESPAETIESALALAHECGVLTVLN
AAPANAPTSIGLLKLSDVLTPNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
QLRGDSQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQVPAASFATHVRFATRYAARSTEVEGAAVSMPRLRADD
>Mature_315_residues
SSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGAKTHFLCALGDDAGGALARSLAAQDGFSLI
AEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIENQRPLVAAAKVLLAQLESPAETIESALALAHECGVLTVLNA
APANAPTSIGLLKLSDVLTPNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEEQ
LRGDSQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQVPAASFATHVRFATRYAARSTEVEGAAVSMPRLRADD

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=311, Percent_Identity=35.3697749196142, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1790193, Length=281, Percent_Identity=41.6370106761566, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17532905, Length=316, Percent_Identity=31.0126582278481, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=27.4626865671642, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI20128807, Length=318, Percent_Identity=35.5345911949685, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24583886, Length=311, Percent_Identity=30.2250803858521, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32078; Mature: 31947

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00584 PFKB_KINASES_2 ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGAKTHFLCAL
CCCEEEEECCCCCCEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
GDDAGGALARSLAAQDGFSLIAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIE
CCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHC
NQRPLVAAAKVLLAQLESPAETIESALALAHECGVLTVLNAAPANAPTSIGLLKLSDVLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEHHCCC
PNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
CCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHH
QLRGDSQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQVPAASFATHVRFATRYAARST
HHCCCCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
EVEGAAVSMPRLRADD
CCCCCEECCCCCCCCC
>Mature Secondary Structure 
SSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGAKTHFLCAL
CCEEEEECCCCCCEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
GDDAGGALARSLAAQDGFSLIAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIE
CCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHC
NQRPLVAAAKVLLAQLESPAETIESALALAHECGVLTVLNAAPANAPTSIGLLKLSDVLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEHHCCC
PNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
CCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHH
QLRGDSQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQVPAASFATHVRFATRYAARST
HHCCCCCCEEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
EVEGAAVSMPRLRADD
CCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]